Zobrazeno 1 - 10
of 809
pro vyhledávání: '"H von Boehmer"'
Autor:
M. Nabholz, M Cianfriglia, H Pohlit, Oreste Acuto, Andreas Conzelmann, Werner Haas, H von Boehmer, H R McDonald, Judy Johnson
Following the demonstration that hybrids between normal B-lymphocytes and myeloma cell lines continue to secrete antibodies with the same specificity as those produced by the parental B-cells1, many groups have tried to use this approach to obtain ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a886f40df4d0795ec2fa86a869ce2d20
https://ora.ox.ac.uk/objects/uuid:84d2ea3d-55cc-48c3-9712-a63f401c7fd3
https://ora.ox.ac.uk/objects/uuid:84d2ea3d-55cc-48c3-9712-a63f401c7fd3
Autor:
H. von Boehmer
Publikováno v:
Scandinavian Journal of Immunology. 62:49-54
Recent years have witnessed the revival of suppressor T cells that control immunity by interfering with the generation of effector T-cell function in vivo. The discovery that CD4 T cells with the CD25 surface marker were enriched in suppressor activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8917445676e069eb918d169fcbfa38f5
https://doi.org/10.1111/j.1365-3083.2005.01609.x
https://doi.org/10.1111/j.1365-3083.2005.01609.x
Publikováno v:
The Journal of Experimental Medicine
The Journal of experimental medicine, vol 182, iss 5
The Journal of experimental medicine, vol 182, iss 5
The pre-T cell receptor (TCR) complex regulates early T cell development and consists of a heterodimer of the TCR-beta subunit in association with the pre-TCR-alpha chain. Notably, in contrast to alpha/beta-expressing T cells, several studies suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d21cdb655a1d9a15e61da20d2ba48d
http://europepmc.org/articles/PMC2192214
http://europepmc.org/articles/PMC2192214
Autor:
Ralf Kühn, Urs Müller, Wojciech Swat, H von Boehmer, Catherine Laplace, Fehling Hj, Klaus Rajewsky
Publikováno v:
Science. 265:1234-1237
Proteasomes degrade endogenous proteins. Two subunits, LMP-2 and LMP-7, are encoded in a region of the major histocompatibility complex (MHC) that is critical for class I-restricted antigen presentation. Mice with a targeted deletion of the gene enco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca9873aae2779759fa5d0e958e1dc8d
https://doi.org/10.1126/science.8066463
https://doi.org/10.1126/science.8066463
Publikováno v:
The Journal of Experimental Medicine
We describe mice that express a transgenic T cell receptor alpha/beta (TCR-alpha/beta) specific for peptide 111-119 from influenza hemagglutinin presented by I-Ed class II major histocompatibility complex (MHC) molecules. The transgenic TCR is expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48276561e1bca458a1d7d0b1770c7838
https://doi.org/10.1084/jem.180.1.25
https://doi.org/10.1084/jem.180.1.25
Publikováno v:
Proceedings of the National Academy of Sciences. 91:1376-1380
To explore the role of bcl-2 in T-cell development, a bcl-2 transgene was introduced into mice expressing a T-cell receptor (TCR) transgene encoding reactivity for the mouse male antigen HY presented by the H-2Db class I antigen of the major histocom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c055ea81135caf78b0fc05743b3071f
https://doi.org/10.1073/pnas.91.4.1376
https://doi.org/10.1073/pnas.91.4.1376
Autor:
H von Boehmer, Katrin Hafen
Publikováno v:
The Journal of Experimental Medicine
We have determined the life span of naive CD4-8+ T cells in T cell receptor transgenic mice. We find that such cells do not divide in secondary lymphoid organs in both normal euthymic mice and T cell-deficient mice. By both continuous labeling and by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052b61d037177553f8669d71ec44612c
https://doi.org/10.1084/jem.177.4.891
https://doi.org/10.1084/jem.177.4.891
Publikováno v:
The EMBO Journal. 11:2735-2745
Transfected T cell receptor (TCR) beta chain genes are expressed as homodimers on the surface of immature (Sci/ET27F) but not on mature (58 alpha-beta-) T cell lines which lack TCR alpha, gamma and delta chains. The homodimer on Sci/ET27F cells is ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6775531cd9d592d8ab019604c61b5900
https://doi.org/10.1002/j.1460-2075.1992.tb05339.x
https://doi.org/10.1002/j.1460-2075.1992.tb05339.x
Publikováno v:
Proceedings of the National Academy of Sciences. 89:5336-5340
We have studied T-cell receptor (TCR) and alpha/alpha CD8 expression in thymus-independent intraepithelial lymphocytes (TI IELs) from the gut of mice bearing transgenic (TG) TCR alpha beta specific for the male antigen, presented by H-2Db class I maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01758cd9615673fddd5b13852118575
https://doi.org/10.1073/pnas.89.12.5336
https://doi.org/10.1073/pnas.89.12.5336
Publikováno v:
The Journal of Experimental Medicine
In male mice that express a transgenic alpha/beta T cell receptor (TCR) specific for a male-specific peptide presented by class I Db major histocompatibility complex (MHC) molecules, we describe an unusual lineage of alpha/beta T cells that are thymu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18aacfda693bcb560f428c8875925c99
https://doi.org/10.1084/jem.174.5.1001
https://doi.org/10.1084/jem.174.5.1001