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Autor:
G. Goddard, B. Rozman, R. Cervera, H. Zinger, Yackov Berkun, Michael B. Blank, Ori Barzilai, Maya Ram, Y Shoenfeld, Nancy Agmon-Levin, Yaniv Sherer, Angela Tincani
Publikováno v:
Lupus. 18:1149-1153
Antiphospholipid syndrome is characterized by thrombosis and pregnancy loss. Infections are generally associated with autoimmune diseases, but in the setting of antiphospholipid syndrome this link has been suggested as having a pathogenic role. In th
Autor:
Rami Ben-Yosef, Dina Kazanov, D. Yona, Shahar Lev-Ari, Alex Starr, A. Figer, H. Zinger, Nadir Arber
Publikováno v:
Biomedicine & Pharmacotherapy. 59:S276-S280
Background and aim. - Adenocarcinoma of the Pancreas is a leading cause of cancer-related mortality, accounting for an estimated 30,000 deaths per year in the United States. Multiple studies have indicated that specific cyclooxygenase-2 (COX-2) inhib
Publikováno v:
The Journal of Immunology. 153:873-880
Experimental SLE can be induced in mice by immunization with a human mAb to DNA (16/6Id). Immunized mice develop Abs to the 16/6Id immunogen, DNA, and nuclear Ags. Subsequently, clinical manifestations of disease develop, including leukopenia, protei
Publikováno v:
Journal of clinical immunology. 20(4)
Two peptides based on the complementarity-determining regions (CDR) of a pathogenic murine anti-DNA antibody were employed in an attempt to prevent the spontaneous systemic lupus erythematosus (SLE)-like disease of (NZBxNZW)F1 mice. Female mice, at t
Publikováno v:
European journal of immunology. 29(7)
Mice deficient in beta2-microglobulin expression are resistant to the induction of experimental systemic lupus erythematosus (SLE). The present studies were designed to identify the beta2-microglobulin-dependent cell surface molecule(s) that confers
Publikováno v:
Journal of clinical immunology. 18(2)
(NZB x NZW)F1 mice spontaneously develop with age an autoimmune disease that resembles the human disease, systemic lupus erythematosus (SLE). The present study demonstrates that methimazole (MMI), an agent used in the treatment of autoimmune thyroid
Autor:
Fortune Kohen, M. Dayan, Zev Sthoeger, G. Mor, F. Kalush, Y. Amir Zaltman, Edna Mozes, H. Zinger
Publikováno v:
Annals of the New York Academy of Sciences. 815
Publikováno v:
Israel journal of medical sciences. 32(1)
Publikováno v:
The Journal of rheumatology. 21(12)
To determine the effects of the estrogen antagonist, tamoxifen, on the development and the course of experimental murine systemic lupus erythematosus (SLE).SLE was induced in naive BALB/c female mice by injection of the human monoclonal anti-DNA anti