Zobrazeno 1 - 3
of 3
pro vyhledávání: '"H W, Heetla"'
Publikováno v:
British journal of clinical pharmacology. 81(1)
Intrathecal baclofen (ITB) has proven to be an effective and safe treatment for severe spasticity. However, although ITB is used extensively, clinical decisions are based on very scarce pharmacokinetic-pharmacodynamic (PKPD) data. The aim of this stu
Publikováno v:
Spinal Cord, 48(6), 483-486. Nature Publishing Group
Study design: Pilot study.Objective: To study the effect of pulsatile bolus infusion of intrathecal baclofen (ITB) on daily ITB dose, in patients showing dose increases, probably due to tolerance.Setting: Department of neurology and neurosurgery, Uni
Publikováno v:
Spinal Cord, 47(10), 751-756. Nature Publishing Group
Study design: Retrospective study.Objectives: To study the incidence and management of tolerance in patients treated with intrathecal baclofen (ITB) therapy.Setting: Department of neurology and neurosurgery, University Medical Center Groningen, The N