Zobrazeno 1 - 10
of 24
pro vyhledávání: '"H V Raff"'
Publikováno v:
Infection and Immunity. 62:1776-1786
We determined the heavy (H)- and light (L)-chain variable (V) region nucleotide and translated amino acid sequences of the human immunoglobulin M(kappa) monoclonal antibody (MAb) 5E1, which is specific for the polysaccharide capsule of Escherichia co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8d83d2c2cefee3f2bc8e4315f86e56
https://doi.org/10.1128/iai.62.5.1776-1786.1994
https://doi.org/10.1128/iai.62.5.1776-1786.1994
Publikováno v:
The Journal of Immunology. 148:2469-2474
Human IgG1 mAb dimers specific for either group B streptococci or Escherichia coli K1 bacteria were formed using chemical cross-linkers. The effect of antibody valency on biologic efficacy was investigated by comparing the IgG dimers against the corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6fb02cb4ef93444d4cd868bf6377aea
https://doi.org/10.4049/jimmunol.148.8.2469
https://doi.org/10.4049/jimmunol.148.8.2469
Publikováno v:
The Journal of Immunology. 148:1879-1884
We have compared the opsonic and complement-triggering activity of transfectoma-derived, class-switched human IgG1 and IgM mAb (HumAb) against types Ia, II and III group B streptococci (GBS). These antibodies appear to be directed against the common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28ff8d5a87104dc19068cde39e12111e
https://doi.org/10.4049/jimmunol.148.6.1879
https://doi.org/10.4049/jimmunol.148.6.1879
Autor:
W R, Gombotz, S C, Pankey, D, Phan, R, Drager, K, Donaldson, K P, Antonsen, A S, Hoffman, H V, Raff
Publikováno v:
Pharmaceutical research. 11(5)
An IgM anti-group B Streptococcus monoclonal antibody (4B9) was found to undergo irreversible heat-induced aggregation at 50 degrees C. A variety of excipients was tested for their ability to inhibit antibody aggregation. The amount of 4B9 aggregatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81e310a95c8765d019d235d8d46478f1
https://pubmed.ncbi.nlm.nih.gov/8058628
https://pubmed.ncbi.nlm.nih.gov/8058628
Publikováno v:
Cancer research. 53(11)
The potential for enhancing antibody potency by increasing avidity was investigated using monoclonal IgG homodimers. Chemically linked dimers were made from a human-murine chimeric monoclonal IgG (ChiBR96) which strongly binds to a variety of breast,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c514894a06a901fd58c9b8f7e02461ae
https://pubmed.ncbi.nlm.nih.gov/8495420
https://pubmed.ncbi.nlm.nih.gov/8495420
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 148(8)
Human IgG1 mAb dimers specific for either group B streptococci or Escherichia coli K1 bacteria were formed using chemical cross-linkers. The effect of antibody valency on biologic efficacy was investigated by comparing the IgG dimers against the corr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::deb5fc0cc442a5d29dc8246e73ec4572
https://pubmed.ncbi.nlm.nih.gov/1560202
https://pubmed.ncbi.nlm.nih.gov/1560202
Publikováno v:
Clinical reviews in allergy. 10(1-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cdff02a3e709358787232ba330bfcd56
https://pubmed.ncbi.nlm.nih.gov/1606522
https://pubmed.ncbi.nlm.nih.gov/1606522
Autor:
M D Sadick, H V Raff
Publikováno v:
Infection and Immunity. 47:395-400
The accessibility of particular Leishmania tropica promastigote (extracellular) and amastigote (intracellular) membrane molecules might be related to the relative abilities of the two stages to induce host immune responses. To examine the exposure of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913f8804ecc201e828cbc62f2b4ffc6b
https://doi.org/10.1128/iai.47.2.395-400.1985
https://doi.org/10.1128/iai.47.2.395-400.1985
Publikováno v:
The Journal of Experimental Medicine
Group B streptococcal (GBS) infections cause significant mortality and morbidity among infants. Passive antibody immunotherapy has been proposed as treatment for infected infants. To this end, two human mAb-secreting cell lines were produced by EBV i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39072bac449c02ebde2c39f8a0c720d4
https://doi.org/10.1084/jem.168.3.905
https://doi.org/10.1084/jem.168.3.905
Publikováno v:
The Journal of Experimental Medicine
Utilizing somatic cell hybridization, we have developed a monoclonal antibody that interacts only with cells of the monocyte/macrophage (M phi) line and not with other myeloid or lymphoid cells. This antibody detects a 120,000-dalton determinant pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61846340832557acde6e025d9d193f1b
http://europepmc.org/articles/PMC2185930
http://europepmc.org/articles/PMC2185930