Use of platelet inhibitors for digital ulcers related to systemic sclerosis: EUSTAR study on derivation and validation of the DU-VASC model

Autor: Alexandru Garaiman 1, Klaus Steigmiller 2, Catherine Gebhard 3, Carina Mihai 1, Rucsandra Dobrota 1, Cosimo Bruni 4, Marco Matucci-Cerinic 5, Joerg Henes 6, Jeska de Vries-Bouwstra 7, Vanessa Smith 8, Andrea Doria 9, Yannick Allanore 10, Lorenzo Dagna 11, Branimir Anić 12, Carlomaurizio Montecucco 13, Otylia Kowal-Bielecka 14, Mickael Martin 15, Yoshiya Tanaka 16, Anna-Maria Hoffmann-Vold 17, Ulrike Held 2, Oliver Distler 1, Mike Oliver Becker 1, EUSTAR Silvia Bellando Randone, Gemma Lepri, Ulrich Walker, Florenzo Iannone, Suzana Jordan, Radim Becvar, Ewa Gindzienska-Sieskiewicz, Katarzyna Karaszewska, Maurizio Cutolo, Giovanna Cuomo, Elise Siegert, Simona Rednic, Jérome Avouac, Carole Desbas, Roberto Caporali, Lorenzo Cavagna, Patricia E Carreira, Srdan Novak, László Czirják, Michele Iudici, Eugene J Kucharz, Elisabetta Zanatta, Bernard Coleiro, Gianluca Moroncini, Dominique Farge Bancel, Paolo Airò, Roger Hesselstr, Mislav Radic, Alexandra Balbir-Gurman, Nicolas Hunzelmann, Raffaele Pellerito, Alessandro Giollo, Jadranka Morovic-Vergles, Christopher Denton, Nemanja Damjanov, Ann-Christian Pecher, Vera Ortiz Santamaria, Stefan Heitmann, Dorota Krasowska, Paul Hasler, Ivan Foeldvari, Maria João Salvador, Bojana Stamenkovic, Carlo Francesco Selmi, Lidia P Ananieva, Ariane Herrick, Ulf Müller-Ladner, Raffaele De Palma, Merete Engelhart, Gabriela Szücs, Carlos de la Puente, Øyvind Midtvedt, Torhild Garen, Håvard Fretheim, Eric Hachulla, Valeria Riccieri, Ruxandra Maria Ionescu, Ana Maria Gheorghiu, Cord Sunderkötter, Jörg Distler, Francesca Ingegnoli, Luc Mouthon, Francesco Paolo Cantatore, Susanne Ullman, Maria Rosa Pozzi, Kilian Eyerich, Piotr Wiland, Marie Vanthuyne, Juan Jose Alegre-Sancho, Kristine Herrmann, Ellen De Langhe, Marko Baresic, Miroslav Mayer, Sule Yavuz, Brigitte Granel, Carolina de Souza Müller, Svetlana Agachi, Simon Stebbings, D'Alessandro Mathieu, Alessandra Vacca, Kamal Solanki, Douglas Veale, Esthela Loyo, Carmen Tineo, Mengtao Li, Edoardo Rosato, Fahrettin Oksel, Figen Yargucu, Cristina-Mihaela Tanaseanu, Rosario Foti, Codrina Ancuta, Britta Maurer, Jacob van Laar, Marzena Olesinska, Cristiane Kayser, Nihal Fathi, Paloma García de la Peña Lefebvre, Jorge Juan Gonzalez Martin, Jean Sibilia, Ira Litinsky, Francesco Del Galdo, Lesley Ann Saketkoo, Eduardo Kerzberg, Washington Bianch, Breno Valdetaro Bianchi, Ivan Castellví, Massimiliano Limonta, Doron Rimar, Maura Couto, François Spertini, Antonella Marcoccia, Sarah Kahl, Ivien M Hsu, Thierry Martin, Sergey Moiseev, Pavel Novikov, Lorinda S Chung, Tim Schmeiser, Dominik Majewski, Zbigniew Zdrojewski, Julia Martínez-Barrio, Vera Bernardino, Gabriela Riemekasten, Yair Levy, Elena Rezus, Omer Nuri Pamuk, Piercarlo Sarzi Puttini, Hadi Poormoghim, Ina Kötter, Francis Gaches, Laura Belloli, Petros Sfikakis, Daniel Furst, Ana-Maria Ramazan, H U Scherer, Tom W J Huizinga, Marie-Elise Truchetet, Alain Lescoat, Giacomo De Luca, Corrado Campochiaro, J M van Laar, Lidia Rudnicka, Susana Oliveira, Fabiola Atzeni, Masataka Kuwana, Arsene Mekinian, Cédric L, Mathieu Puyade, Pascal Roblot, Satoshi Kubo, Yasuyuki Todoroki

Publikováno v: Rheumatology. OXFORD UNIV PRESS
Rheumatology

Objective To develop and validate the prognostic prediction model DU-VASC to assist the clinicians in decision-making regarding the use of platelet inhibitors (PIs) for the management of digital ulcers in patients with systemic sclerosis. Secondly, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1786f910ec1e71954a98f3c44716cc73
https://doi.org/10.1093/rheumatology/keac405

OP0091 EXPANSION OF MYELOPEROXIDASE (MPO)-SPECIFIC IgM B CELLS IN ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY (ANCA)-ASSOCIATED VASCULITIS

Autor: C. Wortel, R. van de Wetering, H. van Dooren, E. M. Stork, A. M. Bakker, A. S. Brehler, T. Kissel, S. Reijm, G. Stoeken-Rijsbergen, K. van Schie, A. Rutgers, L. A. Trouw, T. Huizinga, Y. K. O. Teng, C. van Kooten, P. Heeringa, R. Toes, H. U. Scherer

Publikováno v: Annals of the Rheumatic Diseases. 81:61.3-61

BackgroundANCA-associated vasculitides (AAV) are characterized by recurrent, chronic small vessel inflammation and deleterious organ damage. The main targets of ANCA are myeloperoxidase (MPO) and proteinase 3 (PR3). ANCA, B cells and the complement s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b7e9384774eb86884476abb5d4defbb
https://doi.org/10.1136/annrheumdis-2022-eular.5159

[Biomarkers and personalized medicine]

Autor: H U, Scherer, G-R, Burmester, T, Häupl

Publikováno v: Zeitschrift fur Rheumatologie. 72(1)

Biomarkers form the basis for patient stratification and the development of individualized treatment strategies. As the understanding of the pathophysiological processes underlying rheumatic diseases increases, novel biomarkers will become available

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d75ed4aa5551c52f30296e2db10e2692
https://pubmed.ncbi.nlm.nih.gov/23223890

[Polyarteritis nodosa - a 'classical' case]

Autor: H U, Scherer, F K H, van Landeghem, F, Buttgereit

Publikováno v: Zeitschrift fur Rheumatologie. 65(4)

Diagnosis of polyarteritis nodosa is often delayed due to the vast heterogeneity of initial clinical symptoms. The case presented shows the clinical image of the disease, leading from the first symptoms up to verification of the diagnosis by sural-ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::be7653fad8addd53cf90e1e6188f851b
https://pubmed.ncbi.nlm.nih.gov/16450153

Anti-citrullinated protein antibodies have a low avidity compared to antibodies against recall-antigens

Autor: P Suwannalai, H U Scherer, D van der Woude, A Ioan-Facsinay, C M J.-v. der Zijde, M J van Tol, T W J Huizinga, R E M Toes, L A Trouw

Publikováno v: Annals of the Rheumatic Diseases. 69:A7-A7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e93e5776c19d84f483a2599e2142e54
https://doi.org/10.1136/ard.2010.129577p