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Akademický článek
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Akademický článek
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Autor:
T.E.F. Abbott, M. Gooneratne, J. McNeill, A. Lee, D.Z.H. Levett, M.P.W. Grocott, M. Swart, N. MacDonald, T. Abbott, A. Raj, M. Rooms, M. Nicol, M. Koutra, S. Halworth, K. Wilkins, D. Nevin, E. Gaultry, J. Otto, D. Bell, M. Hardy, P. Prabhu, R. Ravishankar, J. Correia, C. Beilstein, K. Greaves, S. James, H. Tighe, J. Perks, J. Pennington, A. Pritchard, P. Moxon, K. Brown, J. Carlisle
Publikováno v:
British Journal of Anaesthesia. 120:475-483
Background Despite the increasing importance of cardiopulmonary exercise testing (CPET) for preoperative risk assessment, the reliability of CPET interpretation is unclear. We aimed to assess inter-observer reliability of preoperative CPET. Methods W
Autor:
McKenzie, Kawanna1 kawannamckenzie@yahoo.com, Arslan-Ari, Ismahan1 ismihanarslan@gmail.com
Publikováno v:
Educational Technology & Society. Oct2024, Vol. 27 Issue 4, p251-266. 16p.
Autor:
David A. Schwartz, Joseph Eiden, Stephen Tuck, Anne Kagey-Sobotka, Gary Van Nest, Peter S. Creticos, Kenji Takabayashi, H Tighe, Lawrence M. Lichtenstein, Hans L. Spiegelberg, Eyal Raz
Publikováno v:
Journal of Allergy and Clinical Immunology. 106:124-134
Background: Allergen immunotherapy is inconvenient and associated with the risk of anaphylaxis. Efforts to improve the safety of immunotherapy by means of chemical modification of allergens have not been successful because it greatly reduced their an
Autor:
Eyal Raz, H Tighe, Joseph Eiden, Jacques Corbeil, Kenji Takabayashi, Lucinda Beck, Robin Marsden, David A. Schwartz, Douglas D. Richman, Hans L. Spiegelberg
Publikováno v:
European Journal of Immunology. 30:1939-1947
Immunostimulatory DNA sequences (ISS) are a potent Th1 adjuvant. We hypothesized that conjugation of ISS to protein antigens would strongly enhance their immunogenicity because both antigen and adjuvant (ISS) would be delivered to the same locale/ant
Autor:
Maripat Corr, Klaus Warnatz, Diego Kyburz, Delphine J. Lee, Diana C. Brinson, H Tighe, Amila Von Damm, Michael Engelhart, Dennis A. Carson
Publikováno v:
Cellular Immunology. 191:69-73
Normal individuals do not express the high-affinity autoantibodies specific for self-IgG (rheumatoid factors, RF) that are commonly seen in rheumatoid arthritis patients. Studies of transgenic mice expressing a human IgM rheumatoid factor have shown
Publikováno v:
Pediatric Pulmonology. 27:118-121
The nature of the immune response (Th1/Th2) in mice to protein antigens or allergens was compared to that of immunization with pDNA encoding the same antigens. pDNA immunization induced a Th1 response and no IgE antibodies whereas the proteins induce
Publikováno v:
Allergy. 53:93-97
Autor:
William O. Weigle, Stephen M. Baird, Klaus Warnatz, Maripat Corr, H Tighe, Diana C. Brinson, Dennis A. Carson
Publikováno v:
Proceedings of the National Academy of Sciences. 94:646-651
Rheumatoid factor (RF) B cells proliferate during secondary immune responses to immune complexed antigen and antigen specific T cells, but higher affinity RFs are not detected except in patients with rheumatoid arthritis and other autoimmune diseases