Bayesian networks and imaging-derived phenotypes highlight the role of fat deposition in COVID-19 hospitalisation risk

Autor: T. Waddell, A. I. L. Namburete, P. Duckworth, N. Eichert, H. Thomaides-Brears, D. J. Cuthbertson, J. P. Despres, M. Brady

Publikováno v: Frontiers in Bioinformatics, Vol 3 (2023)

Objective: Obesity is a significant risk factor for adverse outcomes following coronavirus infection (COVID-19). However, BMI fails to capture differences in the body fat distribution, the critical driver of metabolic health. Conventional statistical

Externí odkaz: https://doaj.org/article/8b13b20ac7284ddb85cbc74952226f5c

Cardiac impairment in Long Covid 1-year post SARS-CoV-2 infection

Autor: A Roca-Fernandez, M Wamil, A Telford, V Carapella, A Borlotti, D Monteiro, H Thomaides-Brears, A Dennis, R Banerjee, M D Robson, G Y H Lip, S Bull, M Heightman, N Ntusi, A Banerjee

Publikováno v: European Heart Journal. 43

Background Long Covid is associated with multiple symptoms and impairment in multiple organs [1]. Cardiac impairment has been reported to varying degrees by varying methodologies in cross-sectional studies. Using cardiovascular magnetic resonance (CM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8fd6b7e1eedabcec450f8f86db96067
https://doi.org/10.1093/eurheartj/ehac544.219

Repeatability, Reproducibility, and Observer Variability of Cortical T1 Mapping for Renal Tissue Characterization.

Autor: Nowak M; Perspectum Ltd, Oxford, UK., Henningsson M; Perspectum Ltd, Oxford, UK., Davis T; Perspectum Ltd, Oxford, UK., Chowdhury N; Perspectum Ltd, Oxford, UK., Dennis A; Perspectum Ltd, Oxford, UK., Fernandes C; Perspectum Ltd, Oxford, UK., Thomaides Brears H; Perspectum Ltd, Oxford, UK., Robson MD; Perspectum Ltd, Oxford, UK.

Publikováno v: Journal of magnetic resonance imaging : JMRI [J Magn Reson Imaging] 2024 Oct 28. Date of Electronic Publication: 2024 Oct 28.

Quantitative Imaging Reveals Steatosis and Fibroinflammation in Multiple Organs in People With Type 2 Diabetes: A Real-World Study.

Autor: Diamond C; Perspectum, Ltd., Oxford, U.K., Pansini M; Perspectum, Ltd., Oxford, U.K.; Clinica Di Radiologia EOC, Istituto Di Imaging Della Svizzera Italiana, Ente Ospedaliero Cantonale, Lugano, Switzerland., Hamid A; Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, U.K., Eichert N; Perspectum, Ltd., Oxford, U.K.; Wellcome Centre for Integrative Neuroimaging, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, U.K., Pandya P; Perspectum, Inc., Dallas, TX., Ali SN; Royal Free London NHS Foundation Trust, London, U.K., Kemp GJ; Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, U.K., Thanabalasingham G; Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford University Hospitals NHS Foundation Trust, Oxford, U.K., Thomaides Brears H; Perspectum, Ltd., Oxford, U.K., Cuthbertson DJ; Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, U.K.; University Hospital Aintree, Liverpool University Hospitals NHS Foundation Trust, Liverpool, U.K.

Publikováno v: Diabetes [Diabetes] 2024 Aug 01; Vol. 73 (8), pp. 1285-1299.

Liver disease is a significant risk factor for cardiovascular outcomes - A UK Biobank study.

Autor: Roca-Fernandez A; Perspectum Ltd., Oxford, United Kingdom., Banerjee R; Perspectum Ltd., Oxford, United Kingdom; Oxford University Hospitals Foundation Trust, Oxford, United Kingdom., Thomaides-Brears H; Perspectum Ltd., Oxford, United Kingdom., Telford A; Perspectum Ltd., Oxford, United Kingdom., Sanyal A; Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University School of Medicine, Richmond, VA, United States., Neubauer S; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, United Kingdom., Nichols TE; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Raman B; Oxford University Hospitals Foundation Trust, Oxford, United Kingdom; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, United Kingdom., McCracken C; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, United Kingdom., Petersen SE; William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, UK; Health Data Research UK, London, UK; Alan Turing Institute, London, UK., Ntusi NA; Division of Cardiology, Department of Medicine, University of Cape Town and Groote Schuur, J46, Old Main Building, Main Road, Observatory, Cape Town, 7925, South Africa., Cuthbertson DJ; Department of Cardiovascular and Metabolic Medicine, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Lai M; Department of Medicine, Liver Centre, Beth Israel Deaconess Medical Centre, Harvard Medical School, 110 Francis Street, Suite 4A, Boston, USA., Dennis A; Perspectum Ltd., Oxford, United Kingdom., Banerjee A; University College London Hospitals National Health Service Trust, London, United Kingdom; Institute of Health Informatics, University College London, London, United Kingdom; Barts Health National Health Service Trust, The Royal London Hospital, London, United Kingdom. Electronic address: ami.banerjee@ucl.ac.uk.

Publikováno v: Journal of hepatology [J Hepatol] 2023 Nov; Vol. 79 (5), pp. 1085-1095. Date of Electronic Publication: 2023 Jun 20.