Zobrazeno 1 - 10
of 239
pro vyhledávání: '"H Terence, Cook"'
Autor:
Frederick W.K. Tam, James Tumlin, Jonathan Barratt, Brad H. Rovin, Ian S.D. Roberts, Candice Roufosse, H. Terence Cook, Gurjeet Bhangal, Alison L. Brown, Martin Busch, Fayaz Dudhiya, Anne-Marie Duliege, Donald J. Fraser, Daniel P. Gale, Chiu-Ching Huang, Ping-Chin Lai, Meng Lee, Esteban S. Masuda, Stephen P. McAdoo, Alexander R. Rosenkranz, Claudia Sommerer, Gere Sunder-Plassmann, Cheuk-Chun Szeto, Sydney C.W. Tang, Don E. Williamson, Lisa Willcocks, Volker Vielhauer, Min Jeong Kim, Leslie Todd, Hany Zayed, Sandra Tong-Starksen, Richard Lafayette
Publikováno v:
Kidney International Reports, Vol 8, Iss 12, Pp 2546-2556 (2023)
Introduction: We reported increased spleen tyrosine kinase (SYK) expression in kidney biopsies of patients with IgA nephropathy (IgAN) and that inhibition of SYK reduces inflammatory cytokines production from IgA stimulated mesangial cells. Methods:
Externí odkaz:
https://doaj.org/article/66982ca5bf66483cb14ee295eaf07526
Autor:
Shenzhen Tempest-Roe, Maria Prendecki, Stephen P. McAdoo, Candice Clarke, Anisha Tanna, Tabitha Turner-Stokes, Esteban S. Masuda, Michelle Willicombe, H. Terence Cook, Candice Roufosse, David Taube, Charles D. Pusey, Frederick W. K. Tam
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Antibody mediated rejection is a major cause of renal allograft loss. Circulating preformed donor specific antibodies (DSA) can result as a consequence of blood transfusion, pregnancy or prior transplantation. Current treatment strategies ar
Externí odkaz:
https://doaj.org/article/657abd7f4c754b5aa4ed59b73337583f
Autor:
Aikaterini Nikolopoulou, Isabel Huang-Doran, Stephen P. McAdoo, Megan E. Griffith, H. Terence Cook, Charles D. Pusey
Publikováno v:
Kidney International Reports, Vol 4, Iss 11, Pp 1577-1584 (2019)
Introduction: Membranous glomerulonephritis (MGN) is rarely associated with necrotizing and crescentic glomerulonephritis (NCGN). Methods: We report the clinical and pathologic findings in 15 patients with MGN and NCGN associated with anti-neutrophil
Externí odkaz:
https://doaj.org/article/de230865076a4f8ea45340f7efda6656
Autor:
Nicholas R. Medjeral-Thomas, Hilary Moffitt, Hannah J. Lomax-Browne, Nicholas Constantinou, Tom Cairns, H. Terence Cook, Matthew C. Pickering
Publikováno v:
Kidney International Reports, Vol 4, Iss 10, Pp 1387-1400 (2019)
Introduction: Therapeutic agents that target complement are increasingly available for glomerular diseases. However, the mechanisms linking glomerular complement deposition with inflammation and damage are incompletely understood. Complement factor H
Externí odkaz:
https://doaj.org/article/88639a1684f5461493008da5093936a6
Autor:
Aikaterini Nikolopoulou, Marie Condon, Tabitha Turner-Stokes, H. Terence Cook, Neill Duncan, Jack W. Galliford, Jeremy B. Levy, Liz Lightstone, Charles D. Pusey, Candice Roufosse, Thomas D. Cairns, Megan E. Griffith
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Tacrolimus (TAC) is effective in treating membranous nephropathy (MN); however relapses are frequent after treatment cessation. We conducted a randomised controlled trial to examine whether the addition of mycophenolate mofetil (M
Externí odkaz:
https://doaj.org/article/b42aec24ca99469f9ae73d6fe370b462
Autor:
Katherine M. Dominy, Michelle Willicombe, Tariq Al Johani, Hannah Beckwith, Dawn Goodall, Paul Brookes, H. Terence Cook, Tom Cairns, Adam McLean, Candice Roufosse
Publikováno v:
Kidney International Reports, Vol 4, Iss 1, Pp 148-158 (2019)
Introduction: Immunohistochemical staining for C4d in peritubular capillaries has been part of antibody-mediated rejection (AbMR) definition in the Banff Classification for Allograft Pathology since 2003. However, it has limited sensitivity and speci
Externí odkaz:
https://doaj.org/article/880cfddd007d4d088228bc0afb92e92a
Autor:
Nicholas R. Medjeral-Thomas, Anne Troldborg, Nicholas Constantinou, Hannah J. Lomax-Browne, Annette G. Hansen, Michelle Willicombe, Charles D. Pusey, H. Terence Cook, Steffen Thiel, Matthew C. Pickering
Publikováno v:
Kidney International Reports, Vol 3, Iss 2, Pp 426-438 (2018)
IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-deficient IgA1 and complement proteins and leads to renal impairment. Complement deposition through the alternative and lectin activation pathways is associated with renal
Externí odkaz:
https://doaj.org/article/343f738fd1b549c1931233d31f58310f
Publikováno v:
American Journal of Kidney Diseases. 80:416-421
Autor:
Hannah J. Lomax-Browne, Nicholas R. Medjeral-Thomas, Sean J. Barbour, Jack Gisby, Heedeok Han, Andrew S. Bomback, Fernando C. Fervenza, Thomas H. Cairns, Richard Szydlo, Sven-Jean Tan, Stephen D. Marks, Aoife M. Waters, Gerald B. Appel, Vivette D. D’Agati, Sanjeev Sethi, Cynthia C. Nast, Ingeborg Bajema, Charles E. Alpers, Agnes B. Fogo, Christoph Licht, Fadi Fakhouri, Daniel C. Cattran, James E. Peters, H. Terence Cook, Matthew C. Pickering
Publikováno v:
Clin J Am Soc Nephrol
Clinical Journal of the American Society of Nephrology, 17(7), 994-1007. AMER SOC NEPHROLOGY
Clinical Journal of the American Society of Nephrology, 17(7), 994-1007. AMER SOC NEPHROLOGY
Background and objectives: C3 glomerulopathy and idiopathic Ig-associated membranoproliferative GN are kidney diseases characterized by abnormal glomerular complement C3 deposition. These conditions are heterogeneous in outcome, but approximately 50%
Autor:
Marie Pereira, Tai-Di Chen, Norzawani Buang, Antoni Olona, Jeong-Hun Ko, Maria Prendecki, Ana S.H. Costa, Efterpi Nikitopoulou, Laura Tronci, Charles D. Pusey, H. Terence Cook, Stephen P. McAdoo, Christian Frezza, Jacques Behmoaras
Publikováno v:
Cell Reports, Vol 28, Iss 2, Pp 498-511.e5 (2019)
Summary: Iron is an essential metal that fine-tunes the innate immune response by regulating macrophage function, but an integrative view of transcriptional and metabolic responses to iron perturbation in macrophages is lacking. Here, we induced acut
Externí odkaz:
https://doaj.org/article/52934f4eeed3453cb2969714de777c3f