Zobrazeno 1 - 10
of 22
pro vyhledávání: '"H Tanasichuk"'
Autor:
D.S. Fulton, R.C. Urtasun, K.H. Shin, P.H.S. Geggie, H. Thomas, P.J. Muller, J. Moody, H. Tanasichuk, B. Mielke, E. Johnson, B. Curry
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 10:1709-1712
Multiple daily fractionated radiation therapy (MDF) may be more effective than conventionally fractionated radiation therapy (CF) in the treatment of malignant glioma. The hypoxic cell sensitizer misonidazole (MISO) could be more effective when emplo
Autor:
J D Miller, B Mielke, M L Feldstein, J Partington, O Agboola, D B Russell, H Tanasichuk, Raul C. Urtasun
Publikováno v:
British Journal of Cancer
As a continuation of a previous controlled trial using "high-dose" metronidazole as a specific sensitizer of hypoxic cells, we used a more efficient nitroimidazole derivative (misonidazole, MISO) in combination with higher doses of radiation in patie
Autor:
Edward S. Johnson, Paul J. Muller, Burnadette Curry, Raul C. Urtasun, Peter H.S. Geggie, Michael Feldstein, Harvy Thomas, Dorcus Fulton, Bruce Mielke, Kyu H. Shin, H. Tanasichuk
Publikováno v:
Cancer. 56:758-760
Various attempts have been made to improve the effectiveness of radiation in the treatment of cerebral malignant astrocytomas. A trend favoring multiple daily fractionated (MDF) radiation therapy over conventional single daily fractionated (CF) radia
Publikováno v:
Journal of neuro-oncology. 4(4)
CCNU chemotherapy prolongs survival of patients with primary brain tumor when given at the time of tumor progression following radiation therapy. Used as single agent, response rates of 30 to 80 per cent have been reported with median response durati
Autor:
D. Koziol, Raul C. Urtasun, R. Turner, O. Agboola, H R Rabin, H. Tanasichuk, J. Raleigh, Dorcas Fulton
Publikováno v:
International journal of radiation oncology, biology, physics. 8(3-4)
Although considerable laboratory in vitro and in vivo evidence is now available suggesting that misonidazole (MISO) enhances chemotherapy tumor responses, experience with human tumors is limited. Further, the mechanism of this enhancement is not defi
Autor:
K H, Shin, R C, Urtasun, D, Fulton, P H, Geggie, H, Tanasichuk, H, Thomas, P J, Muller, B, Curry, B, Mielke, E, Johnson
Publikováno v:
Cancer. 56(4)
Various attempts have been made to improve the effectiveness of radiation in the treatment of cerebral malignant astrocytomas. A trend favoring multiple daily fractionated (MDF) radiation therapy over conventional single daily fractionated (CF) radia
Publikováno v:
International journal of radiation oncology, biology, physics. 10(9)
Neurotoxicity induced by misonidazole (MISO) and desmethylmisonidazole (DMM) has become the dose limiting factor in clinical work. In 1981, we reported a preliminary study suggestive that Dexamethasone (DEXA) does have a protective effect against per
Autor:
D. Koziol, J. Raleigh, A.R. Turner, Raul C. Urtasun, O. Agboola, H. Tanasichuk, Dorcas Fulton
Publikováno v:
International journal of radiation oncology, biology, physics. 8(3-4)
With a view to modifying misonidazole (MISO) neurotoxicity, we initiated a randomized clinical study to assess a possible drug interaction and toxicity protection when dexamethasone (DXM) is administered concomittantly with MISO. The ongoing study co
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Akademický článek
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