Zobrazeno 1 - 3
of 3
pro vyhledávání: '"H T Wolfenden"'
Publikováno v:
Xenobiotica. 16:483-490
The 8-h urinary metabolic profiles of encainide and its oxidized metabolites, O-desmethyl- (ODE), 3-methoxy-O-desmethyl- (MODE), N-desmethyl- (NDE) and N, O-didesmethyl- (DDE) encainide were studied in a group of 112 normal Caucasians. Nine of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47a21e5ad71b302dd26e2878110daed
https://doi.org/10.3109/00498258609050253
https://doi.org/10.3109/00498258609050253
Autor:
Wade W Sutton, Robert H Bergstrand, Raymond L. Woosley, H T Wolfenden, Ted Wang, G. R. Avant, Dan M. Roden, Grant R. Wilkinson, Lyle A. Siddoway, Alastair J. J. Wood
Publikováno v:
Clinical Pharmacology and Therapeutics. 40:148-154
The antiarrhythmic agent encainide undergoes extensive first-pass hepatic metabolism after oral dosing. The active metabolites O-desmethylencainide and 3-methoxy-O-desmethylencainide are formed in subjects who are extensive metabolizers (EMs), a phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db34bcae12592a05e970c216558c717d
https://doi.org/10.1038/clpt.1986.155
https://doi.org/10.1038/clpt.1986.155
Autor:
Raymond L. Woosley, William J. Stone, H T Wolfenden, Ted Wang, Alastair J. J. Wood, Robert H Bergstrand, Dan M. Roden, Grant R. Wilkinson
Publikováno v:
Clinical pharmacology and therapeutics. 40(1)
The antiarrhythmic agent encainide undergoes extensive presystemic biotransformation to form O-desmethylencainide (ODE) and 3-methoxy-ODE (MODE) in subjects who exhibit the extensive metabolizer (EM) phenotype for debrisoquin 4-hydroxylation. These m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5fc2730135a9d78371f92fafc7d6fa
https://pubmed.ncbi.nlm.nih.gov/3087679
https://pubmed.ncbi.nlm.nih.gov/3087679