Zobrazeno 1 - 10
of 13
pro vyhledávání: '"H T Petrie"'
Publikováno v:
The Journal of Immunology. 157:4293-4296
Two types of T lymphocytes can be generated intrathymically, distinguishable by either TCR-gamma delta or -alpha beta surface expression. Regulation of the intrathymic divergence of these cells is unresolved, at least in part because thymically deriv
Autor:
J Wayne, H Suh, K A Sokol, H T Petrie, M Witmer-Pack, S Edelhoff, C M Disteche, M C Nussenzweig
Publikováno v:
The Journal of Immunology. 153:5491-5502
RAG-1 and RAG-2 are developmentally regulated genes that are essential for V(D)J recombination and lymphocyte development. Expression of RAG-1 and RAG-2 by thymocytes is normally limited to cells that have not completed selection. We have previously
Publikováno v:
The Journal of Immunology. 151:29-37
In this report, we describe the isolation of a unique subpopulation of CD7+ cells from human fetal blood. Umbilical cord blood was first immuno-rosette-depleted using T cell, B cell, granulocyte, and macrophage markers to isolate a Lin- population. T
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(9)
Proliferation and cell death are tightly linked fates during cell and tissue differentiation. In the past few years, it has been shown that Bcl-2 exhibits a potent cell cycle inhibitory effect, in addition to its better known role in the antagonism o
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(5)
Development of the alphabeta and gammadelta T cell lineages is dependent upon the rearrangement and expression of the TCRalpha and beta or gamma and delta genes, respectively. Although the timing and sequence of rearrangements of the TCRalpha and TCR
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 157(10)
Two types of T lymphocytes can be generated intrathymically, distinguishable by either TCR-gamma delta or -alpha beta surface expression. Regulation of the intrathymic divergence of these cells is unresolved, at least in part because thymically deriv
Publikováno v:
Immunity. 2(6)
Using a quantitative multiprobe Southern blot analysis, we demonstrate the surprising result that a significant proportion of alpha beta T cells and thymocytes retain T cell receptor delta locus sequences. A substantial portion of the retained delta
Autor:
J, Wayne, H, Suh, K A, Sokol, H T, Petrie, M, Witmer-Pack, S, Edelhoff, C M, Disteche, M C, Nussenzweig
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 153(12)
RAG-1 and RAG-2 are developmentally regulated genes that are essential for V(D)J recombination and lymphocyte development. Expression of RAG-1 and RAG-2 by thymocytes is normally limited to cells that have not completed selection. We have previously
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(1)
In this report, we describe the isolation of a unique subpopulation of CD7+ cells from human fetal blood. Umbilical cord blood was first immuno-rosette-depleted using T cell, B cell, granulocyte, and macrophage markers to isolate a Lin- population. T
Publikováno v:
European journal of immunology. 22(8)
Two types of T lymphocytes, distinguishable by their surface expression of either the gamma delta or the alpha beta T cell receptor (TcR) for antigen, populate the periphery in the adult. In addition, immature precursors of both T cell types can be f