Zobrazeno 1 - 10
of 53
pro vyhledávání: '"H T Cook"'
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Necrotizing glomerular lesions are a feature of severe glomerulonephritis. Unlike apoptosis, cellular necrosis has the potential to release damage-associated proteins into the microenvironment, thereby potentiating inflammation. U
Externí odkaz:
https://doaj.org/article/e83b3abd8b32493f8e6813f614c818a1
Publikováno v:
BMC Nephrology
Background Necrotizing glomerular lesions are a feature of severe glomerulonephritis. Unlike apoptosis, cellular necrosis has the potential to release damage-associated proteins into the microenvironment, thereby potentiating inflammation. Until rece
Autor:
H. T. Cook, Kathy Dominy, Kakit Chan, Jack Galliford, Candice Roufosse, David Taube, Paul Brookes, H. de Kort, Adam McLean, Eva Santos-Nunez, Michelle Willicombe
Publikováno v:
American Journal of Transplantation, 13(2), 485-492
In renal transplant patients with de novo donor-specific antibodies (dnDSA) we studied the value of microcirculation inflammation (MI; defined by the addition of glomerulitis (g) and peritubular capillaritis (ptc) scores) to assess long-term graft su
Autor:
Alan D. Salama, Maria Prendecki, Neill Duncan, David Taube, Tom Cairns, Anisha Tanna, Frederick W.K. Tam, Charles D. Pusey, H. T. Cook, Damien Ashby
Publikováno v:
Clinical Kidney Journal
Background: There are no prospective randomized controlled trials describing the outcome of acute interstitial nephritis (AIN) treated with steroids, and retrospective studies are limited. Methods: We identified adult patients with a diagnosis of AIN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcec13e9b1a80206b3c7ac2ee2da0f4b
http://hdl.handle.net/10044/1/48020
http://hdl.handle.net/10044/1/48020
Autor:
Matthew C. Pickering, A. R. Koskinen, T. S. Jokiranta, Zhu-Zhu Cheng, K. Kairemo, Seppo Meri, Taru Meri, H. T. Cook
Publikováno v:
Scandinavian Journal of Immunology. 88:e12671
Factor H is an important regulator of complement activation in plasma and on cell surfaces in both humans and mice. If FH function is compromised, inappropriate complement activation on self-surfaces can have disastrous effects as seen in the kidney
Publikováno v:
Clinical and Experimental Dermatology. 34:e577-e580
We report the case of a 59-year-old woman who presented with a persistent papular and nodular cutaneous eruption and new-onset asthma, with normal renal function but persistent haematuria and proteinuria. Investigations revealed eosinophilia, both an
Autor:
Rosemary Jeffery, Nicholas A. Wright, Tim Hunt, J. Rao, William R. Otto, R. Poulsom, H. T. Cook, M. R. Alison, T.-C. Fang
Publikováno v:
Cell Proliferation. 41:575-591
Objective: Our previous studies have demonstrated that endogenous bone marrow cells (BMCs) contribute to renal tubular regeneration after acute tubular injury. The aim of this study was to examine which fraction of BMCs, haematopoietic lineage marrow
Autor:
William R. Otto, Tim Hunt, Rosemary Jeffery, T.-C. Fang, R. Poulsom, M. R. Alison, H. T. Cook, Nicholas A. Wright
Publikováno v:
Cell Proliferation. 41:592-606
Objective: Various studies have shown that bone marrow stem cells can rescue mice from acute renal tubular damage under a conditioning advantage (irradiation or cisplatin treatment) favouring donor cell engraftment and regeneration; however, it is no
Autor:
H. T. Cook, Candice Roufosse
Publikováno v:
Nephron Experimental Nephrology. 109:e39-e45
The role of embryonal or adult stem cells, in particular bone marrow (BM)-derived stem cells, in regenerating the kidney after injury has been the subject of intensive investigation. BM-derived stem cells have been shown to give rise to small numbers
Publikováno v:
International Journal of Experimental Pathology. 78:33-41
Fibroblasts act as the effector cells of the fibrotic response via production of collagen. In an attempt to understand the regulation of fibroblasts from areas of active human tissue fibrosis, we have developed an ex vivo model in which biopsies of s