Zobrazeno 1 - 10
of 286
pro vyhledávání: '"H T, Lynch"'
Autor:
H. T. Lynch
Publikováno v:
Archives of Internal Medicine. 153:1979-1987
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e8ed20dc0c2932ae75b8375af21deb9
https://doi.org/10.1001/archinte.153.17.1979
https://doi.org/10.1001/archinte.153.17.1979
Publikováno v:
Cancer. 66:502-508
A transformation in the composition of colonic glycoconjugates has been described in adenomas, carcinomas, and certain premalignant conditions. These changes have been detected histochemically by the labeling patterns of fluorescein-conjugated lectin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::799066c4e2260e94bd6ef302bbd3a9b6
https://doi.org/10.1002/1097-0142(19900801)66:3<502::aid-cncr2820660317>3.0.co
https://doi.org/10.1002/1097-0142(19900801)66:3<502::aid-cncr2820660317>3.0.co
Autor:
P, Watson, H T, Lynch
Publikováno v:
Familial cancer. 1(1)
Optimally accurate and valid estimates of cancer risk in genetically- defined subgroups requires population-based research. For rare genetic traits, very large studies are needed. Such is the case in hereditary nonpolyposis colorectal cancer syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1c0c87163993d4488f8dd5666145b73
https://pubmed.ncbi.nlm.nih.gov/14574017
https://pubmed.ncbi.nlm.nih.gov/14574017
Autor:
R A, Mosquera, H T, Lynch
Publikováno v:
Boletin de la Asociacion Medica de Puerto Rico. 93(1-12)
Colorectal cancer (CRC) incidence in Puerto Rico has increased prodigiously since incidence figures were first recorded in 1950. Implications for hereditary nonpolyposis colorectal cancer (HNPCC) in concert with this increased CRC incidence are discu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77e2521bbc9fa24c6f1944442942d265
https://pubmed.ncbi.nlm.nih.gov/12755068
https://pubmed.ncbi.nlm.nih.gov/12755068
Autor:
M G, Sayed, A F, Ahmed, J R, Ringold, M E, Anderson, J L, Bair, F A, Mitros, H T, Lynch, S T, Tinley, G M, Petersen, F M, Giardiello, B, Vogelstein, J R, Howe
Publikováno v:
Annals of surgical oncology. 9(9)
Juvenile polyposis (JP) is an inherited condition predisposing to upper gastrointestinal (UGI) polyps and colorectal cancer. Two genes are known to predispose to JP, SMAD4 and bone morphogenetic protein receptor type 1A (BMPR1A). The object of this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::220d9c76538c999d13bf6f7c401a5fb6
https://pubmed.ncbi.nlm.nih.gov/12417513
https://pubmed.ncbi.nlm.nih.gov/12417513
Autor:
H, Moriyama, H, Sasamoto, T, Kambara, N, Matsubara, M, Ikeda, S, Baba, S J, Meltzer, H T, Lynch, K, Shimizu, N, Tanaka
Publikováno v:
Journal of experimentalclinical cancer research : CR. 21(2)
Defects in the DNA mismatch repair function are known to cause microsatellite instability (MSI) in hereditary non-polyposis colorectal cancer (HNPCC) as well as in a subset of sporadic colorectal cancer (CRC). We previously reported that the E2F-4 ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::344068d13c81ec2a647ce70d90d6d832
https://pubmed.ncbi.nlm.nih.gov/12148576
https://pubmed.ncbi.nlm.nih.gov/12148576
Publikováno v:
Digestive diseases and sciences. 46(11)
Our purpose is to focus attention on the cancer family history, coupled with an understanding of the natural history and extracolonic tumor spectrum of familial adenomatous polyposis (FAP), through a family study. This family report provides an examp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3be9a8349b0b9d84275d348549fb9111
https://pubmed.ncbi.nlm.nih.gov/11713930
https://pubmed.ncbi.nlm.nih.gov/11713930
Autor:
A, Stella, A, Wagner, K, Shito, S M, Lipkin, P, Watson, G, Guanti, H T, Lynch, R, Fodde, B, Liu
Publikováno v:
Cancer research. 61(19)
Germline mutations in the DNA mismatch repair genes MSH2 and MLH1 are responsible for the majority of hereditary nonpolyposis colorectal cancer (HNPCC) families. A common mutation mechanism is to disrupt MLH1 and MSH2 mRNA splicing. The disruption cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e81c86014831d3028c8a12e6ac345d68
https://pubmed.ncbi.nlm.nih.gov/11585727
https://pubmed.ncbi.nlm.nih.gov/11585727
Autor:
T R, Rebbeck, Y, Wang, P W, Kantoff, K, Krithivas, S L, Neuhausen, A K, Godwin, M B, Daly, S A, Narod, J S, Brunet, D, Vesprini, J E, Garber, H T, Lynch, B L, Weber, M, Brown
Publikováno v:
Cancer research. 61(14)
Women who have inherited a germ-line mutation in the BRCA1 or BRCA2 (BRCA1/2) genes have a greatly increased risk of developing breast cancer compared with the general population. However, there is also substantial interindividual variability in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44238e0716db1062633b0e380d71f542
https://pubmed.ncbi.nlm.nih.gov/11454686
https://pubmed.ncbi.nlm.nih.gov/11454686