Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein

Autor: Dorota Rowczenio, Maria Stensland, Gustavo A. de Souza, Erik H. Strøm, Janet A. Gilbertson, Graham Taylor, Nigel Rendell, Shane Minogue, Yvonne A. Efebera, Helen J. Lachmann, Ashutosh D. Wechalekar, Philip N. Hawkins, Ketil R. Heimdal, Kristian Selvig, Inger K. Lægreid, Nathalie Demoulin, Selda Aydin, Julian D. Gillmore, Tale N. Wien

Publikováno v: Kidney International Reports, Vol 2, Iss 3, Pp 461-469 (2017)

Fibrinogen A alpha chain amyloidosis is an autosomal dominant disease associated with mutations in the fibrinogen A alpha chain (FGA) gene, and it is the most common cause of hereditary renal amyloidosis in the UK. Patients typically present with kid

Externí odkaz: https://doaj.org/article/eafc8316f25e41acb96af87f66ab9d68

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Lecithin:cholesterol acyltransferase: symposium on 50 years of biomedical research from its discovery to latest findings

Autor: Erik H. Strøm, Alan T. Remaley, Mingyue Zhou, Dominic S. Ng, Helena E. Miettinen, Ingrid Wiig, Jan Albert Kuivenhoven, John J.G. Tesmer, Carlos A.T.L. Sampaio, Kjetil Retterstøl, Laura Calabresi, Kelly A. Manthei, Bjørn Skeie, Bruno Eduardo Pedroso Balbo, Kaare R. Norum, Sotirios K. Karathanasis

Publikováno v: Journal of Lipid Research, 61(8), 1142-1149. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Journal of Lipid Research, Vol 61, Iss 8, Pp 1142-1149 (2020)
Journal of Lipid Research

LCAT converts free cholesterol to cholesteryl esters in the process of reverse cholesterol transport. Familial LCAT deficiency (FLD) is a genetic disease that was first described by Kaare R. Norum and Egil Gjone in 1967. This report is a summary from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1777729792af43281ba3ed6bd138094
https://research.rug.nl/en/publications/fd824db0-b663-4e08-b6e4-9e86a4ab06c1

Lupus nephritis: low urinary DNase I levels reflect loss of renal DNase I and may be utilized as a biomarker of disease progression

Autor: Dhivya Thiyagarajan, Gabriella Moroni, Gunnstein Bakland, Natalya Seredkina, Ole Petter Rekvig, Erik H. Strøm, Hallvard Holdaas, Pier Luigi Meroni, Gudrun E. Norby, Hege Lynum Pedersen, Kjersti Daae Horvei, Gro Østli Eilertsen

Publikováno v: The Journal of Pathology: Clinical Research. 4:193-203

Renal DNase I is lost in advanced stages of lupus nephritis. Here, we determined if loss of renal DNase I reflects a concurrent loss of urinary DNase I, and whether absence of urinary DNase I predicts disease progression. Mouse and human DNase I prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cb311dcd9360bd1579f3b1cc9c9d9fc
https://doi.org/10.1002/cjp2.99