Zobrazeno 1 - 10
of 128
pro vyhledávání: '"H Steven Wiley"'
Autor:
H Steven Wiley
Publikováno v:
eLife, Vol 7 (2018)
Extremely low numbers of active epidermal growth factor receptors are sufficient to drive tumor growth.
Externí odkaz:
https://doaj.org/article/70d5161f8f3146d087fbbef32ffbefa4
Autor:
Harish Shankaran, Danielle L Ippolito, William B Chrisler, Haluk Resat, Nikki Bollinger, Lee K Opresko, H Steven Wiley
Publikováno v:
Molecular Systems Biology, Vol 5, Iss 1, Pp 1-13 (2009)
Abstract Although the ERK pathway has a central role in the response of cells to growth factors, its regulatory structure and dynamics are incompletely understood. To investigate ERK activation in real time, we expressed an ERK–GFP fusion protein i
Externí odkaz:
https://doaj.org/article/c52acfba56f342109a0f767a607cf83d
Autor:
Becky M Hess, Junfeng Xue, Lye Meng Markillie, Ronald C Taylor, H Steven Wiley, Birgitte K Ahring, Bryan Linggi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66104 (2013)
The isoprenoid pathway converts pyruvate to isoprene and related isoprenoid compounds in plants and some bacteria. Currently, this pathway is of great interest because of the critical role that isoprenoids play in basic cellular processes, as well as
Externí odkaz:
https://doaj.org/article/ddc1051b6e064f62959a32ff7c5a4898
Autor:
Katrina M Waters, Tao Liu, Ryan D Quesenberry, Alan R Willse, Somnath Bandyopadhyay, Loel E Kathmann, Thomas J Weber, Richard D Smith, H Steven Wiley, Brian D Thrall
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34515 (2012)
To understand how integration of multiple data types can help decipher cellular responses at the systems level, we analyzed the mitogenic response of human mammary epithelial cells to epidermal growth factor (EGF) using whole genome microarrays, mass
Externí odkaz:
https://doaj.org/article/9e28a2d1d50745789d5ed96c8971fda6
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 6, p e101 (2007)
Receptors constitute the interface of cells to their external environment. These molecules bind specific ligands involved in multiple processes, such as signal transduction and nutrient transport. Although a variety of cell surface receptors undergo
Externí odkaz:
https://doaj.org/article/24c7c9b4d3344df3a8b8865eb19fde1b
Autor:
Chia-Feng Tsai, Pengfei Zhang, David Scholten, Kendall Martin, Yi-Ting Wang, Rui Zhao, William B. Chrisler, Dhwani B. Patel, Maowei Dou, Yuzhi Jia, Carolina Reduzzi, Xia Liu, Ronald J. Moore, Kristin E. Burnum-Johnson, Miao-Hsia Lin, Chuan-Chih Hsu, Jon M. Jacobs, Jacob Kagan, Sudhir Srivastava, Karin D. Rodland, H. Steven Wiley, Wei-Jun Qian, Richard D. Smith, Ying Zhu, Massimo Cristofanilli, Tao Liu, Huiping Liu, Tujin Shi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Tsai, Zhang, Scholten et al. develop a surfactant- assisted one-pot sample preparation coupled with mass spectrometry method (SOP-MS) for label-free global single-cell proteomics. This method allows researchers to measure hundreds of proteins from si
Externí odkaz:
https://doaj.org/article/a689739f342a49b381b96ffab619ff1e
Autor:
Prakash Kulkarni, H. Steven Wiley, Herbert Levine, Herbert Sauro, Alexander Anderson, Stephen T.C. Wong, Aaron S. Meyer, Puneeth Iyengar, Kevin Corlette, Kristin Swanson, Atish Mohanty, Supriyo Bhattacharya, Amit Patel, Vinay Jain, Ravi Salgia
Publikováno v:
Trends in Cancer. 9:185-187
Publikováno v:
Curr Pathobiol Rep
PURPOSE OF REVIEW: Signaling pathways serve to communicate information about extracellular conditions into the cell, to both the nucleus and cytoplasmic processes to control cell responses. Genetic mutations in signaling network components are freque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b161dd54ead719b9d4d1264d75de6cc4
https://europepmc.org/articles/PMC10035447/
https://europepmc.org/articles/PMC10035447/
Autor:
Rui Zhao, H. Steven Wiley, Kristin E. Burnum-Johnson, Yuzhi Jia, Ying Zhu, David Scholten, Tao Liu, Karin D. Rodland, Jacob Kagan, Sudhir Srivastava, Miao-Hsia Lin, Wei-Jun Qian, Richard D. Smith, Yi-Ting Wang, Huiping Liu, Massimo Cristofanilli, Pengfei Zhang, William B. Chrisler, Maowei Dou, Kendall Martin, Xia Liu, Chuan-Chih Hsu, Dhwani Patel, Carolina Reduzzi, Jon M. Jacobs, Tujin Shi, Ronald J. Moore, Chia-Feng Tsai
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology
Communications Biology
Large numbers of cells are generally required for quantitative global proteome profiling due to surface adsorption losses associated with sample processing. Such bulk measurement obscures important cell-to-cell variability (cell heterogeneity) and ma
Autor:
Kendall Martin, Jessica L. Flesher, Rui Zhao, Klemens J. Hertel, Chia-Feng Tsai, Amber N Habowski, Yongsheng Shi, Anand K. Ganesan, Marian L. Waterman, Tujin Shi, Robert Edwards, H. Steven Wiley, Jennifer M. Bates
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-17 (2020)
Communications biology, vol 3, iss 1
Communications Biology
Communications biology, vol 3, iss 1
Communications Biology
Intestinal stem cells are non-quiescent, dividing epithelial cells that rapidly differentiate into progenitor cells of the absorptive and secretory cell lineages. The kinetics of this process is rapid such that the epithelium is replaced weekly. To d