Zobrazeno 1 - 10
of 2 962
pro vyhledávání: '"H Stern"'
Autor:
Lori A. Birder, Amanda Wolf-Johnston, Vladimir Ritov, Joel N. H. Stern, Robert Moldwin, Hann-Chorng Kuo, Edwin K. Jackson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Chronic visceral pain disorders, such as interstitial cystitis/bladder pain syndrome (IC/BPS), are difficult to treat, and therapies are limited in number and efficacy. Emerging evidence suggests that alterations in the enzyme purine nucleos
Externí odkaz:
https://doaj.org/article/4256ad94067c49c1a406b15a9d3f0194
Publikováno v:
Ecosphere, Vol 15, Iss 4, Pp n/a-n/a (2024)
Abstract Polar bears (Ursus maritimus) depend on sea ice to hunt their ice‐associated prey. However, climate‐induced sea ice loss is leading to changes in space‐use strategies of polar bears, with bears in some subpopulations spending more time
Externí odkaz:
https://doaj.org/article/466a0409317f423f8f351a4923554769
Autor:
Taylor M. Martinez, Hallie R. Wachsmuth, Rachel K. Meyer, Savanna N. Weninger, Adelina I. Lane, Archana Kangath, Gabriele Schiro, Daniel Laubitz, Jennifer H. Stern, Frank A. Duca
Publikováno v:
Nutrition & Metabolism, Vol 20, Iss 1, Pp 1-20 (2023)
Abstract Background The gut microbiome is a salient contributor to the development of obesity, and diet is the greatest modifier of the gut microbiome, which highlights the need to better understand how specific diets alter the gut microbiota to impa
Externí odkaz:
https://doaj.org/article/3c058da9c52d406fae9ccc5d926f798b
Key Techniques in Orthopaedic Surgery, 2nd Edition, by Steven Stern, Matthew Saltzman, and Christopher Bono provides a fully updated, easy-to-follow orthopaedics reference. The book encompasses a full spectrum of core orthopaedic procedures impacting
Autor:
Robert M. Moldwin, Vishaan Nursey, Oksana Yaskiv, Siddhartha Dalvi, Eric J. Macdonald, Michael Funaro, Chengliang Zhang, William DeGouveia, Marina Ruzimovsky, Horacio R. Rilo, Edmund J. Miller, Souhel Najjar, Inna Tabansky, Joel N. H. Stern
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-9 (2022)
Abstract Interstitial cystitis/bladder pain syndrome (IC/BPS) is a disorder characterized by bladder pain upon filling which severely affects quality of life. Clinical presentation can vary. Local inflammatory events typify the clinical presentation
Externí odkaz:
https://doaj.org/article/2bac7544f7fe49c9983322bd0b288494
Rare variants and HLA haplotypes associated in patients with neuromyelitis optica spectrum disorders
Autor:
Inna Tabansky, Akemi J. Tanaka, Jiayao Wang, Guanglan Zhang, Irena Dujmovic, Simone Mader, Venkatesh Jeganathan, Tracey DeAngelis, Michael Funaro, Asaff Harel, Mark Messina, Maya Shabbir, Vishaan Nursey, William DeGouvia, Micheline Laurent, Karen Blitz, Peter Jindra, Mark Gudesblatt, Regeneron Genetics Center, Alejandra King, Jelena Drulovic, Edmond Yunis, Vladimir Brusic, Yufeng Shen, Derin B. Keskin, Souhel Najjar, Joel N. H. Stern
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neuromyelitis optica spectrum disorders (NMOSD) are rare, debilitating autoimmune diseases of the central nervous system. Many NMOSD patients have antibodies to Aquaporin-4 (AQP4). Prior studies show associations of NMOSD with individual Human Leukoc
Externí odkaz:
https://doaj.org/article/0949e2708c71481fbc1c38c531d3cb15
Autor:
Jacqueline L. Beaudry, Kiran Deep Kaur, Elodie M. Varin, Laurie L. Baggio, Xiemin Cao, Erin E. Mulvihill, Jennifer H. Stern, Jonathan E. Campbell, Phillip E. Scherer, Daniel J. Drucker
Publikováno v:
Molecular Metabolism, Vol 22, Iss , Pp 37-48 (2019)
Objective: Administration of glucagon (GCG) or GCG-containing co-agonists reduces body weight and increases energy expenditure. These actions appear to be transduced by multiple direct and indirect GCG receptor (GCGR)-dependent mechanisms. Although t
Externí odkaz:
https://doaj.org/article/34b08743c20a4fa3babce0d5ea0b6b24
Autor:
Inna Tabansky, Derin B. Keskin, Deepika Watts, Cathleen Petzold, Michael Funaro, Warren Sands, Paul Wright, Edmond J. Yunis, Souhel Najjar, Betty Diamond, Yonghao Cao, David Mooney, Karsten Kretschmer, Joel N. H. Stern
Publikováno v:
Molecular Medicine, Vol 24, Iss 1, Pp 1-13 (2018)
Abstract Background Dendritic cells (DC) induce adaptive responses against foreign antigens, and play an essential role in maintaining peripheral tolerance to self-antigens. Therefore they are involved in preventing fatal autoimmunity. Selective deli
Externí odkaz:
https://doaj.org/article/359e3efd2cda48baa3c0a5c369963f74
Autor:
A. Schrader, G. Crispatzu, S. Oberbeck, P. Mayer, S. Pützer, J. von Jan, E. Vasyutina, K. Warner, N. Weit, N. Pflug, T. Braun, E. I. Andersson, B. Yadav, A. Riabinska, B. Maurer, M. S. Ventura Ferreira, F. Beier, J. Altmüller, M. Lanasa, C. D. Herling, T. Haferlach, S. Stilgenbauer, G. Hopfinger, M. Peifer, T. H. Brümmendorf, P. Nürnberg, K. S. J. Elenitoba-Johnson, S. Zha, M. Hallek, R. Moriggl, H. C. Reinhardt, M.-H. Stern, S. Mustjoki, S. Newrzela, P. Frommolt, M. Herling
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-22 (2018)
T-cell prolymphocytic leukemia (T-PLL) is a rare malignancy with a poor prognosis. Here, the authors investigate the genomic landscape, gene expression profiles and functional mechanisms in 111 patients, highlighting TCL1 overexpression and ATM aberr
Externí odkaz:
https://doaj.org/article/27f303840c0c4d6e8ca4ef99b0371076
Autor:
Emily C. Peters, Luke Safayan, Tyler J. Marx, Emily Ngu, Anastasiia Vasileva, India Zappia, William H. Powell, Frank A. Duca, Jennifer H. Stern
Publikováno v:
Biogerontology. 23:741-755
Chronic calorie restriction (CR) results in lengthened lifespan and reduced disease risk. Many previous studies have implemented 30–40% calorie restriction to investigate these benefits. The goal of our study was to investigate the effects of calor