Interplay of ribosomal DNA loci in nucleolar dominance: dominant NORs are up-regulated by chromatin dynamics in the wheat-rye system.

Autor: Manuela Silva, H Sofia Pereira, Miguel Bento, Ana Paula Santos, Peter Shaw, Margarida Delgado, Nuno Neves, Wanda Viegas

Publikováno v: PLoS ONE, Vol 3, Iss 12, p e3824 (2008)

BACKGROUND: Chromatin organizational and topological plasticity, and its functions in gene expression regulation, have been strongly revealed by the analysis of nucleolar dominance in hybrids and polyploids where one parental set of ribosomal RNA (rD

Externí odkaz: https://doaj.org/article/0cd8317d58af4eeaafb844f100938c02

Bisphenol A at concentrations found in human serum induces aneugenic effects in endothelial cells

Autor: Edna Ribeiro-Varandas, H. Sofia Pereira, Margarida Delgado, Wanda Viegas

Publikováno v: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 751:27-33

Bisphenol A (BPA) is an endocrine disrupting chemical to which humans are exposed. Continuous environmental exposure to BPA leads to its detection in the majority of individuals from developed countries, with serum concentrations ranging from 0.5 to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36524c393149059ce751344aaa9ef86c
https://doi.org/10.1016/j.mrgentox.2012.10.007

Bisphenol A alters transcript levels of biomarker genes for Major Depressive Disorder in vascular endothelial cells and colon cancer cells

Autor: H. Sofia Pereira, Wanda Viegas, Edna Ribeiro-Varandas, Margarida Delgado

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Bisphenol A (BPA) is capable of mimicking endogenous hormones with potential consequences for human health and BPA exposure has been associated with several human diseases including neuropsychiatric disorders. Here, quantitative Real-Time Polymerase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec161b518bf080c4c7ae0b45268737f
https://pubmed.ncbi.nlm.nih.gov/27010169

Bisphenol A disrupts transcription and decreases viability in aging vascular endothelial cells

Autor: Edna Ribeiro-Varandas, Luisa Brito, Margarida Delgado, Sara Monteiro, Elsa Neves, Ricardo B. Ferreira, Wanda Viegas, H. Sofia Pereira

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 15, Iss 9, Pp 15791-15805 (2014)
International Journal of Molecular Sciences; Volume 15; Issue 9; Pages: 15791-15805

Bisphenol A (BPA) is a widely utilized endocrine disruptor capable of mimicking endogenous hormones, employed in the manufacture of numerous consumer products, thereby interfering with physiological cellular functions. Recent research has shown that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105e1754e13af05831ba9a6bb206ec27
https://pubmed.ncbi.nlm.nih.gov/25207595

Rye Bs disclose ancestral sequences in cereal genomes with a potential role in gametophyte chromatid segregation

Autor: Augusta Barão, Ana D. Caperta, Wanda Viegas, Margarida Delgado, João Almeida Rocha, H. Sofia Pereira

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Research Article Two sequence families, E3900 and D1100, are amplified on the subtelomeric domain of the long arm of rye B chromosomes, the region that controls its drive mechanism. In this work, polymerase chain reaction (PCR) with a number of prime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c81ad386563f82ba5afdd8d1a2a047