Zobrazeno 1 - 10
of 4 591
pro vyhledávání: '"H Snyder"'
Autor:
Scott H. Snyder, Patricia A. Vignaux, Mustafa Kemal Ozalp, Jacob Gerlach, Ana C. Puhl, Thomas R. Lane, John Corbett, Fabio Urbina, Sean Ekins
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Recent advances in machine learning (ML) have led to newer model architectures including transformers (large language models, LLMs) showing state of the art results in text generation and image analysis as well as few-shot learning (FSLC) mo
Externí odkaz:
https://doaj.org/article/35dfdbecd04240859dca01d619069e05
Autor:
Robin Roychaudhuri, Timothy West, Soumyaroop Bhattacharya, Harry G. Saavedra, Hangnoh Lee, Lauren Albacarys, Moataz M. Gadalla, Mario Amzel, Peixin Yang, Solomon H. Snyder
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102043- (2024)
Background: D-amino acids are being recognized as important molecules in mammals with function. This is a first identification of endogenous D-cysteine in mammalian pancreas. Methods: Using a novel stereospecific bioluminescent assay, chiral chromato
Externí odkaz:
https://doaj.org/article/c79de96ab4ab473197ca0a6ed59181fe
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114028- (2024)
Summary: Many studies infer the role of neurons by asking what information can be decoded from their activity or by observing the consequences of perturbing their activity. An alternative approach is to consider information flow between neurons. We a
Externí odkaz:
https://doaj.org/article/7808fb5b544b4d49968731622cf423fd
Autor:
Gregory H. Snyder
Essays in Christian Teachers in Second-Century Rome situate Christian teachers in the social and intellectual context of the Roman urban environment. The teaching and textual work of well-known figures such as Marcion, Justin, Valentinus, and Tatian
Autor:
Richa Tyagi, Suwarna Chakraborty, Sunil Jamuna Tripathi, Ik-Rak Jung, Sangwon F. Kim, Solomon H. Snyder, Bindu D. Paul
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107199- (2023)
Summary: Maintenance of redox balance plays central roles in a plethora of signaling processes. Although physiological levels of reactive oxygen and nitrogen species are crucial for functioning of certain signaling pathways, excessive production of f
Externí odkaz:
https://doaj.org/article/872d7538b9ac4ec9875a5b192c097dbe
Autor:
Luke Reilly, Evan R. Semenza, George Koshkaryan, Subrata Mishra, Sujan Chatterjee, Efrat Abramson, Pamela Mishra, Yoshitasu Sei, Stephen A. Wank, Mark Donowitz, Solomon H. Snyder, Prasun Guha
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106623- (2023)
Summary: Protein kinase B (AKT) is essential for cell survival, proliferation, and migration and has been associated with several diseases. Here, we demonstrate that inositol polyphosphate multikinase (IPMK’s) lipid kinase property drives AKT activ
Externí odkaz:
https://doaj.org/article/85571b9385264238a49f9bb930e9f354
Known for its natural beauty, Land Between the Lakes National Recreation Area is the largest inland peninsula in the United States. Consisting of 170,000 acres of forested and protected public land between Kentucky Lake (Tennessee River) and Lake Bar
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Though much research has characterized both the behavior and electrophysiology of spatial memory for single targets in non-human primates, we know much less about how multiple memoranda are handled. Multiple memoranda may interact in the brain, affec
Externí odkaz:
https://doaj.org/article/1cd299e3255d414eaa694e34de348a97
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Primates use their arms in complex ways, frequently involving coordination between the two arms. Here, the authors show that task-specific information is shared across the hemispheres in a frequency-specific manner, perhaps in service of bimanual coo
Externí odkaz:
https://doaj.org/article/c8f8ab5075bd4e4cabaf86367ec6c073