Zobrazeno 1 - 10
of 243
pro vyhledávání: '"H Seward"'
Autor:
Soohyun P. Kim, Avery H. Seward, Jean Garcia-Diaz, Nathalie Alekos, Nicole R. Gould, Susan Aja, Joseph P. Stains, Michael J. Wolfgang, Ryan C. Riddle
Publikováno v:
iScience, Vol 26, Iss 7, Pp 106999- (2023)
Summary: The nuclear receptor peroxisome proliferator activated receptor-γ (PPARγ) is a key contributor to metabolic function via its adipogenic and insulin-sensitizing functions, but it has negative effects on skeletal homeostasis. Here, we questi
Externí odkaz:
https://doaj.org/article/8130372e4d334e6aac79e1a1c9407456
Autor:
S. Allender, J. Hayward, S. Gupta, A. Sanigorski, S. Rana, H. Seward, S. Jacobs, S. Venkatesh
Publikováno v:
npj Digital Medicine, Vol 3, Iss 1, Pp 1-8 (2020)
Abstract Complex health problems require multi-strategy, multi-target interventions. We present a method that uses machine learning techniques to choose optimal interventions from a set of possible interventions within a case study aiming to increase
Externí odkaz:
https://doaj.org/article/b6b0855aabc046839faaf63965a08e6c
Autor:
Christopher H. Seward, Michael C. Saul, Joseph M. Troy, Payam Dibaeinia, Huimin Zhang, Saurabh Sinha, Lisa J. Stubbs
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
Adults of many species will care for young offspring that are not their own, a phenomenon called alloparenting. However, in many cases, nonparental adults must be sensitized by repeated or extended exposures to newborns before they will robustly disp
Externí odkaz:
https://doaj.org/article/1bc6bf8ff9bd4f11bfc8bdc6280e46a9
Autor:
Chih-Ying Chen, Christopher H. Seward, Yunshu Song, Manasi Inamdar, Analise M. Leddy, Huimin Zhang, Jennifer Yoo, Wei-Chun Kao, Hanna Pawlowski, Lisa J. Stubbs
Publikováno v:
Developmental Biology. 490:155-171
GALNT17 encodes a N-acetylgalactosaminyltransferase (GalNAc-T) protein specifically involved in mucin-type O-linked glycosylation of target proteins, a process important for cell adhesion, cell signaling, neurotransmitter activity, neurite outgrowth,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220fd63fc49e6d92903d31960c05eb71
https://doi.org/10.1016/j.ydbio.2022.08.002
https://doi.org/10.1016/j.ydbio.2022.08.002
Autor:
Yunshu Song, Christopher H. Seward, Chih-Ying Chen, Amber LeBlanc, Analise M. Leddy, Lisa Stubbs
Publikováno v:
bioRxiv
Rearrangements within theAUTS2region are associated with a rare syndromic disorder with intellectual disability, developmental delay and behavioral abnormalities as core features. In addition, smaller regional variants are linked to wide range of neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a220a2037b1cd2a9a4cb7898d85e6d95
https://europepmc.org/articles/PMC10187298/
https://europepmc.org/articles/PMC10187298/
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8861 (2020)
Core histone variants, such as H2A.X and H3.3, serve specialized roles in chromatin processes that depend on the genomic distributions and amino acid sequence differences of the variant proteins. Modifications of these variants alter interactions wit
Externí odkaz:
https://doaj.org/article/5621a4284d0f4985a235eb1aaee7cef6
Publikováno v:
Toxins, Vol 7, Iss 10, Pp 4099-4110 (2015)
Most pathogenic, non-O1/non-O139 serogroup Vibrio cholerae strains cause diarrheal disease in the absence of cholera toxin. Instead, many use Type 3 Secretion System (T3SS) mediated mechanisms to disrupt host cell homeostasis. We identified a T3SS ef
Externí odkaz:
https://doaj.org/article/c722d6c7eb8b479087b8e20b09d0cc6b
Autor:
Syed Abbas Bukhari, Michael C Saul, Christopher H Seward, Huimin Zhang, Miles Bensky, Noelle James, Sihai Dave Zhao, Sriram Chandrasekaran, Lisa Stubbs, Alison M Bell
Publikováno v:
PLoS Genetics, Vol 13, Iss 7, p e1006840 (2017)
Animals exhibit dramatic immediate behavioral plasticity in response to social interactions, and brief social interactions can shape the future social landscape. However, the molecular mechanisms contributing to behavioral plasticity are unclear. Her
Externí odkaz:
https://doaj.org/article/de66b683e0454c7b982deac17db72951
In many species, adults care for young offspring that are not their own, a phenomenon called alloparenting. However, most nonparental adults must be sensitized by repeated or extended exposures to newborns before they will robustly display parental-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee37fce1f01d70445783756779d378a9
https://doi.org/10.1101/2021.05.14.444198
https://doi.org/10.1101/2021.05.14.444198
Autor:
Christopher H. Seward, Hetvi Gandhi, Junmin Lee, Jia-Lin Yang, Amr A. Abdeen, Xiaochun Wang, Huimin Zhang, Kristopher A. Kilian, Thomas G. Molley, Katharina Gaus
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-9 (2020)
Communications Biology
Communications Biology
Malignant melanoma displays a high degree of cellular plasticity during disease progression. Signals in the tumor microenvironment are believed to influence melanoma plasticity through changes in the epigenetic state to guide dynamic differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99bbe1bb3dfc5bd31fa7e151a032dc5f
https://doi.org/10.1038/s42003-020-1067-1
https://doi.org/10.1038/s42003-020-1067-1