Zobrazeno 1 - 10
of 2 287
pro vyhledávání: '"H Schreiber"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The extracellular domain of tumor necrosis factor receptors (TNFR) generally require assembly into a homotrimeric quaternary structure as a prerequisite for initiation of signaling via the cytoplasmic domains. TNF receptor homotrimers are natively ac
Externí odkaz:
https://doaj.org/article/d26358ed7a8b47949f8d91edef645792
Autor:
H Schreiber
Publikováno v:
California Agriculture, Vol 11, Iss 4 (1957)
About 10% of the developed water supply in California is used for domestic or industrial purposes and 90% for crop irrigation.
Externí odkaz:
https://doaj.org/article/1a4d7b9cac294ed7afe390c08a8e0693
Publikováno v:
European Journal of Cancer. 187:147-160
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f69672ab58a4edf6e6c15eb7c483658
https://doi.org/10.1016/j.ejca.2023.03.040
https://doi.org/10.1016/j.ejca.2023.03.040
Autor:
Katherine H. Schreiber, Sebastian I. Arriola Apelo, Deyang Yu, Jacqueline A. Brinkman, Michael C. Velarde, Faizan A. Syed, Chen-Yu Liao, Emma L. Baar, Kathryn A. Carbajal, Dawn S. Sherman, Denise Ortiz, Regina Brunauer, Shany E. Yang, Stelios T. Tzannis, Brian K. Kennedy, Dudley W. Lamming
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Rapamycin extends lifespan in model organisms by targeting mTORC1, but exerts off-target side effects via inhibition of mTORC2. Here, the authors report the identification of a selective mTORC1 inhibitor, and show that it inhibits mTORC1 activity bot
Externí odkaz:
https://doaj.org/article/62fe1b728b0148059e306c8857df6c69
Autor:
George Fromm, Suresh de Silva, Kellsey Johannes, Arpita Patel, Josiah C. Hornblower, Taylor H. Schreiber
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-16 (2018)
Abstract Simultaneous blockade of immune checkpoint molecules and co-stimulation of the TNF receptor superfamily (TNFRSF) is predicted to improve overall survival in human cancer. TNFRSF co-stimulation depends upon coordinated antigen recognition thr
Externí odkaz:
https://doaj.org/article/00ca4c02959e4603a56e1722ab664fbb
Autor:
Taylor H. Schreiber, Kaiwen Huang, Kyung Jin Yoo, Arpita Patel, Kellsey Johannes, Casey W. Shuptrine, George Fromm, Suresh de Silva
Supplementary Figures 1-6 and Supplementary Tables 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209c1f14ca5731dfd580e06dd07646e7
https://doi.org/10.1158/2326-6066.22543954
https://doi.org/10.1158/2326-6066.22543954
Autor:
Taylor H. Schreiber, Kaiwen Huang, Kyung Jin Yoo, Arpita Patel, Kellsey Johannes, Casey W. Shuptrine, George Fromm, Suresh de Silva
Disrupting the binding of CD47 to SIRPα has emerged as a promising immunotherapeutic strategy for advanced cancers by potentiating antibody-dependent cellular phagocytosis (ADCP) of targeted antibodies. Preclinically, CD47/SIRPα blockade induces an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f925ce040d128dd8677e8012432388
https://doi.org/10.1158/2326-6066.c.6550477
https://doi.org/10.1158/2326-6066.c.6550477
Supplemental Figure 5 supports main Figure 5 and provides additional data on the SIINFEKL+ and FoxP3+ cells detected in the peritoneal cavity and TIL in the B16.F10-Ova model system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a284c87494c020d4c4f0eb5c880020
https://doi.org/10.1158/2326-6066.22538687
https://doi.org/10.1158/2326-6066.22538687
Supplemental Figure 2 provides the molecular characterization of all vaccine cell lines used in this manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b492a468a0aa0f6dc02194bbebc3279e
https://doi.org/10.1158/2326-6066.22538696
https://doi.org/10.1158/2326-6066.22538696
Supplemental Figure 1 provides mechanism of action schematics for gp96-Ig vaccination, T cell costimulation and lists the agonist antibodies used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68982199cf5a2c3b952a68d780bf9a45
https://doi.org/10.1158/2326-6066.22538699
https://doi.org/10.1158/2326-6066.22538699