Zobrazeno 1 - 6 of 6 pro vyhledávání: '"H S Maniar"'
1
A hierarchy of SSB protomers in replication protein A
Autor: H S Maniar, J R Mullen, C Gu, D Philipova, J Lu, S J Brill
Publikováno v: Genes & Development. 10:2222-2233
Replication Protein A (RPA) is a heterotrimeric single-stranded DNA-binding protein (SSB) found in all eukaryotic cells. RPA is known to be required for many of the same reactions catalyzed by the homotetrameric SSB of bacteria, but its origin, subun
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4229aa419a35e84bb1c1c884a8b78764
https://doi.org/10.1101/gad.10.17.2222
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2
Structural basis for chromosome X-linked agammaglobulinemia: a tyrosine kinase disease
Autor: Luigi D. Notarangelo, H S Maniar, A. D. B. Webster, Vorechovský I, Hans D. Ochs, Qili Zhu, Lennart Nilsson, David Vetrie, Janusz M. Sowadski, Mauno Vihinen
Publikováno v: Proceedings of the National Academy of Sciences. 91:12803-12807
X-linked agammaglobulinemia (XLA) is a hereditary defect of B-cell differentiation in man caused by deficiency of Bruton tyrosine kinase (BTK). A three-dimensional model for the BTK kinase domain, based on the core structure of cAMP-dependent protein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f982cd8e971b8056d3c3a1e23b1be9
https://doi.org/10.1073/pnas.91.26.12803
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3
Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down-regulated in T lymphocytes and plasma cells
Autor: C I Smith, B Baskin, P Humire-Greiff, J N Zhou, P G Olsson, H S Maniar, P Kjellén, J D Lambris, B Christensson, L Hammarström
Publikováno v: The Journal of Immunology. 152:557-565
The gene mutated in the human disease, X-linked agammaglobulinemia (XLA), is related to the Src gene family of cytoplasmic protein-tyrosine kinases and is designated Btk (Bruton's agammaglobulinemia tyrosine kinase; formerly Atk/Bpk; the human gene i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49d426aa40fdf8cd76b7508d21e0dbcd
https://doi.org/10.4049/jimmunol.152.2.557
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4
Structural basis for X-linked agammaglobulinemia (XLA): mutations at interacting Btk residues R562, W563, and A582
Autor: Mauno Vihinen, A. D. B. Webster, Lennart Nilsson, C. I. E. Smith, H S Maniar
Publikováno v: Karolinska Institutet
It has been suggested that tryptophan 563 is sandwiched between residues R562 and A582 in Bruton's agammaglobulinemia tyrosine kinase (Btk). Mutations of the surrounding residues have been shown to cause X-linked agammaglobulinemia. Substitutions R56
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec54c2c53370bf58a42691d6601e665c
https://pubmed.ncbi.nlm.nih.gov/7554468
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5
Radioprotection of euoxic bacteria by phenothiazine drugs
Autor: H. S. Maniar, B. B. Singh, C. K. K. Nair
Publikováno v: Radiation and environmental biophysics. 23(4)
Survival studies on irradiated euoxic E. coli B/r cells in presence of various concentrations of four radioprotecting phenothiazine drugs have been carried out. Maximum radioprotection was obtained at a optimal concentration for each drug and it decr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b79c9c1b832778478d9f56cc27bc8bf
https://pubmed.ncbi.nlm.nih.gov/6387773
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