A hierarchy of SSB protomers in replication protein A

Autor: H S Maniar, J R Mullen, C Gu, D Philipova, J Lu, S J Brill

Publikováno v: Genes & Development. 10:2222-2233

Replication Protein A (RPA) is a heterotrimeric single-stranded DNA-binding protein (SSB) found in all eukaryotic cells. RPA is known to be required for many of the same reactions catalyzed by the homotetrameric SSB of bacteria, but its origin, subun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4229aa419a35e84bb1c1c884a8b78764
https://doi.org/10.1101/gad.10.17.2222

Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down-regulated in T lymphocytes and plasma cells

Autor: C I Smith, B Baskin, P Humire-Greiff, J N Zhou, P G Olsson, H S Maniar, P Kjellén, J D Lambris, B Christensson, L Hammarström

Publikováno v: The Journal of Immunology. 152:557-565

The gene mutated in the human disease, X-linked agammaglobulinemia (XLA), is related to the Src gene family of cytoplasmic protein-tyrosine kinases and is designated Btk (Bruton's agammaglobulinemia tyrosine kinase; formerly Atk/Bpk; the human gene i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49d426aa40fdf8cd76b7508d21e0dbcd
https://doi.org/10.4049/jimmunol.152.2.557

Radioprotection of euoxic bacteria by phenothiazine drugs

Autor: H. S. Maniar, B. B. Singh, C. K. K. Nair

Publikováno v: Radiation and environmental biophysics. 23(4)

Survival studies on irradiated euoxic E. coli B/r cells in presence of various concentrations of four radioprotecting phenothiazine drugs have been carried out. Maximum radioprotection was obtained at a optimal concentration for each drug and it decr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b79c9c1b832778478d9f56cc27bc8bf
https://pubmed.ncbi.nlm.nih.gov/6387773

Clinical Validation of Non-invasive Simulation-Based Determination of Vascular Impedance, Wave Intensity, and Hydraulic Work in Patients Undergoing Transcatheter Aortic Valve Replacement.

Autor: Brown JY; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 77 Massachusetts Ave Building E25-RM442, Cambridge, MA, USA. brownjy@mit.edu.; Clinical and Translation Science Institute, Tufts University, Boston, MA, USA. brownjy@mit.edu.; Tufts Medical Center, Boston, MA, USA. brownjy@mit.edu., Fernandez GV; Cardiology Division, Hospital Universitario Marques de Valdecilla, IDIVAL, Santander, Spain., De La Torre Hernández JM; Cardiology Division, Hospital Universitario Marques de Valdecilla, IDIVAL, Santander, Spain., Murphy M; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 77 Massachusetts Ave Building E25-RM442, Cambridge, MA, USA., Wessler BS; Clinical and Translation Science Institute, Tufts University, Boston, MA, USA.; Tufts Medical Center, Boston, MA, USA., Edelman ER; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 77 Massachusetts Ave Building E25-RM442, Cambridge, MA, USA.; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.

Publikováno v: Annals of biomedical engineering [Ann Biomed Eng] 2024 Nov 19. Date of Electronic Publication: 2024 Nov 19.

Design and Synthesis of Novel 3‐(2‐Aminopyridin‐3‐yl)‐1,2,4‐Triazolo[4,3‐b]Pyridazine Derivatives as a Reversible Bruton's Tyrosine Kinase Inhibitors.

Autor: Park, Chi Hoon^1,2 chpark@krict.re.kr, Kim, Dukwoon³, Jung, Hyeonseok³, Jeon, Jeong Hee¹, Achary, Raghavendra¹, Lee, Joo‐Youn⁴, Kim, Pilho^1,2, Jung, Heejung¹, Hwang, Jong Yeon^1,2, Ryu, Do Hyun³, Du Ha, Jae¹, Cho, Sung Yun¹ sycho@krict.re.kr

Publikováno v: Bulletin of the Korean Chemical Society. Jul2018, Vol. 39 Issue 7, p853-857. 5p.