Výsledky vyhledávání - "H S, Boswell"

Steel factor induces serine phosphorylation of Stat3 in human growth factor-dependent myeloid cell lines

Autor: A, Gotoh, H, Takahira, C, Mantel, S, Litz-Jackson, H S, Boswell, H E, Broxmeyer

Publikováno v: Blood. 88(1)

Steel factor (SLF) acts synergistically with various hematopoietic growth factors that use the Jak-Stat pathways in vivo and in vitro, although the contribution by SLF to this pathway is unknown. We show here that SLF induces time- and dose-dependent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::57f8860bb9deed763f4279775e454ea2
https://pubmed.ncbi.nlm.nih.gov/8704168

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Adeno-associated virus 2-mediated gene transfer and functional expression of the human granulocyte-macrophage colony-stimulating factor

Autor: F, Luo, S Z, Zhou, S, Cooper, N C, Munshi, H S, Boswell, H E, Broxmeyer, A, Srivastava

Publikováno v: Experimental hematology. 23(12)

It is becoming increasingly clear that the adeno-associated virus 2 (AAV)-based vector system may prove to be useful for high-efficiency gene transfer in human cells as well as for potential gene therapy in humans. A recombinant AAV vector containing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e29ae2a33f39916b715d273a4c91782f
https://pubmed.ncbi.nlm.nih.gov/7589280

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Tyrosine phosphorylation and activation of focal adhesion kinase (p125FAK) by BCR-ABL oncoprotein

Autor: A, Gotoh, K, Miyazawa, K, Ohyashiki, T, Tauchi, H S, Boswell, H E, Broxmeyer, K, Toyama

Publikováno v: Experimental hematology. 23(11)

Focal adhesion kinase (p125FAK; FAK) is a protein tyrosine kinase that is tyrosine-phosphorylated in response to v-src-mediated transformation, cell adhesion, and stimulation with neuropeptides. To elucidate a possible functional relationship between

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::48441ade46b68edf428550f98ad97ad7
https://pubmed.ncbi.nlm.nih.gov/7556524

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Role for E2F1 in p210 BCR-ABL downstream regulation of c-myc transcription initiation. Studies in murine myeloid cells

Autor: M J, Stewart, S, Litz-Jackson, G S, Burgess, E A, Williamson, D S, Leibowitz, H S, Boswell

Publikováno v: Leukemia. 9(9)

Experiments were performed to elucidate the mechanism through which p210 BCR-ABL, by its downstream signals, regulates c-myc messenger RNA expression in hematopoietic cells. We studied a model system in which stable expression of p210 BCR-ABL in inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::327ba907549bb43403e6fdf4647c9085
https://pubmed.ncbi.nlm.nih.gov/7658719

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Granulocyte-macrophage colony-stimulating factor expression is regulated at transcriptional and posttranscriptional levels in a murine bone marrow stromal cell line

Autor: H G, Derigs, A, Reifel-Miller, K, Kaushansky, R A, Hromas, H S, Boswell

Publikováno v: Experimental hematology. 22(9)

We have reported modulation, by cytokines interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) and by hormonal cyclic-adenosine-monophosphate (cAMP) agonists, of hematopoietic growth factor production in the murine marrow adhere

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::897cdaa7fb444167ae4a9d77c70c5699
https://pubmed.ncbi.nlm.nih.gov/8062890

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p210 bcr-abl confers overexpression of inosine monophosphate dehydrogenase: an intrinsic pathway to drug resistance mediated by oncogene

Autor: K, Gharehbaghi, G S, Burgess, F R, Collart, S, Litz-Jackson, E, Huberman, H N, Jayaram, H S, Boswell

Publikováno v: Leukemia. 8(8)

The p210 bcr-abl fusion protein tyrosine kinase oncogene has been implicated in the pathogenesis of chronic granulocytic leukemia (CGL). Specific intracellular functions performed by p210 bcr-abl have recently been delineated. We considered the possi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9dfc79eff0cce65c33f8e4965c13f1b1
https://pubmed.ncbi.nlm.nih.gov/7520100

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Regulation of interleukin-1 and tumor necrosis factor-alpha induced granulocyte-macrophage colony-stimulating factor gene expression: potential involvement of arachidonic acid metabolism

Autor: M T, Rizzo, H S, Boswell

Publikováno v: Experimental hematology. 22(1)

Signal transduction pathways evoked by interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) to stimulate expression of other cytokines in mesenchymal cells are not clearly understood. Stimulation of the murine bone marrow stromal cell lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ed6282ac734bb453cab53e2a2fe4443d
https://pubmed.ncbi.nlm.nih.gov/8282065

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LIF mRNA expression is transcriptionally regulated in murine bone marrow stromal cells

Autor: H G, Derigs, H S, Boswell

Publikováno v: Leukemia. 7(4)

Recent evidence has established an important role for leukemia inhibitory factor (LIF) as hematopoietically active cytokine. The present study utilized two different murine bone marrow stromal cell lines, +/+-1.LDA11 and MBA-13, to define regulatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e6d66cc6ee0dced79519aeb4f424b0f
https://pubmed.ncbi.nlm.nih.gov/8464240

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