Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain.

Autor: J Raphael Gibbs, Marcel P van der Brug, Dena G Hernandez, Bryan J Traynor, Michael A Nalls, Shiao-Lin Lai, Sampath Arepalli, Allissa Dillman, Ian P Rafferty, Juan Troncoso, Robert Johnson, H Ronald Zielke, Luigi Ferrucci, Dan L Longo, Mark R Cookson, Andrew B Singleton

Publikováno v: PLoS Genetics, Vol 6, Iss 5, p e1000952 (2010)

A fundamental challenge in the post-genome era is to understand and annotate the consequences of genetic variation, particularly within the context of human tissues. We present a set of integrated experiments that investigate the effects of common ge

Externí odkaz: https://doaj.org/article/2c6bddb840f5434bb40322ece5b8e839

Glutamine

Autor: J. Tyson Tildon, H. Ronald Zielke

Publikováno v: Glutamine and Glutamate in Mammals ISBN: 9781351072298

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1a3b4264d573ddfb2944d1c4ceaf2f8
https://doi.org/10.1201/9781351072298-12

Novel genetic loci underlying human intracranial volume identified through genome-wide association

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Nalls, Diana Tordesillas-Gutiérrez, Martine Hoogman, Lars T. Westlye, Loes M. Olde Loohuis, Andrew Singleton, Gabriel Cuellar-Partida, Randy L. Buckner, Dorret I. Boomsma, Dena G. Hernandez, Steven G. Potkin, Sudha Seshadri, Bertram Müller-Myhsok, D. Hoehn, Gareth E. Davies, Chantal Depondt, Henrik Walter, Michael E. Weale, Deborah Janowitz, Susanne Erk, Iryna O. Fedko, Daniel R. Weinberger, Nic J A van der Wee, Jean-Luc Martinot, Jessica A. Turner, Marieke Klein, Sandra Barral, Sebastian Mohnke, Albert Hofman, Ingrid Melle, Saud Alhusaini, Vincent Chouraki, Stephen M. Lawrie, Mark E. Bastin, Juan C. Troncoso, Jean Shin, Wiro J. Niessen, Diane M. Becker, Laura Almasy, Anders M. Dale, Benjamin S. Aribisala, Dennis van 't Ent, Marco P. Boks, M. Mallar Chakravarty, Paul M. Thompson, David Reese McKay, Michael Griswold, John Blangero, Narelle K. Hansell, Eco J. C. de Geus, Paul A. Nyquist, Susana Muñoz Maniega, Sampath Arepalli, Tatjana Rundek, Dan L. Longo, Anton J. M. de Craen, Rebekah McWhirter, Nazanin Mirza-Schreiber, Henning Tiemeier, Girma Woldehawariat, Sven Cichon, Irene Pappa, Amelia A. Assareh, Sudheer Giddaluru, Pieter J. Hoekstra, Hieab H.H. Adams, Hilleke E. Hulshoff Pol, Grant W. Montgomery, Roel A. Ophoff, Markus M. Nöthen, Sara Pudas, Sigurdur Sigurdsson, Arthur W. Toga, Tien Yin Wong, Massimo Pandolfo, Corina U. Greven, Esther Walton, Tianye Jia, David J. Stott, Gunter Schumann, Marie-José van Tol, Dalia Kasperaviciute, Thomas Wolfers, Henry Völzke, Ian Ford, Shannon L. Risacher, Jessika E. Sussmann, Nicholas G. Martin, Wei Wen, Daniah Trabzuni, Iwona Kłoszewska, Kwangsik Nho, Gianpiero L. Cavalleri, Adam M. Brickman, Sungeun Kim, Andreas Heinz, Ralph L. Sacco, Neda Jahanshad, Velandai Srikanth, Elena Shumskaya, Susan H. Blanton, Katharina Wittfeld, Badri N. Vardarajan, Joshua C. Bis, Joanne E. Curran, Helena Schmidt, Peter T. Fox, Clifford R. Jack, Jason L. Stein, Laura M. E. Blanken, Thomas Espeseth, Dick J. Veltman, Sebastian Guelfi, Margaret J. Wright, Norman Delanty, Michael Czisch, Martina Papmeyer, Oscar L. Lopez, Marjolein M. J. Van Donkelaar, Bruce M. Psaty, Jan K. Buitelaar, Sven J. van der Lee, David A. Bennett, Beng-Choon Ho, Oliver Martinez, Wiepke Cahn, Li Shen, J. Wouter Jukema, Janita Bralten, Peter Kochunov, Greig I. Zubicaray, Marcel P. van der Brug, Ching-Yu Cheng, Philipp G. Sämann, Stella Trompet, Roberto Roiz-Santiañez, David C. Glahn, Allissa Dillman, Venkata S. Mattay, Dara M. Cannon, Michael W. Weiner, Christopher D. Whelan, Alexander Teumer, Sylvane Desrivières, Ole A. Andreassen, Thomas E. Nichols, Manuel Mattheisen, Matthias Nauck, René S. Kahn, Albert V. Smith, Colin Smith, Vilmundur Gudnason, Denis A. Evans, Anouk den Braber, Katie L. McMahon, Han G. Brunner, Florian Holsboer, Yuri Milaneschi, Andrew J. Saykin, Jiemin Liao, Vince D. Calhoun, Neelum T. Aggarwal, Dennis van der Meer, Hans J. Grabe, Anita L. DeStefano, Claudia L. Satizabal, Alan B. Zonderman, Alex P. Zijdenbos, Tulio Guadalupe, Ingrid Agartz, Jordan W. Smoller, Allison C. Nugent, Alejandro Arias-Vasquez, Masashi Ikeda, Avram J. Holmes, Brenda W.J.H. Penninx, John Hardy, Herve Lemaitre, Charles DeCarli, Patrizia Mecocci, Catharina A. Hartman, Tomas Axelsson, Oliver Grimm, Irina Filippi, Wayne C. Drevets, Hans van Bokhoven, Miguel E. Rentería, Aiden Corvin, Ryota Kanai, Kristel R. van Eijk, Andrew M. McIntosh, Jouke-Jan Hottenga, Roberto Toro, Lavinia Athanasiu, Joanna M. Wardlaw, Thomas H. Mosley, Mina Ryten, Meike W. Vernooij, Michelle Luciano, Joshua L. Roffman, Rebecca F. Gottesman, Dhananjay Vaidya, Ryota Hashimoto, Mar Matarin, Adaikalavan Ramasamy, Jerome I. Rotter, Ryan L. Muetzel, Konstantinos Arfanakis, Theo G.M. van Erp, Ganesh Chauhan, Xinmin Liu, Tomáš Paus, Emma Sprooten, Christiane Wolf, David S. Knopman, Manon Bernard, Zdenka Pausova, Bryan J. Traynor, Maria C. Valdés Hernández, Robert C. Green, Russell Thomson, Ravi Duggirala, Lisa R. Yanek, Luigi Ferrucci, Bing Xu, Thomas D. Dyer, Thomas H. Wassink, Eric Westman, Jennifer S. Richards, Phil H. Lee, Benno Pütz, Mark R. Cookson, Benedicto Crespo-Facorro, Natalie A. Royle, Bernd Kraemer, Katrin Hegenscheid, Francis J. McMahon, Tatiana Foroud, M. Kamran Ikram, Myriam Fornage, Nanda Rommelse, Saima Hilal, Perminder S. Sachdev, Qiang Chen, Najaf Amin, Lenore J. Launer, Norbert Hosten, Guillén Fernández, Simone Reppermund, Ashley Beecham, Dirk J. Heslenfeld, Masaki Fukunaga, Cornelia M. van Duijn, Clinton B. Wright, Erik G. Jönsson, Sanjay M. Sisodiya, Oliver Gruber, Christophe Tzourio, André G. Uitterlinden, Robert Johnson, Jaap Oosterlaan, Bernard Mazoyer, H. Ronald Zielke, Stephanie Le Hellard, Jingyun Yang, Georg Homuth, Stéphanie Debette, Nicola J. Armstrong, Sarah E. Medland, Henry Brodaty, Beverly G Windham, Gary Donohoe, Rachel M. Brouwer, James T. Becker, Kumar B. Rajan, Daan van Rooij, Thomas W. Mühleisen, Kazutaka Ohi, Peter R. Schofield, Tonya White, Barbara Franke, Unn K. Haukvik, Debra A. Fleischman, J. Raphael Gibbs, Colm McDonald, Anbupalam Thalamuthu

Publikováno v: Nature Neuroscience, 19(12), 1569. Nature Publishing Group
Adams, H H H, Hibar, D P, Chouraki, V, Stein, J L, Nyquist, P A, Rentería, M E, Trompet, S, Arias-vasquez, A, Seshadri, S, Desrivières, S, Beecham, A H, Jahanshad, N, Wittfeld, K, Van Der Lee, S J, Abramovic, L, Alhusaini, S, Amin, N, Andersson, M, Arfanakis, K, Aribisala, B S, Armstrong, N J, Athanasiu, L, Axelsson, T, Beiser, A, Bernard, M, Bis, J C, Blanken, L M E, Blanton, S H, Bohlken, M M, Boks, M P, Bralten, J, Brickman, A M, Carmichael, O, Chakravarty, M M, Chauhan, G, Chen, Q, Ching, C R K, Cuellar-partida, G, Braber, A D, Doan, N T, Ehrlich, S, Filippi, I, Ge, T, Giddaluru, S, Goldman, A L, Gottesman, R F, Greven, C U, Grimm, O, Griswold, M E, Guadalupe, T, Hass, J, Haukvik, U K, Hilal, S, Hofer, E, Hoehn, D, Holmes, A J, Hoogman, M, Janowitz, D, Jia, T, Kasperaviciute, D, Kim, S, Klein, M, Kraemer, B, Lee, P H, Liao, J, Liewald, D C M, Lopez, L M, Luciano, M, Macare, C, Marquand, A, Matarin, M, Mather, K A, Mattheisen, M, Mazoyer, B, Mckay, D R, Mcwhirter, R, Milaneschi, Y, Mirza-schreiber, N, Muetzel, R L, Maniega, S M, Nho, K, Nugent, A C, Loohuis, L M O, Oosterlaan, J, Papmeyer, M, Pappa, I, Pirpamer, L, Pudas, S, Pütz, B, Rajan, K B, Ramasamy, A, Richards, J S, Risacher, S L, Roiz-santiañez, R, Rommelse, N, Rose, E J, Royle, N A, Rundek, T, Sämann, P G, Satizabal, C L, Schmaal, L, Schork, A J, Shen, L, Shin, J, Shumskaya, E, Smith, A V, Sprooten, E, Strike, L T, Teumer, A, Thomson, R, Tordesillas-gutierrez, D, Toro, R, Trabzuni, D, Vaidya, D, Van Der Grond, J, Van Der Meer, D, Van Donkelaar, M M J, Van Eijk, K R, Van Erp, T G M, Van Rooij, D, Walton, E, Westlye, L T, Whelan, C D, Windham, B G, Winkler, A M, Woldehawariat, G, Wolf, C, Wolfers, T, Xu, B, Yanek, L R, Yang, J, Zijdenbos, A, Zwiers, M P, Agartz, I, Aggarwal, N T, Almasy, L, Ames, D, Amouyel, P, Andreassen, O A, Arepalli, S, Assareh, A A, Barral, S, Bastin, M E, Becker, D M, Becker, J T, Bennett, D A, Blangero, J, Van Bokhoven, H, Boomsma, D I, Brodaty, H, Brouwer, R M, Brunner, H G, Buckner, R L, Buitelaar, J K, Bulayeva, K B, Cahn, W, Calhoun, V D, Cannon, D M, Cavalleri, G L, Chen, C, Cheng, C, Cichon, S, Cookson, M R, Corvin, A, Crespo-facorro, B, Curran, J E, Czisch, M, Dale, A M, Davies, G E, De Geus, E J C, De Jager, P L, De Zubicaray, G I, Delanty, N, Depondt, C, Destefano, A L, Dillman, A, Djurovic, S, Donohoe, G, Drevets, W C, Duggirala, R, Dyer, T D, Erk, S, Espeseth, T, Evans, D A, Fedko, I O, Fernández, G, Ferrucci, L, Fisher, S E, Fleischman, D A, Ford, I, Foroud, T M, Fox, P T, Francks, C, Fukunaga, M, Gibbs, J R, Glahn, D C, Gollub, R L, Göring, H H H, Grabe, H J, Green, R C, Gruber, O, Gudnason, V, Guelfi, S, Hansell, N K, Hardy, J, Hartman, C A, Hashimoto, R, Hegenscheid, K, Heinz, A, Le Hellard, S, Hernandez, D G, Heslenfeld, D J, Ho, B, Hoekstra, P J, Hoffmann, W, Hofman, A, Holsboer, F, Homuth, G, Hosten, N, Hottenga, J, Pol, H E H, Ikeda, M, Ikram, M K, Jack, C R, Jenkinson, M, Johnson, R, Jönsson, E G, Jukema, J W, Kahn, R S, Kanai, R, Kloszewska, I, Knopman, D S, Kochunov, P, Kwok, J B, Lawrie, S M, Lemaître, H, Liu, X, Longo, D L, Longstreth, W T, Lopez, O L, Lovestone, S, Martinez, O, Martinot, J, Mattay, V S, Mcdonald, C, Mcintosh, A M, Mcmahon, K L, Mcmahon, F J, Mecocci, P, Melle, I, Meyer-lindenberg, A, Mohnke, S, Montgomery, G W, Morris, D W, Mosley, T H, Mühleisen, T W, Müller-myhsok, B, Nalls, M A, Nauck, M, Nichols, T E, Niessen, W J, Nöthen, M M, Nyberg, L, Ohi, K, Olvera, R L, Ophoff, R A, Pandolfo, M, Paus, T, Pausova, Z, Penninx, B W J H, Pike, G B, Potkin, S G, Psaty, B M, Reppermund, S, Rietschel, M, Roffman, J L, Romanczuk-seiferth, N, Rotter, J I, Ryten, M, Sacco, R L, Sachdev, P S, Saykin, A J, Schmidt, R, Schofield, P R, Sigurdsson, S, Simmons, A, Singleton, A, Sisodiya, S M, Smith, C, Smoller, J W, Soininen, H, Srikanth, V, Steen, V M, Stott, D J, Sussmann, J E, Thalamuthu, A, Tiemeier, H, Toga, A W, Traynor, B J, Troncoso, J, Turner, J A, Tzourio, C, Uitterlinden, A G, Hernández, M C V, Van Der Brug, M, Van Der Lugt, A, Van Der Wee, N J A, Van Duijn, C M, Van Haren, N E M, Van ′t Ent, D, Van Tol, M, Vardarajan, B N, Veltman, D J, Vernooij, M W, Völzke, H, Walter, H, Wardlaw, J M, Wassink, T H, Weale, M E, Weinberger, D R, Weiner, M W, Wen, W, Westman, E, White, T, Wong, T Y, Wright, C B, Zielke, H R, Zonderman, A B, Deary, I J, Decarli, C, Schmidt, H, Martin, N G, De Craen, A J M, Wright, M J, Launer, L J, Schumann, G, Fornage, M, Franke, B, Debette, S, Medland, S E, Ikram, M A & Thompson, P M 2016, ' Novel genetic loci underlying human intracranial volume identified through genome-wide association ', Nature Neuroscience, vol. 19, no. 12, pp. 1569-1582 . https://doi.org/10.1038/nn.4398
Adams, H H H, Hibar, D P, Chouraki, V, Stein, J L, Nyquist, P A, Renteria, M E, Trompet, S, Arias Vazquez, A, Seshadri, S, Desrivieres, S, den Braber, A, Boomsma, D I, de Geus, E J C, Fedko, I O, Hottenga, J J, Hulshoff Pol, H E, Penninx, B W J H, de Craen, A J, Wright, M J, Launer, L J, Schumann, G, van t Ent, D, Fornage, M, Franke, B, Debette, S, Medland, S E, Arfan Ikram, M & Thompson, P M 2016, ' Novel genetic loci underlying human intracranial volume identified through genome-wide association ', Nature Neuroscience, vol. 19, no. 12, pp. 1569-1582 . https://doi.org/10.1038/nn.4398
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2016, 19 (12), pp.1569-1582. ⟨10.1038/nn.4398⟩
Nature Neuroscience, 19(12), 1569-1582. Nature Publishing Group
Adams, H H H, Hibar, D P, Chouraki, V, Stein, J L, Nyquist, P A, Rentería, M E, Trompet, S, Arias-Vasquez, A, Seshadri, S, Desrivières, S, Beecham, A H, Jahanshad, N, Wittfeld, K, Van der Lee, S J, Abramovic, L, Alhusaini, S, Amin, N, Andersson, M, Arfanakis, K, Aribisala, B S, Armstrong, N J, Athanasiu, L, Axelsson, T, Beiser, A, Bernard, M, Bis, J C, Blanken, L M E, Blanton, S H, Bohlken, M M, Boks, M P, Bralten, J, Brickman, A M, Carmichael, O, Chakravarty, M M, Chauhan, G, Chen, Q, Ching, C R K, Cuellar-Partida, G, Braber, A D, Doan, N T, Ehrlich, S, Filippi, I, Ge, T, Giddaluru, S, Goldman, A L, Gottesman, R F, Greven, C U, Grimm, O, Griswold, M E, Guadalupe, T, Hass, J, Haukvik, U K, Hilal, S, Hofer, E, Hoehn, D, Holmes, A J, Hoogman, M, Janowitz, D, Jia, T, Kasperaviciute, D, Kim, S, Klein, M, Kraemer, B, Lee, P H, Liao, J, Liewald, D C M, Lopez, L M, Luciano, M, Macare, C, Marquand, A, Matarin, M, Mather, K A, Mattheisen, M, Mazoyer, B, McKay, D R, McWhirter, R, Milaneschi, Y, Mirza-Schreiber, N, Muetzel, R L, Maniega, S M, Nho, K, Nugent, A C, Loohuis, L M O, Oosterlaan, J, Papmeyer, M, Pappa, I, Pirpamer, L, Pudas, S, Pütz, B, Rajan, K B, Ramasamy, A, Richards, J S, Risacher, S L, Roiz-Santiañez, R, Rommelse, N, Royle, N A, Rundek, T, Sämann, P G, Satizabal, C L, Schmaal, L, Schork, A J, Shen, L, Shin, J, Shumskaya, E, Smith, A V, Sprooten, E, Strike, L T, Teumer, A, Thomson, R, Tordesillas-Gutierrez, D, Toro, R, Trabzuni, D, Vaidya, D, Van der Grond, J, Van der Meer, D, Van Donkelaar, M M J, Van Eijk, K R, Van Erp, T G M, Van Rooij, D, Walton, E, Westlye, L T, Whelan, C D, Windham, B G, Winkler, A M, Woldehawariat, G, Wolf, C, Wolfers, T, Xu, B, Yanek, L R, Yang, J, Zijdenbos, A, Zwiers, M P, Agartz, I, Aggarwal, N T, Almasy, L, Ames, D, Amouyel, P, Andreassen, O A, Arepalli, S, Assareh, A A, Barral, S, Bastin, M E, Becker, D M, Becker, J T, Blangero, J, van Bokhoven, H, Boomsma, D I, Brodaty, H, Brouwer, R M, Brunner, H G, Buckner, R L, Buitelaar, J K, Bulayeva, K B, Cahn, W, Calhoun, V D, Cannon, D M, Cavalleri, G L, Chen, C, Cichon, S, Cookson, M R, Corvin, A, Crespo-Facorro, B, Curran, J E, Czisch, M, Dale, A M, De Geus, E J C, De Jager, P L, de Zubicaray, G I, Delanty, N, Depondt, C, DeStefano, A L, Dillman, A, Djurovic, S, Donohoe, G, Drevets, W C, Duggirala, R, Dyer, T D, Erk, S, Espeseth, T, Evans, D A, Fedko, I O, Fernández, G, Ferrucci, L, Fisher, S E, Fleischman, D A, Ford, I, Foroud, T M, Fox, P T, Francks, C, Fukunaga, M, Gibbs, J R, Glahn, D C, Gollub, R L, Göring, H H H, Grabe, H J, Gruber, O, Gudnason, V, Guelfi, S, Hansell, N K, Hartman, C A, Hashimoto, R, Hegenscheid, K, Heinz, A, Le Hellard, S, Hernandez, D G, Heslenfeld, D J, Ho, B-C, Hoekstra, P J, Hoffmann, W, Hofman, A, Holsboer, F, Homuth, G, Hosten, N, Hottenga, J-J, Pol, H E H, Ikeda, M, Ikram, M K, Jr, C R J, Jönsson, E G, Jukema, J W, Kahn, R S, Kanai, R, Kloszewska, I, Knopman, D S, Kochunov, P, Kwok, J B, Lawrie, S M, Lemaître, H, Liu, X, Longo, D L, Jr, W T L, Lopez, O L, Lovestone, S, Martinez, O, Martinot, J-L, Mattay, V S, McDonald, C, McIntosh, A M, McMahon, K L, McMahon, F J, Mecocci, P, Melle, I, Meyer-Lindenberg, A, Mohnke, S, Montgomery, G W, Morris, D W, Mosley, T H, Mühleisen, T W, Müller-Myhsok, B, Nalls, M A, Nauck, M, Nichols, T E, Niessen, W J, Nöthen, M M, Nyberg, L, Ohi, K, Olvera, R L, Ophoff, R A, Pandolfo, M, Paus, T, Penninx, B W J H, Pike, G B, Potkin, S G, Psaty, B M, Reppermund, S, Rietschel, M, Roffman, J L, Romanczuk-Seiferth, N, Rotter, J I, Ryten, M, Sacco, R L, Sachdev, P S, Saykin, A J, Schmidt, R, Schofield, P R, Sigurdsson, S, Simmons, A, Singleton, A, Sisodiya, S M, Smoller, J W, Soininen, H, Srikanth, V, Steen, V M, Stott, D J, Sussmann, J E, Thalamuthu, A, Tiemeier, H, Toga, A W, Traynor, B J, Troncoso, J, Tzourio, C, Uitterlinden, A G, Hernández, M C V, Van der Brug, M, Van der Lugt, A, Van der Wee, N J A, Van Duijn, C M, Van Haren, N E M, Van T Ent, D, Van Tol, M-J, Vardarajan, B N, Veltman, D J, Vernooij, M W, Völzke, H, Walter, H, Wardlaw, J M, Wassink, T H, Weale, M E, Weinberger, D R, Weiner, M W, Wen, W, Westman, E, White, T, Wong, T Y, Wright, C B, Zielke, H R, Zonderman, A B, Deary, I J, DeCarli, C, Schmidt, H, Martin, N G, De Craen, A J M, Wright, M J, Launer, L J, Schumann, G, Fornage, M, Franke, B, Debette, S, Ikram, M A & Thompson, P M 2016, ' Novel genetic loci underlying human intracranial volume identified through genome-wide association ', Nature Neuroscience, vol. 19, no. 12, pp. 1569-1582 . https://doi.org/10.1038/nn.4398
Nature Neuroscience, 19, 1569-1582
Adams, H H H, Hibar, D P, Chouraki, V, Stein, J L, Nyquist, P A, Rentería, M E, Trompet, S, Arias-Vasquez, A, Seshadri, S, Desrivières, S, Beecham, A H, Jahanshad, N, Wittfeld, K, Van der Lee, S J, Abramovic, L, Alhusaini, S, Amin, N, Andersson, M, Arfanakis, K, Aribisala, B S, Armstrong, N J, Athanasiu, L, Axelsson, T, Beiser, A, Bernard, M, Bis, J C, Blanken, L M E, Blanton, S H, Bohlken, M M, Boks, M P, Bralten, J, Brickman, A M, Carmichael, O, Chakravarty, M M, Chauhan, G, Chen, Q, Ching, C R K, Cuellar-Partida, G, Braber, A D, Doan, N T, Ehrlich, S, Filippi, I, Ge, T, Giddaluru, S, Goldman, A L, Gottesman, R F, Greven, C U, Grimm, O, Griswold, M E, Guadalupe, T, Hass, J, Haukvik, U K, Hilal, S, Hofer, E, Hoehn, D, Holmes, A J, Hoogman, M, Janowitz, D, Jia, T, Kasperaviciute, D, Kim, S, Klein, M, Kraemer, B, Lee, P H, Liao, J, Liewald, D C M, Lopez, L M, Luciano, M, Macare, C, Marquand, A, Matarin, M, Mather, K A, Mattheisen, M, Mazoyer, B, McKay, D R, McWhirter, R, Milaneschi, Y, Mirza-Schreiber, N, Muetzel, R L, Maniega, S M, Nho, K, Nugent, A C, Loohuis, L M O, Oosterlaan, J, Papmeyer, M, Pappa, I, Pirpamer, L, Pudas, S, Pütz, B, Rajan, K B, Ramasamy, A, Richards, J S, Risacher, S L, Roiz-Santiañez, R, Rommelse, N, Rose, E J, Royle, N A, Rundek, T, Sämann, P G, Satizabal, C L, Schmaal, L, Schork, A J, Shen, L, Shin, J, Shumskaya, E, Smith, A V, Sprooten, E, Strike, L T, Teumer, A, Thomson, R, Tordesillas-Gutierrez, D, Toro, R, Trabzuni, D, Vaidya, D, Van der Grond, J, Van der Meer, D, Van Donkelaar, M M J, Van Eijk, K R, Van Erp, T G M, Van Rooij, D, Walton, E, Westlye, L T, Whelan, C D, Windham, B G, Winkler, A M, Woldehawariat, G, Wolf, C, Wolfers, T, Xu, B, Yanek, L R, Yang, J, Zijdenbos, A, Zwiers, M P, Agartz, I, Aggarwal, N T, Almasy, L, Ames, D, Amouyel, P, Andreassen, O A, Arepalli, S, Assareh, A A, Barral, S, Bastin, M E, Becker, D M, Becker, J T, Bennett, D A, Blangero, J, van Bokhoven, H, Boomsma, D I, Brodaty, H, Brouwer, R M, Brunner, H G, Buckner, R L, Buitelaar, J K, Bulayeva, K B, Cahn, W, Calhoun, V D, Cannon, D M, Cavalleri, G L, Chen, C, Cheng, C-Y, Cichon, S, Cookson, M R, Corvin, A, Crespo-Facorro, B, Curran, J E, Czisch, M, Dale, A M, Davies, G E, De Geus, E J C, De Jager, P L, de Zubicaray, G I, Delanty, N, Depondt, C, DeStefano, A L, Dillman, A, Djurovic, S, Donohoe, G, Drevets, W C, Duggirala, R, Dyer, T D, Erk, S, Espeseth, T, Evans, D A, Fedko, I O, Fernández, G, Ferrucci, L, Fisher, S E, Fleischman, D A, Ford, I, Foroud, T M, Fox, P T, Francks, C, Fukunaga, M, Gibbs, J R, Glahn, D C, Gollub, R L, Göring, H H H, Grabe, H J, Green, R C, Gruber, O, Gudnason, V, Guelfi, S, Hansell, N K, Hardy, J, Hartman, C A, Hashimoto, R, Hegenscheid, K, Heinz, A, Le Hellard, S, Hernandez, D G, Heslenfeld, D J, Ho, B-C, Hoekstra, P J, Hoffmann, W, Hofman, A, Holsboer, F, Homuth, G, Hosten, N, Hottenga, J-J, Pol, H E H, Ikeda, M, Ikram, M K, Jack, C R, Jenkinson, M, Johnson, R, Jönsson, E G, Jukema, J W, Kahn, R S, Kanai, R, Kloszewska, I, Knopman, D S, Kochunov, P, Kwok, J B, Lawrie, S M, Lemaître, H, Liu, X, Longo, D L, Longstreth, W T, Lopez, O L, Lovestone, S, Martinez, O, Martinot, J-L, Mattay, V S, McDonald, C, McIntosh, A M, McMahon, K L, McMahon, F J, Mecocci, P, Melle, I, Meyer-Lindenberg, A, Mohnke, S, Montgomery, G W, Morris, D W, Mosley, T H, Mühleisen, T W, Müller-Myhsok, B, Nalls, M A, Nauck, M, Nichols, T E, Niessen, W J, Nöthen, M M, Nyberg, L, Ohi, K, Olvera, R L, Ophoff, R A, Pandolfo, M, Paus, T, Pausova, Z, Penninx, B W J H, Pike, G B, Potkin, S G, Psaty, B M, Reppermund, S, Rietschel, M, Roffman, J L, Romanczuk-Seiferth, N, Rotter, J I, Ryten, M, Sacco, R L, Sachdev, P S, Saykin, A J, Schmidt, R, Schofield, P R, Sigurdsson, S, Simmons, A, Singleton, A, Sisodiya, S M, Smith, C, Smoller, J W, Soininen, H, Srikanth, V, Steen, V M, Stott, D J, Sussmann, J E, Thalamuthu, A, Tiemeier, H, Toga, A W, Traynor, B J, Troncoso, J, Turner, J A, Tzourio, C, Uitterlinden, A G, Hernández, M C V, Van der Brug, M, Van der Lugt, A, Van der Wee, N J A, Van Duijn, C M, Van Haren, N E M, Van T Ent, D, Van Tol, M-J, Vardarajan, B N, Veltman, D J, Vernooij, M W, Völzke, H, Walter, H, Wardlaw, J M, Wassink, T H, Weale, M E, Weinberger, D R, Weiner, M W, Wen, W, Westman, E, White, T, Wong, T Y, Wright, C B, Zielke, H R, Zonderman, A B, Deary, I J, DeCarli, C, Schmidt, H, Martin, N G, De Craen, A J M, Wright, M J, Launer, L J, Schumann, G, Fornage, M, Franke, B, Debette, S, Medland, S E, Ikram, M A & Thompson, P M 2016, ' Novel genetic loci underlying human intracranial volume identified through genome-wide association ', Nature Neuroscience, vol. 19, no. 12, pp. 1569-1582 . https://doi.org/10.1038/nn.4398
Nat Neurosci. 2016 Dec;19(12):1569-1582
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Nature Neuroscience, 19(12), 1569-1582
Nature Neuroscience, 2016, 19 (12), pp.1569-1582. ⟨10.1038/nn.4398⟩
Adams, H H H, Hibar, D P, Chouraki, V, Stein, J L, Nyquist, P A, Rentería, M E, Trompet, S, Arias-Vasquez, A, Seshadri, S, Desrivières, S, Beecham, A H, Jahanshad, N, Wittfeld, K, Van der Lee, S J, Abramovic, L, Alhusaini, S, Amin, N, Andersson, M, Arfanakis, K, Aribisala, B S, Armstrong, N J, Athanasiu, L, Axelsson, T, Beiser, A, Bernard, M, Bis, J C, Blanken, L M E, Blanton, S H, Bohlken, M M, Boks, M P, Bralten, J, Brickman, A M, Carmichael, O, Chakravarty, M M, Chauhan, G, Chen, Q, Ching, C R K, Cuellar-Partida, G, Braber, A D, Doan, N T, Ehrlich, S, Filippi, I, Ge, T, Giddaluru, S, Goldman, A L, Gottesman, R F, Greven, C U, Grimm, O, Griswold, M E, Guadalupe, T, Hass, J, Haukvik, U K, Hilal, S, Hofer, E, Hoehn, D, Holmes, A J, Hoogman, M, Janowitz, D, Jia, T, Kasperaviciute, D, Kim, S, Klein, M, Kraemer, B, Lee, P H, Liao, J, Liewald, D C M, Lopez, L M, Luciano, M, Macare, C, Marquand, A, Matarin, M, Mather, K A, Mattheisen, M, Mazoyer, B, McKay, D R, McWhirter, R, Milaneschi, Y, Mirza-Schreiber, N, Muetzel, R L, Maniega, S M, Nho, K, Nugent, A C, Loohuis, L M O, Oosterlaan, J, Papmeyer, M, Pappa, I, Pirpamer, L, Pudas, S, Pütz, B, Rajan, K B, Ramasamy, A, Richards, J S, Risacher, S L, Roiz-Santiañez, R, Rommelse, N, Rose, E J, Royle, N A, Rundek, T, Sämann, P G, Satizabal, C L, Schmaal, L, Schork, A J, Shen, L, Shin, J, Shumskaya, E, Smith, A V, Sprooten, E, Strike, L T, Teumer, A, Thomson, R, Tordesillas-Gutierrez, D, Toro, R, Trabzuni, D, Vaidya, D, Van der Grond, J, Van der Meer, D, Van Donkelaar, M M J, Van Eijk, K R, Van Erp, T G M, Van Rooij, D, Walton, E, Westlye, L T, Whelan, C D, Windham, B G, Winkler, A M, Woldehawariat, G, Wolf, C, Wolfers, T, Xu, B, Yanek, L R, Yang, J, Zijdenbos, A, Zwiers, M P, Agartz, I, Aggarwal, N T, Almasy, L, Ames, D, Amouyel, P, Andreassen, O A, Arepalli, S, Assareh, A A, Barral, S, Bastin, M E, Becker, D M, Becker, J T, Bennett, D A, Blangero, J, van Bokhoven, H, Boomsma, D I, Brodaty, H, Brouwer, R M, Brunner, H G, Buckner, R L, Buitelaar, J K, Bulayeva, K B, Cahn, W, Calhoun, V D, Cannon, D M, Cavalleri, G L, Chen, C, Cheng, C-Y, Cichon, S, Cookson, M R, Corvin, A, Crespo-Facorro, B, Curran, J E, Czisch, M, Dale, A M, Davies, G E, De Geus, E J C, De Jager, P L, de Zubicaray, G I, Delanty, N, Depondt, C, DeStefano, A L, Dillman, A, Djurovic, S, Donohoe, G, Drevets, W C, Duggirala, R, Dyer, T D, Erk, S, Espeseth, T, Evans, D A, Fedko, I O, Fernández, G, Ferrucci, L, Fisher, S E, Fleischman, D A, Ford, I, Foroud, T M, Fox, P T, Francks, C, Fukunaga, M, Gibbs, J R, Glahn, D C, Gollub, R L, Göring, H H H, Grabe, H J, Green, R C, Gruber, O, Gudnason, V, Guelfi, S, Hansell, N K, Hardy, J, Hartman, C A, Hashimoto, R, Hegenscheid, K, Heinz, A, Le Hellard, S, Hernandez, D G, Heslenfeld, D J, Ho, B-C, Hoekstra, P J, Hoffmann, W, Hofman, A, Holsboer, F, Homuth, G, Hosten, N, Hottenga, J-J, Pol, H E H, Ikeda, M, Ikram, M K, Jr, C R J, Jenkinson, M, Johnson, R, Jönsson, E G, Jukema, J W, Kahn, R S, Kanai, R, Kloszewska, I, Knopman, D S, Kochunov, P, Kwok, J B, Lawrie, S M, Lemaître, H, Liu, X, Longo, D L, Jr, W T L, Lopez, O L, Lovestone, S, Martinez, O, Martinot, J-L, Mattay, V S, McDonald, C, McIntosh, A M, McMahon, K L, McMahon, F J, Mecocci, P, Melle, I, Meyer-Lindenberg, A, Mohnke, S, Montgomery, G W, Morris, D W, Mosley, T H, Mühleisen, T W, Müller-Myhsok, B, Nalls, M A, Nauck, M, Nichols, T E, Niessen, W J, Nöthen, M M, Nyberg, L, Ohi, K, Olvera, R L, Ophoff, R A, Pandolfo, M, Paus, T, Pausova, Z, Penninx, B W J H, Pike, G B, Potkin, S G, Psaty, B M, Reppermund, S, Rietschel, M, Roffman, J L, Romanczuk-Seiferth, N, Rotter, J I, Ryten, M, Sacco, R L, Sachdev, P S, Saykin, A J, Schmidt, R, Schofield, P R, Sigurdsson, S, Simmons, A, Singleton, A, Sisodiya, S M, Smith, C, Smoller, J W, Soininen, H, Srikanth, V, Steen, V M, Stott, D J, Sussmann, J E, Thalamuthu, A, Tiemeier, H, Toga, A W, Traynor, B J, Troncoso, J, Turner, J A, Tzourio, C, Uitterlinden, A G, Hernández, M C V, Van der Brug, M, Van der Lugt, A, Van der Wee, N J A, Van Duijn, C M, Van Haren, N E M, Van 't Ent, D, Van Tol, M-J, Vardarajan, B N, Veltman, D J, Vernooij, M W, Völzke, H, Walter, H, Wardlaw, J M, Wassink, T H, Weale, M E, Weinberger, D R, Weiner, M W, Wen, W, Westman, E, White, T, Wong, T Y, Wright, C B, Zielke, H R, Zonderman, A B, Deary, I J, DeCarli, C, Schmidt, H, Martin, N G, De Craen, A J M, Wright, M J, Launer, L J, Schumann, G, Fornage, M, Franke, B, Debette, S, Medland, S E, Ikram, M A & Thompson, P M 2016, ' Novel genetic loci underlying human intracranial volume identified through genome-wide association ', Nature Neuroscience, vol. 19, no. 12, pp. 1569–1582 . https://doi.org/10.1038/nn.4398
Nature neuroscience, 19(12), 1569-1582. NATURE AMERICA INC
Nature reviews / Neuroscience 19(12), 1569-1582 (2016). doi:10.1038/nn.4398
Adams, H H H, Hibar, D P, Chouraki, V, Stein, J L, Nyquist, P A, Rentería, M E, Trompet, S, Arias-Vasquez, A, Seshadri, S, Desrivières, S, Beecham, A H, Jahanshad, N, Wittfeld, K, Van der Lee, S J, Abramovic, L, Alhusaini, S, Amin, N, Andersson, M, Arfanakis, K, Aribisala, B S, Armstrong, N J, Athanasiu, L, Axelsson, T, Beiser, A, Bernard, M, Bis, J C, Blanken, L M E, Blanton, S H, Bohlken, M M, Boks, M P, Bralten, J, Brickman, A M, Carmichael, O, Chakravarty, M M, Chauhan, G, Chen, Q, Ching, C R K, Cuellar-Partida, G, Braber, A D, Doan, N T, Ehrlich, S, Filippi, I, Ge, T, Giddaluru, S, Goldman, A L, Gottesman, R F, Greven, C U, Grimm, O, Griswold, M E, Guadalupe, T, Hass, J, Haukvik, U K, Hilal, S, Hofer, E, Hoehn, D, Holmes, A J, Hoogman, M, Janowitz, D, Jia, T, Kasperaviciute, D, Kim, S, Klein, M, Kraemer, B, Lee, P H, Liao, J, Liewald, D C M, Lopez, L M, Luciano, M, Macare, C, Marquand, A, Matarin, M, Mather, K A, Mattheisen, M, Mazoyer, B, McKay, D R, McWhirter, R, Milaneschi, Y, Mirza-Schreiber, N, Muetzel, R L, Maniega, S M, Nho, K, Nugent, A C, Loohuis, L M O, Oosterlaan, J, Papmeyer, M, Pappa, I, Pirpamer, L, Pudas, S, Pütz, B, Rajan, K B, Ramasamy, A, Richards, J S, Risacher, S L, Roiz-Santiañez, R, Rommelse, N, Rose, E J, Royle, N A, Rundek, T, Sämann, P G, Satizabal, C L, Schmaal, L, Schork, A J, Shen, L, Shin, J, Shumskaya, E, Smith, A V, Sprooten, E, Strike, L T, Teumer, A, Thomson, R, Tordesillas-Gutierrez, D, Toro, R, Trabzuni, D, Vaidya, D, Van der Grond, J, Van der Meer, D, Van Donkelaar, M M J, Van Eijk, K R, Van Erp, T G M, Van Rooij, D, Walton, E, Westlye, L T, Whelan, C D, Windham, B G, Winkler, A M, Woldehawariat, G, Wolf, C, Wolfers, T, Xu, B, Yanek, L R, Yang, J, Zijdenbos, A, Zwiers, M P, Agartz, I, Aggarwal, N T, Almasy, L, Ames, D, Amouyel, P, Andreassen, O A, Arepalli, S, Assareh, A A, Barral, S, Bastin, M E, Becker, D M, Becker, J T, Bennett, D A, Blangero, J, van Bokhoven, H, Boomsma, D I, Brodaty, H, Brouwer, R M, Brunner, H G, Buckner, R L, Buitelaar, J K, Bulayeva, K B, Cahn, W, Calhoun, V D, Cannon, D M, Cavalleri, G L, Chen, C, Cheng, C-Y, Cichon, S, Cookson, M R, Corvin, A, Crespo-Facorro, B, Curran, J E, Czisch, M, Dale, A M, Davies, G E, De Geus, E J C, De Jager, P L, de Zubicaray, G I, Delanty, N, Depondt, C, DeStefano, A L, Dillman, A, Djurovic, S, Donohoe, G, Drevets, W C, Duggirala, R, Dyer, T D, Erk, S, Espeseth, T, Evans, D A, Fedko, I O, Fernández, G, Ferrucci, L, Fisher, S E, Fleischman, D A, Ford, I, Foroud, T M, Fox, P T, Francks, C, Fukunaga, M, Gibbs, J R, Glahn, D C, Gollub, R L, Göring, H H H, Grabe, H J, Green, R C, Gruber, O, Gudnason, V, Guelfi, S, Hansell, N K, Hardy, J, Hartman, C A, Hashimoto, R, Hegenscheid, K, Heinz, A, Le Hellard, S, Hernandez, D G, Heslenfeld, D J, Ho, B-C, Hoekstra, P J, Hoffmann, W, Hofman, A, Holsboer, F, Homuth, G, Hosten, N, Hottenga, J-J, Pol, H E H, Ikeda, M, Ikram, M K, Jr, C R J, Jenkinson, M, Johnson, R, Jönsson, E G, Jukema, J W, Kahn, R S, Kanai, R, Kloszewska, I, Knopman, D S, Kochunov, P, Kwok, J B, Lawrie, S M, Lemaître, H, Liu, X, Longo, D L, Jr, W T L, Lopez, O L, Lovestone, S, Martinez, O, Martinot, J-L, Mattay, V S, McDonald, C, McIntosh, A M, McMahon, K L, McMahon, F J, Mecocci, P, Melle, I, Meyer-Lindenberg, A, Mohnke, S, Montgomery, G W, Morris, D W, Mosley, T H, Mühleisen, T W, Müller-Myhsok, B, Nalls, M A, Nauck, M, Nichols, T E, Niessen, W J, Nöthen, M M, Nyberg, L, Ohi, K, Olvera, R L, Ophoff, R A, Pandolfo, M, Paus, T, Pausova, Z, Penninx, B W J H, Pike, G B, Potkin, S G, Psaty, B M, Reppermund, S, Rietschel, M, Roffman, J L, Romanczuk-Seiferth, N, Rotter, J I, Ryten, M, Sacco, R L, Sachdev, P S, Saykin, A J, Schmidt, R, Schofield, P R, Sigurdsson, S, Simmons, A, Singleton, A, Sisodiya, S M, Smith, C, Smoller, J W, Soininen, H, Srikanth, V, Steen, V M, Stott, D J, Sussmann, J E, Thalamuthu, A, Tiemeier, H, Toga, A W, Traynor, B J, Troncoso, J, Turner, J A, Tzourio, C, Uitterlinden, A G, Hernández, M C V, Van der Brug, M, Van der Lugt, A, Van der Wee, N J A, Van Duijn, C M, Van Haren, N E M, Van T Ent, D, Van Tol, M-J, Vardarajan, B N, Veltman, D J, Vernooij, M W, Völzke, H, Walter, H, Wardlaw, J M, Wassink, T H, Weale, M E, Weinberger, D R, Weiner, M W, Wen, W, Westman, E, White, T, Wong, T Y, Wright, C B, Zielke, H R, Zonderman, A B, Deary, I J, DeCarli, C, Schmidt, H, Martin, N G, De Craen, A J M, Wright, M J, Launer, L J, Schumann, G, Fornage, M, Franke, B, Debette, S, Medland, S E, Ikram, M A & Thompson, P M 2016, ' Novel genetic loci underlying human intracranial volume identified through genome-wide association ', Nature Neuroscience, vol. 19, pp. 1569-1582 . https://doi.org/10.1038/nn.4398
Nature Neuroscience, 19, 12, pp. 1569-1582

Contains fulltext : 165723pub.pdf (Publisher’s version ) (Closed access) Intracranial volume reflects the maximally attained brain size during development, and remains stable with loss of tissue in late life. It is highly heritable, but the underly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b774374601f8df488a957fcf8119e478
https://dspace.library.uu.nl/handle/1874/343369

An anatomically comprehensive atlas of the adult human brain transcriptome

Autor: Susan M. Sunkin, Preston M. Cartagena, Robert Howard, Christian F. Beckmann, David Feng, Zeb Haradon, Chinh Dang, Angela L. Guillozet-Bongaarts, Derric Williams, Jeff Goldy, Yang Li, Rachel A. Dalley, Tracy Lemon, Darren Bertagnolli, Clifford R. Slaughterbeck, Simon Smith, Steve Horvath, Christof Koch, Amanda Ebbert, Andreas Jeromin, Paul Wohnoutka, Michael Hawrylycz, Andy J. Sodt, Beryl Swanson, H. Ronald Zielke, Zackery L. Riley, John A. Morris, Evan T. Lazarz, Chris Abajian, Allan R. Jones, Mike Chapin, Changkyu Lee, Pedro Adolfo Sequeira, Jay Schulkin, Christopher Lau, Jeremy A. Miller, Tim A. Dolbeare, Ling Li, Nick Dee, Sheana Parry, Barry Daly, Patrick D. Parker, Marty Kinnunen, Amy Bernard, Joshua J. Royall, Vance Faber, John G. Hohmann, Patrick R. Hof, Stephen M. Smith, Suvro Datta, Kimberly A. Smith, Elaine H. Shen, Caroline C. Overly, Ed S. Lein, Jayson M. Jochim, Benjamin W. Gregor, Melissa Reding, M. Mallar Chakravarty, Seth G. N. Grant, Lydia Ng, Jimmy Chong, Marquis P. Vawter, Daniel H. Geschwind, David R. Haynor, Andrew F. Boe, Louie N. van de Lagemaat, David R. Fowler

Publikováno v: Nature, 489(7416), 391-399. Nature Publishing Group
Nature; Vol 489
Nature

Neuroanatomically precise, genome-wide maps of transcript distributions are critical resources to complement genomic sequence data and to correlate functional and genetic brain architecture. Here we describe the generation and analysis of a transcrip

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http://www.ncbi.nlm.nih.gov/pubmed/22996553

Valproate Increases Glutaminase and Decreases Glutamine Synthetase Activities in Primary Cultures of Rat Brain Astrocytes

Autor: H. Ronald Zielke, Robert C. Woody, R. M. Collins

Publikováno v: Journal of Neurochemistry. 62:1137-1143

It has been proposed that hyperammonemia may be associated with valproate therapy. As astrocytes are the primary site of ammonia detoxification in brain, the effects of valproate on glutamate and glutamine metabolism in astrocytes were studied. It is

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https://doi.org/10.1046/j.1471-4159.1994.62031137.x