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Akademický článek
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Autor:
H. Rommelspacher, A. Kraschewski, Catrin Wernicke, Juergen Gallinat, Georg Winterer, J. Reese
Publikováno v:
Pharmacopsychiatry. 42:41-50
Introduction: Dopamine systems in the CNS are decisively implicated in the motivational and rewarding properties of nicotine. The dopamine D2 receptor (DRD2) plays a pivotal role by promoting these properties, making this gene a good candidate for as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144a74d63ef1a1c8a77f790190020091
https://doi.org/10.1055/s-0028-1085444
https://doi.org/10.1055/s-0028-1085444
Publikováno v:
Acta Neurologica Scandinavica. 92:451-454
Several lines of evidence suggest that endogenous and exogenous toxins may play a major role in the pathogenesis of Parkinson's disease (PD). In vivo aromatic beta-carbolines, like harman or norharman, may easily be formed by cyclization of indoleami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f29b33a8b243cbf20dbe17ebfd24cfc
https://doi.org/10.1111/j.1600-0404.1995.tb00479.x
https://doi.org/10.1111/j.1600-0404.1995.tb00479.x
Publikováno v:
Pharmacopsychiatry. 40:191-195
Introduction Genetic variations of the serotonin transporter-linked polymorphic region (5-HTTLPR) have been implicated in the pathogenesis of several psychiatric disorders. Recent evidence indicates that the biallelic polymorphic region (S and L alle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65d930d87e3c617241c99b6e022c6dd
https://doi.org/10.1055/s-2007-984464
https://doi.org/10.1055/s-2007-984464
Autor:
Jerzy Samochowiec, Lutz G. Schmidt, Werner Herrmann, Richard Mahlberg, Michael N. Smolka, M. Ziller, Georg Winterer, Thomas Sander, H. Rommelspacher
Publikováno v:
Behavior Genetics. 33:7-15
Based on pharmacologic evidence, it has been suggested that GABAB receptors may play a crucial role in the generation of alpha-electroencephalogram (EEG) oscillations. We tested whether three exonic variants of the gene encoding the human GABAB recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb4d17f706194baab8abd3ca3bae6b3c
https://doi.org/10.1023/a:1021043315012
https://doi.org/10.1023/a:1021043315012
Publikováno v:
Comprehensive Psychiatry, Vol 41, Iss 2, Pp 90-94 (2000)
The transition to alcohol dependence is supposed to occur during a critical period that begins with increased drinking and ends with a loss of control. This process may last about 3 to 4 years, and is modified by gender and accelerated by premorbid t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5077241cf9b446ed61f5b1f7270e48e
http://www.sciencedirect.com/science/article/pii/S0010440X00800140
http://www.sciencedirect.com/science/article/pii/S0010440X00800140
Autor:
Wilfried Kuhn, Horst Przuntek, S. Sällström Baum, P. Häussermann, Thomas Müller, Dirk Woitalla, H. Rommelspacher
Publikováno v:
Journal of Neural Transmission. 105:239-246
An augmented synthesis of tetrahydroisoquinolines, such as salsolinol (SAL) or an increased N-methylation of these compounds has been addressed by various investigators as putative pathophysiologic mechanisms in Parkinson's disease (PD). Aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b895268a7cde0cbbbc6b90ae891febd
https://doi.org/10.1007/s007020050052
https://doi.org/10.1007/s007020050052
Publikováno v:
American Journal of Medical Genetics. 74:483-487
A dysfunction of dopaminergic neurotansmission has been implicated in alcohol-seeking behavior. Recently, a significant association between the seven-repeat allele (DRD4*7R) of a 16 amino acid motif in the third exon of the dopamine D4 receptor gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3edc0dd4e1ddf8a6b71bc3dec2b996e1
https://doi.org/10.1002/(sici)1096-8628(19970919)74:5<483::aid-ajmg5>3.0.co
https://doi.org/10.1002/(sici)1096-8628(19970919)74:5<483::aid-ajmg5>3.0.co
Autor:
H. Rommelspacher, Michael N. Smolka, Juergen Gallinat, Undine E. Lang, M. Staedtgen, Georg Juckel, Catrin Wernicke, Richard Mahlberg, J. Eggers, Dieter Kunz, Peter Kalus
Publikováno v:
Pharmacopsychiatry. 38:158-160
Background: Cigarette smoking has been associated with mood enhancing properties and modulating effects on serotonin activity. The loudness dependence (LD) of the auditory-evoked N1/ P2-component has been related to serotonergic neurotransmission, i.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342e026c066d4cfcc3093ba5f5862676
https://doi.org/10.1055/s-2005-871237
https://doi.org/10.1055/s-2005-871237