Zobrazeno 1 - 10 of 179 pro vyhledávání: '"H Rokos"'
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Different Tissue Distribution, Elimination, and Kinetics of Thyroxine and Its Conformational Analog, the Synthetic Flavonoid EMD 49209 in the Rat1
Autor: J.P. Schröder-van der Elst, H. Rokos, Josef Köhrle, G. Morreale de Escobar, D. van der Heide
Publikováno v: Endocrinology. 138:79-84
The synthetic flavonoids EMD 23188 and EMD 49209, developed as T4 analogs, displace T4 from transthyretin, and in vitro they inhibit 5′-deiodinase activity. In vivo EMD 21388 causes tissue-specific changes in thyroid hormone metabolism. In tissues
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2cb6e88a87ac98c14245df5d256dd080
https://doi.org/10.1210/endo.138.1.4848
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8
H(2)O(2) increases de novo synthesis of (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin via GTP cyclohydrolase I and its feedback regulatory protein in vitiligo
Autor: B, Chavan, W, Beazley, J M, Wood, H, Rokos, H, Ichinose, K U, Schallreuter
Publikováno v: Journal of inherited metabolic disease. 32(1)
Patients with vitiligo accumulate up to 10(-3) mol/L concentrations of H(2)O(2) in their epidermis, which in turn affects many metabolic pathways in this compartment, including the synthesis and recycling of the cofactor (6R)-L-erythro-5,6,7,8-tetrah
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::70632cb4fa6dbf1796f3d99f5eb1ca5c
https://pubmed.ncbi.nlm.nih.gov/19101819
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9
Selective affinity labeling of a 27-kDa integral membrane protein in rat liver and kidney with N-bromoacetyl derivatives of L-thyroxine and 3,5,3'-triiodo-L-thyronine
Autor: Jack L. Leonard, Josef Köhrle, Ulla B. Rasmussen, Rolf-Dieter Hesch, H. Rokos
Publikováno v: Journal of Biological Chemistry. 265:6146-6154
125I-Labeled N-bromoacetyl derivatives of L-thyroxine and L-triiodothyronine were used as alkylating affinity labels to identify rat liver and kidney microsomal membrane proteins which specifically bind thyroid hormones. Affinity label incorporation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f217c40c2b07542301ac7b34c5e0aca1
https://doi.org/10.1016/s0021-9258(19)39304-4
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Plný text Recenzováno Digitální knihovna AV ČR
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