Zobrazeno 1 - 10
of 2 184
pro vyhledávání: '"H Reynolds"'
Autor:
Lynne Krohn, Karl Heilbron, Cornelis Blauwendraat, Regina H. Reynolds, Eric Yu, Konstantin Senkevich, Uladzislau Rudakou, Mehrdad A. Estiar, Emil K. Gustavsson, Kajsa Brolin, Jennifer A. Ruskey, Kathryn Freeman, Farnaz Asayesh, Ruth Chia, Isabelle Arnulf, Michele T. M. Hu, Jacques Y. Montplaisir, Jean-François Gagnon, Alex Desautels, Yves Dauvilliers, Gian Luigi Gigli, Mariarosaria Valente, Francesco Janes, Andrea Bernardini, Birgit Högl, Ambra Stefani, Abubaker Ibrahim, Karel Šonka, David Kemlink, Wolfgang Oertel, Annette Janzen, Giuseppe Plazzi, Francesco Biscarini, Elena Antelmi, Michela Figorilli, Monica Puligheddu, Brit Mollenhauer, Claudia Trenkwalder, Friederike Sixel-Döring, Valérie Cochen De Cock, Christelle Charley Monaca, Anna Heidbreder, Luigi Ferini-Strambi, Femke Dijkstra, Mineke Viaene, Beatriz Abril, Bradley F. Boeve, andMe Research Team, Sonja W. Scholz, Mina Ryten, Sara Bandres-Ciga, Alastair Noyce, Paul Cannon, Lasse Pihlstrøm, Mike A. Nalls, Andrew B. Singleton, Guy A. Rouleau, Ronald B. Postuma, Ziv Gan-Or
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
REM-sleep behavior disorder often precedes Parkinson’s disease or dementia. Here, the authors perform a genome-wide association study for REM-sleep behavior disorder, and discover how it potentially affects gene expression in the brain.
Externí odkaz:
https://doaj.org/article/59eca1d6c47b4c98aed465f4c7a60228
Autor:
Tripti Shrestha Bhattarai, Tambudzai Shamu, Alexander N. Gorelick, Matthew T. Chang, Debyani Chakravarty, Elena I. Gavrila, Mark T. A. Donoghue, JianJong Gao, Swati Patel, Sizhi Paul Gao, Margaret H. Reynolds, Sarah M. Phillips, Tara Soumerai, Wassim Abida, David M. Hyman, Alison M. Schram, David B. Solit, Lillian M. Smyth, Barry S. Taylor
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
How different oncogenic Akt mutants can affect the response to Akt inhibitors is currently unclear. Here, the authors analyse somatic mutations of Akt1-3 isoforms in several human cancers, investigate their oncogenic effects and therapeutic relevance
Externí odkaz:
https://doaj.org/article/2f4ee7e6727f4b59871619d4a10453d0
Autor:
Edward H Reynolds
Publikováno v:
Journal of the Royal Society of Medicine. 115(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970d101214b445413412890898e5d731
https://pubmed.ncbi.nlm.nih.gov/34663131
https://pubmed.ncbi.nlm.nih.gov/34663131
Autor:
Aine Fairbrother-Browne, Aminah T. Ali, Regina H. Reynolds, Sonia Garcia-Ruiz, David Zhang, Zhongbo Chen, Mina Ryten, Alan Hodgkinson
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Fairbrother-Browne and collaborators analyze the relationship between nuclear and mitochondrial gene expression across the human brain and find correlation profiles that are governed by regional patterns. They show that these correlations are disrupt
Externí odkaz:
https://doaj.org/article/d5dd7c062e3448ff913f17a96a81fd0a
Autor:
Zachary W. Davis, Gabriel B. Benigno, Charlee Fletterman, Theo Desbordes, Christopher Steward, Terrence J. Sejnowski, John H. Reynolds, Lyle Muller
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Spontaneous traveling cortical waves shape neural responses. Using a large-scale computational model, the authors show that transmission delays shape locally asynchronous spiking dynamics into traveling waves without inducing correlations and boost r
Externí odkaz:
https://doaj.org/article/03f4f65aa15d40559abd129057a7ae9b
Publikováno v:
The Lancet Global Health, Vol 10, Iss 10, Pp e1389- (2022)
Externí odkaz:
https://doaj.org/article/29baa7baeac643b4b0fc4a8c2c6d97bc
Autor:
Zhongbo Chen, David Zhang, Regina H. Reynolds, Emil K. Gustavsson, Sonia García-Ruiz, Karishma D’Sa, Aine Fairbrother-Browne, Jana Vandrovcova, International Parkinson’s Disease Genomics Consortium (IPDGC), John Hardy, Henry Houlden, Sarah A. Gagliano Taliun, Juan Botía, Mina Ryten
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Knowledge of genomic features specific to humans may be important for understanding disease. Here the authors demonstrate a potential role for these human-lineage-specific sequences in brain development and neurological disease.
Externí odkaz:
https://doaj.org/article/adb7017084874dddbf672c99a5595752
Autor:
Michael D. Erdman, Niloofar Kossari, Jessica Ye, Kristen H. Reynolds, Emily Blodget, B. Robert Mozayeni, Farshid Sam Rahbar
Publikováno v:
Journal of Patient-Centered Research and Reviews, Vol 8, Iss 1, Pp 39-47 (2021)
Background: In the clinical setting, it is not common practice to consider a vector bite, such as from a tick or flea, to be a contributing factor to chronic digestive symptoms. This article investigates associations we have observed among symptomati
Externí odkaz:
https://doaj.org/article/fbb171cd2c874a3699f0ade92e7841cc
Autor:
Sebastian Guelfi, Karishma D’Sa, Juan A. Botía, Jana Vandrovcova, Regina H. Reynolds, David Zhang, Daniah Trabzuni, Leonardo Collado-Torres, Andrew Thomason, Pedro Quijada Leyton, Sarah A. Gagliano Taliun, Mike A. Nalls, International Parkinson’s Disease Genomics Consortium (IPDGC), UK Brain Expression Consortium (UKBEC), Kerrin S. Small, Colin Smith, Adaikalavan Ramasamy, John Hardy, Michael E. Weale, Mina Ryten
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Regulation of gene expression and splicing are thought to be tissue-specific. Here, the authors obtain genomic and transcriptomic data from putamen and substantia nigra of 117 neurologically healthy human brains and find that splicing eQTLs are enric
Externí odkaz:
https://doaj.org/article/d83bf92ed8ef48c8b17db5f5eae7d0d7
Autor:
Basil George Verghese, Sanjana Kalvehalli Kashinath, Nagesh Jadhav, Sohni Reddy, Konara Sachith Bandara, Tara Chen, Carl H. Reynolds
Publikováno v:
Journal of Community Hospital Internal Medicine Perspectives, Vol 10, Iss 1, Pp 1-5 (2020)
Background Several studies have demonstrated a patient preference for physicians wearing a white coat associated with improved patient satisfaction. There are few studies on physicians’ perceptions of attire mainly done in the outpatient and surgic
Externí odkaz:
https://doaj.org/article/a1c1fea9f0284a6eb609359bfc307f4f