Zobrazeno 1 - 10
of 27
pro vyhledávání: '"H R Masure"'
Publikováno v:
Molecular Microbiology. 27:929-939
Transformation in bacteria is the uptake and incorporation of exogenous DNA into a cell's genome. Several species transform naturally during a regulated state defined as competence. Genetic elements in Streptococcus pneumoniae induced during transfor
Autor:
P Ryan, S. Johnson, H R Masure, A Ortqvist, Carsten I. Rosenow, P. A. Fontán, Jeffrey N. Weiser
Publikováno v:
Molecular Microbiology. 25:819-829
The surface of Streptococcus pneumoniae is decorated with a family of choline-binding proteins (CBPs) that are non-covalently bound to the phosphorylcholine of the teichoic acid. Two examples (PspA, a protective antigen, and LytA, the major autolysin
Autor:
H R Masure, Elaine Tuomanen
Publikováno v:
Microbial Drug Resistance. 3:297-308
Autor:
Herbert Weissbach, Nathan Brot, Cindy Grove Arvidson, Diana R. Cundell, B. J. Pearce, T M Wizemann, Magdalene So, Jackob Moskovitz, H R Masure
Publikováno v:
Proceedings of the National Academy of Sciences. 93:7985-7990
Pathogenic bacteria rely on adhesins to bind to host tissues. Therefore, the maintenance of the functional properties of these extracellular macromolecules is essential for the pathogenicity of these microorganisms. We report that peptide methionine
Autor:
Diana R. Cundell, Barbara Spellerberg, Ilona Idanpaan-Heikkila, B. J. Pearce, J. Sandros, H R Masure, Carsten I. Rosenow
Publikováno v:
Molecular Microbiology. 19:803-813
Pneumococcus has been shown to bind to epithelial cells of the nasopharynx and lung, and to endothelial cells of the peripheral vasculature. To characterize bacterial elements required for attachment to these cell types, a library of genetically alte
Publikováno v:
New England Journal of Medicine. 332:1280-1284
The study of Streptococcus pneumoniae has led to many insights into the pathogenesis of bacterial infections. The importance of the polysaccharide capsule of the organism in determining its virulence was indicated by studies of the protective role of
Publikováno v:
Molecular Microbiology. 12:881-892
To identify elements participating in the process of transformation, a bank of genetically altered mutants of Streptococcus pneumoniae with defects in exported proteins was assessed for a decrease in transformation efficiency. One mutant consistently
Publikováno v:
Infection and Immunity. 62:2582-2589
When colonies of encapsulated isolates of Streptococcus pneumoniae are viewed with oblique, transmitted light on a transparent surface, they are heterogeneous in appearance because of variation in opacity. There is spontaneous phase variation among a
Publikováno v:
Molecular Microbiology. 9:1037-1050
A strategy was developed to mutate and genetically identify exported proteins in Streptococcus pneumoniae. Vectors were created and used to screen pneumococcal DNA in Escherichia coli and S. pneumoniae for translational gene fusions to alkaline phosp
Publikováno v:
Infection and Immunity. 61:2780-2785
The adherence of Bordetella pertussis to ciliated cells and macrophages is critical to colonization and infection of the respiratory tract. Adherence to both types of cells involves the recognition of eukaryotic carbohydrates by the bacterial adhesin