Výsledky vyhledávání - "H R Herschman"

Cloning and characterization of the human granulocyte chemotactic protein-2 gene

Autor: L E Rovai, H R Herschman, J B Smith

Publikováno v: The Journal of Immunology. 158:5257-5266

We recently described a novel murine CXC chemokine, designated lipopolysaccharide-induced CXC chemokine (LIX). In an ongoing search for new human chemokines related to LIX, we cloned the gene for human granulocyte chemotactic protein-2 (GCP-2) as wel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e56743978ad6ebddbc7754827150764
https://doi.org/10.4049/jimmunol.158.11.5257

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Prostaglandin synthase 1 and prostaglandin synthase 2 both participate in activation-induced prostaglandin D2 production in mast cells

Autor: R Kawata, S T Reddy, B Wolner, H R Herschman

Publikováno v: The Journal of Immunology. 155:818-825

Activation of MMC-34 cells, a murine mast cell line, or bone marrow-derived mast cells by aggregation of IgE cell surface receptors or addition of calcium ionophore stimulates prostaglandin (PG) D2 synthesis and secretion. An initial rapid burst of P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ace48e0c958a35b75b93a1c5c819e37b
https://doi.org/10.4049/jimmunol.155.2.818

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Synaptotagmin IV: biochemistry, genetics, behavior, and possible links to human psychiatric disease

Autor: G D, Ferguson, L, Vician, H R, Herschman

Publikováno v: Molecular neurobiology. 23(2-3)

We isolated the rat synaptotagmin IV (Syt IV) cDNA in a screen for sequences that are specifically induced in neuronal cells. The Syts are a large family of genes thought to mediate synaptic function. Syt IV is brain-specific, induced in hippocampus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f0a8ab5a5c8dd20319a1d7ff59a07a8b
https://pubmed.ncbi.nlm.nih.gov/11817218

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Human pharmacokinetic and dosimetry studies of [(18)F]FHBG: a reporter probe for imaging herpes simplex virus type-1 thymidine kinase reporter gene expression

Autor: S, Yaghoubi, J R, Barrio, M, Dahlbom, M, Iyer, M, Namavari, N, Satyamurthy, R, Goldman, H R, Herschman, M E, Phelps, S S, Gambhir

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(8)

9-[4-[(18)F]fluoro-3-(hydroxymethyl)butyl]guanine ([(18)F]FHBG) has been used as a reporter probe to image expression of herpes simplex virus type-1 thymidine kinase (HSV1-tk) reporter gene in living animals. Our aim was to study the kinetics, biodis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dbf4a2fe0273a399afd7e7724514364c
https://pubmed.ncbi.nlm.nih.gov/11483685

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8-[18F]Fluoropenciclovir: an improved reporter probe for imaging HSV1-tk reporter gene expression in vivo using PET

Autor: M, Iyer, J R, Barrio, M, Namavari, E, Bauer, N, Satyamurthy, K, Nguyen, T, Toyokuni, M E, Phelps, H R, Herschman, S S, Gambhir

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(1)

We have synthesized and evaluated 8-[18F]fluoropenciclovir (FPCV) and compared it with 8-[18F]fluoroganciclovir (FGCV) for monitoring the expression of herpes simplex virus type 1 thymidine kinase (HSV1 -tk) reporter gene in cell culture and in vivo.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d3ec29da0e7800f229b837962a402a11
https://pubmed.ncbi.nlm.nih.gov/11197957

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Expression of the urokinase plasminogen activator receptor is transiently required during 'priming' of PC12 cells in nerve growth factor-directed cellular differentiation

Autor: R, Farias-Eisner, L, Vician, S, Reddy, R, Basconcillo, S A, Rabbani, Y Y, Wu, R A, Bradshaw, H R, Herschman

Publikováno v: Journal of neuroscience research. 63(4)

We previously identified the urokinase plasminogen activator receptor (UPAR) as a gene induced by nerve growth factor (NGF), but not by epidermal growth factor (EGF), in PC12 cells (Farias-Eisner et al. [2000] J. Neurosci. 20:230-239). Antisense olig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::412c9bd2fdf7a0b4a5adf52933204bd2
https://pubmed.ncbi.nlm.nih.gov/11170184

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Searching for depolarization-induced genes that modulate synaptic plasticity and neurotrophin-induced genes that mediate neuronal differentiation

Autor: H R, Herschman, G D, Ferguson, J D, Feldman, R, Farias-Eisner, L, Vician

Publikováno v: Neurochemical research. 25(5)

We identify and characterize two classes of immediate-early genes: (i) genes, induced by depolarization in neurons, that play a role in depolarization-induced neuronal plasticity and (ii) genes, induced in neuronal precursors by neurotrophins, that p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1d5ee22cf98af3b8c17467a06d331e3
https://pubmed.ncbi.nlm.nih.gov/10905620

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Imaging of adenoviral-directed herpes simplex virus type 1 thymidine kinase reporter gene expression in mice with radiolabeled ganciclovir

Autor: S S, Gambhir, J R, Barrio, L, Wu, M, Iyer, M, Namavari, N, Satyamurthy, E, Bauer, C, Parrish, D C, MacLaren, A R, Borghei, L A, Green, S, Sharfstein, A J, Berk, S R, Cherry, M E, Phelps, H R, Herschman

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(11)

We are developing procedures to repeatedly and noninvasively image the expression of transplanted reporter genes in living animals and in patients, using PET. We have investigated the use of the Herpes Simplex Virus type 1 thymidine kinase gene (HSV1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8958fd919f9320ab39671e4d5c99630a
https://pubmed.ncbi.nlm.nih.gov/9829598

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