Zobrazeno 1 - 10
of 135
pro vyhledávání: '"H R, Heyman"'
Autor:
Conway Rg, H. R. Heyman, Denissen Jf, George S. Sheppard, George M. Carrera, Douglas W. Morgan, T. J. Magoc, Daniel H. Albert, Lianhong Xu, Florjancic As, Steven K. Davidsen, Michael L. Curtin, Robert B. Garland, Douglas H. Steinman, Paul Tapang, Luo G, Rhein Da, James B. Summers, Trautmann Ja, Kennan C. Marsh
Publikováno v:
Journal of Medicinal Chemistry. 41:74-95
Studies conducted with the goal of discovering a second-generation platelet-activating factor (PAF) antagonist have identified a novel class of potent and orally active antagonists which have high aqueous solubility and long duration of action in ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4a87f7d36ac474f481924621ee6e2a6
https://doi.org/10.1021/jm970389+
https://doi.org/10.1021/jm970389+
Autor:
H. R. Heyman, George W. Carter, Steven K. Davidsen, Conway Rg, T. J. Magoc, James B. Summers, James H. Holms, Rhein Da, Daniel H. Albert
Publikováno v:
Journal of Medicinal Chemistry. 37:4423-4429
Pyrrolothiazole 4 is a potent antagonist of platelet activating factor-mediated effects in a variety of in vitro and in vivo assays. Despite its positive activity in models of inflammation and septic shock, 4 lacks the aqueous solubility necessary fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0b5adaa68fa57c4cda5a93233ea11e
https://doi.org/10.1021/jm00052a001
https://doi.org/10.1021/jm00052a001
Autor:
G. M. Jun. Carrera, T. J. Magoc, William C. Calhoun, Daisy Pireh, H. R. Heyman, Rhein Da, S. K. Davidsen, Paul D. May, Richard G. Conway, James B. Summers, Denise E. Guinn, James G. Phillips, George W. Carter, G. S. Sheppard, Daniel H. Albert, D. H. Steinman, M. G. Bures
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9da27a79fd4362f079e8a53d75ae9d0
https://doi.org/10.1002/chin.199450141
https://doi.org/10.1002/chin.199450141
Autor:
Daisy Pireh, James H. Holms, Daniel H. Albert, T. J. Magoc, G. M. Jun. Carrera, G. S. Sheppard, D. H. Steinman, Rhein Da, H. R. Heyman, Paul Tapang, S. K. Davidsen, Richard G. Conway, James B. Summers, Michael L. Curtin
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28b1a02626b4f7b7ba3e0064000ceb8c
https://doi.org/10.1002/chin.199614129
https://doi.org/10.1002/chin.199614129
Autor:
M L, Curtin, S K, Davidsen, H R, Heyman, R B, Garland, G S, Sheppard, A S, Florjancic, L, Xu, G M, Carrera, D H, Steinman, J A, Trautmann, D H, Albert, T J, Magoc, P, Tapang, D A, Rhein, R G, Conway, G, Luo, J F, Denissen, K C, Marsh, D W, Morgan, J B, Summers
Publikováno v:
Journal of medicinal chemistry. 41(1)
Studies conducted with the goal of discovering a second-generation platelet-activating factor (PAF) antagonist have identified a novel class of potent and orally active antagonists which have high aqueous solubility and long duration of action in ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bb2c074df0fa0c2bbeaf883649b3410
https://pubmed.ncbi.nlm.nih.gov/9438024
https://pubmed.ncbi.nlm.nih.gov/9438024
Autor:
H. R. Heyman, Daniel H. Albert, T. J. Magoc, Denise E. Guinn, Rhein Da, Conway Rg, George W. Carter, James B. Summers
Publikováno v:
Journal of medicinal chemistry. 35(11)
A class of N-substituted tetrahydrobenzopyrano[3,4-c]pyridines, I, have been identified as antagonists of platelet activating factor (PAF). The structural features essential for PAF binding were determined by systematic modification of three sites in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee8335a8f57fbe42625cc63bb393e3c
https://pubmed.ncbi.nlm.nih.gov/1317924
https://pubmed.ncbi.nlm.nih.gov/1317924
Autor:
Barman, Dhiraj1 (AUTHOR), Rath, Suchismita1 (AUTHOR), Kumar Ravva, Mahesh2 (AUTHOR), Jacob, Jesni M.2 (AUTHOR), Sen, Subhabrata1 (AUTHOR) Subhabrata.sen@snu.edu.in
Publikováno v:
Advanced Synthesis & Catalysis. Dec2023, Vol. 365 Issue 23, p4216-4226. 11p.
Autor:
Sang, Ji‐Wei1,2 (AUTHOR), Du, Peiyu1,2 (AUTHOR), Xia, Dingding1,2 (AUTHOR), Zhang, Yu3 (AUTHOR) yzhang@shutcm.edu.cn, Wang, Jinxin1 (AUTHOR) jxwang2013@126.com, Zhang, Wei‐Dong1,2,3 (AUTHOR) wdzhangy@hotmail.com
Publikováno v:
Chemistry - A European Journal. Aug2023, Vol. 29 Issue 43, p1-8. 8p.
Autor:
Matore, Balaji Wamanrao1 (AUTHOR), Banjare, Purusottam1 (AUTHOR), Sarthi, Ajay Singh2 (AUTHOR), Roy, Partha Pratim1 (AUTHOR), Singh, Jagadish1 (AUTHOR) jagadish.singh@ggu.ac.in
Publikováno v:
ChemistrySelect. 3/6/2023, Vol. 8 Issue 9, p1-15. 15p.
Publikováno v:
Organic & Biomolecular Chemistry; 5/7/2024, Vol. 22 Issue 17, p3459-3467, 9p