Zobrazeno 1 - 10
of 140
pro vyhledávání: '"H Paul Redmond"'
Autor:
Xuqin Chen, Yan Li, Siobhan Blankson, Min Liu, Danping Huang, H Paul Redmond, Jing Huang, Jiang Huai Wang, Jian Wang
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0171146 (2017)
The costimulatory protein B7-H3 has been shown to play a contributory role in the development and progression of experimental pneumococcal meningitis by augmentation of the innate immunity-associated inflammatory response via a TLR2-dependent manner.
Externí odkaz:
https://doaj.org/article/4249f4f282294fd993c0336da11c7a25
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62232 (2013)
TLR signaling is a crucial component of the innate immune response to infection. MicroRNAs (miRNAs) have been shown to be upregulated during TLR signaling. Specifically, microRNA-146a (miR-146a) plays a key role in endotoxin tolerance by downregulati
Externí odkaz:
https://doaj.org/article/c7364cea925542319e41894169d59905
Autor:
D Peter O'Leary, Lavinia Bhatt, John F Woolley, David R Gough, Jiang H Wang, Thomas G Cotter, H Paul Redmond
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e44176 (2012)
Surgery induced inflammation is a potent promoter of tumour recurrence and metastasis in colorectal cancer. The recently discovered family of Nox enzymes represent a major source of endogenous reactive oxygen species (ROS) and are now heavily implica
Externí odkaz:
https://doaj.org/article/9a69a4d32b7b499c8cd8e8bc1ce3e18c
Autor:
Huiting Zhou, Xiaying Lu, Jie Huang, Patrick Jordan, Shurong Ma, Lingqi Xu, Fangjie Hu, Huan Gui, He Zhao, Zhenjiang Bai, H Paul Redmond, Jiang Huai Wang, Jian Wang
Publikováno v:
Journal of Inflammation Research. 15:3829-3845
Huiting Zhou,1,* Xiaying Lu,2,3,* Jie Huang,1,* Patrick Jordan,2 Shurong Ma,1 Lingqi Xu,1 Fangjie Hu,1 Huan Gui,1 He Zhao,1 Zhenjiang Bai,1 H Paul Redmond,2 Jiang Huai Wang,2 Jian Wang1 1Institute of Pediatric Research, Childrenâs Ho
Autor:
Seamus O'Reilly, Hailey Kathryn Carroll, Deirdre Murray, Louise Burke, Triona McCarthy, Robert O’Connor, Claire Kilty, Sonya Lynch, Jennifer Feighan, Maeve Cloherty, Patricia Fitzpatrick, Katrina Falvey, Verena Murphy, Mary Jane O'Leary, Sophie Gregg, Leonie Young, Eilish McAuliffe, Josephine Hegarty, Anna Gavin, Mark Lawler, Paul Kavanagh, Susan Spillane, Terry McWade, Mairead Heffron, Karen Ryan, Paul J Kelly, Aileen Murphy, Mark Corrigan, H. Paul Redmond, Patrick Redmond, Paul M Walsh, Paula Tierney, Mengyang Zhang, Kathleen Bennett, Maeve Mullooly
Publikováno v:
Journal of Cancer Policy. 36:100414
Autor:
D. Peter O’Leary, Jiang Huai Wang, H. Paul Redmond, Rolf W. Pfirrmann, Mark Corrigan, M. Jinih
Publikováno v:
Anticancer Research. 41:2247-2256
Background/aim Adjuvant therapeutic options are limited for triple negative breast cancer (TNBC). Thus, we evaluated the cytotoxic effects of the newly synthesized antineoplastic agent 1,4,5-Oxathiazinane-4,4-dioxide (OTD) on TNBC cells as a potentia
Autor:
Jie Huang, Michael Ita, Huiting Zhou, He Zhao, Fara Hassan, Zhenjiang Bai, D. Peter O’Leary, Yiping Li, H. Paul Redmond, Jiang Huai Wang, Jian Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Sepsis, septic shock, and their sequelae are the leading causes of death in intensive care units, with limited therapeutic options. Disease resistance and tolerance are two evolutionarily conserved yet distinct defense strategies that protect the hos
Purpose: Metabolomic analysis in colorectal cancer (CRC) is an emerging research area with both prognostic and therapeutic targeting potential. We aimed to identify metabolomic pathway activity prognostic for CRC recurrence and overall survival and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebf9fd2172848cc371106e5a5e662d6
https://hdl.handle.net/10468/12941
https://hdl.handle.net/10468/12941
Publikováno v:
Journal of gastrointestinal cancer.
Metabolomic analysis in colorectal cancer (CRC) is an emerging research area with both prognostic and therapeutic targeting potential. We aimed to identify metabolomic pathway activity prognostic for CRC recurrence and overall survival and cross-refe
Autor:
Yanhong Li, He Zhao, Zhimin Yin, Gang Li, Ming Wu, Zhihui Zhao, Jian Wang, Yi-Ping Li, Jiang Huai Wang, Huan Gui, H. Paul Redmond, Huiting Zhou, Zhenjiang Bai
Publikováno v:
The Journal of Immunology. 200:1771-1780
High mobility group box 1 (HMGB1), a chromatin-binding nuclear protein, plays a critical role in sepsis by acting as a key “late-phase” inflammatory mediator. Integrin CD11b is essential for inflammatory cell activation and migration, thus mediat