Zobrazeno 1 - 10
of 82
pro vyhledávání: '"H P Lehmann"'
Autor:
Xinyi Wei, MSc, Sabine Weber, MD, Decheng Yin, MSc, Ida Allabauer, Tilman Jobst-Schwan, MD, Michael Wiesener, MD, Mario Schiffer, MD, Diana Dudziak, PhD, Christian H. K. Lehmann, PhD, Joachim Woelfle, MD, Andre Hoerning, MD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1666 (2024)
Background. The mammalian target of rapamycin inhibitor (mTORi) therapy after kidney transplantation is solely monitored pharmacokinetically, not necessarily reflecting PI3K-Akt-mTOR pathway blockade efficacy leading to potential under-or overimmunos
Externí odkaz:
https://doaj.org/article/701e3fa629a94ad99b283dc1d0ebf8a1
Autor:
T. Kruse, S. Shamai, D. Leflerovà, B. Wirth, R. Heller, N. Schloss, H. C. Lehmann, S. Brakemeier, T. Hagenacker, B. Braumann, G. Wunderlich
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Impairment of bulbar function in adult individuals with spinal muscular atrophy (SMA) usually is not assessed by established motor scores. Measurements of oral function including quantitative muscle and endurance tests are able to
Externí odkaz:
https://doaj.org/article/f769be16aba6402a9d9e336308e5e279
Autor:
Yihua Bei, Chen Chen, Xuejiao Hua, Mingming Yin, Xiangmin Meng, Zhenzhen Huang, Weitong Qi, Zhuhua Su, Chang Liu, H. Immo Lehmann, Guoping Li, Yu Huang, Junjie Xiao
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Neonatal mouse heart can regenerate after left ventricle (LV) apical resection (AR). Since current AR rodent method is accomplished by resecting LV apex until exposure of LV chamber, it is relatively difficult to operate reproducibly. We aim
Externí odkaz:
https://doaj.org/article/edc4514f8ef54f1596a99a105407884a
Autor:
Yan Qiu, Benjamin Fernández-García, H. Immo Lehmann, Guoping Li, Guido Kroemer, Carlos López-Otín, Junjie Xiao
Publikováno v:
Journal of Sport and Health Science, Vol 12, Iss 1, Pp 8-35 (2023)
Exercise has long been known for its active role in improving physical fitness and sustaining health. Regular moderate-intensity exercise improves all aspects of human health and is widely accepted as a preventative and therapeutic strategy for vario
Externí odkaz:
https://doaj.org/article/13a5f00e7d88481b96a4cfd8261a7d3f
Autor:
Lijun Wang, Jiaqi Wang, Pujiao Yu, Jingyi Feng, Gui-e Xu, Xuan Zhao, Tianhui Wang, H. Immo Lehmann, Guoping Li, Joost P. G. Sluijter, Junjie Xiao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
The benefit of regular exercise on the heart has been well documented but the role of RNA m6A modification in exercise-induced cardiac remodelling remains largely unknown. In this study, the authors report that METTL14 plays an important role in RNA
Externí odkaz:
https://doaj.org/article/f3bda8f19ff54730a4083c563cec8318
Autor:
E. Mauro, D. Lapaillerie, C. Tumiotto, C. Charlier, F. Martins, S. F. Sousa, M. Métifiot, P. Weigel, K. Yamatsugu, M. Kanai, H. Munier-Lehmann, C. Richetta, M. Maisch, J. Dutrieux, J. Batisse, M. Ruff, O. Delelis, P. Lesbats, V. Parissi
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Infection by retroviruses as HIV-1 requires the stable integration of their genome into the host cells. This process needs the formation of integrase (IN)-viral DNA complexes, called intasomes, and their interaction with the target DNA wrapp
Externí odkaz:
https://doaj.org/article/0734eb831b624bb0933a71194b76d6dc
Autor:
Rui Chen, Tingting Yang, Bing Jin, Wanru Xu, Yuwei Yan, Nathanael Wood, H. Immo Lehmann, Siqi Wang, Xiaolan Zhu, Weilin Yuan, Hongjian Chen, Zhengyu Liu, Guoping Li, T. Scott Bowen, Jin Li, Junjie Xiao
Publikováno v:
Advanced Science, Vol 10, Iss 17, Pp n/a-n/a (2023)
Abstract Skeletal muscle atrophy is a common clinical feature of many acute and chronic conditions. Circular RNAs (circRNAs) are covalently closed RNA transcripts that are involved in various physiological and pathological processes, but their role i
Externí odkaz:
https://doaj.org/article/0064d41c92584bcabb40bbc93a1ec784
Autor:
Juan Zhao, Ye Yu, Xiaolan Zhu, Yuling Xie, Songwei Ai, H. Immo Lehmann, Xuan Deng, Feifei Hu, Guoping Li, Yong Zhou, Junjie Xiao
Publikováno v:
MedComm, Vol 4, Iss 2, Pp n/a-n/a (2023)
Abstract Commonly used prediction models have been primarily constructed without taking physical activity into account. Using the Kailuan physical activity cohorts from Asymptomatic Polyvascular Abnormalities in Community (APAC) study, we developed a
Externí odkaz:
https://doaj.org/article/64eb523e84bb441ab61494993d74dde0
Autor:
H. Immo Lehmann, Krishan Sharma, Roma Bhatia, Theresa Mills, Joshua Lang, Guoping Li, Carl Andrews, Jay Cullivan, Jagmeet Singh, Theofanie Mela
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 3 (2023)
Background Remote monitoring (RM) of cardiac implantable electronic devices has been shown to improve cardiovascular morbidity and mortality. To date, no studies have investigated disparities in use and delivery of RM. This study was performed to inv
Externí odkaz:
https://doaj.org/article/b7b31baa64de4421a34de0ea384f2275
Autor:
Jian Fu, Christian H. K. Lehmann, Xinning Wang, Mandy Wahlbuhl, Ida Allabauer, Benjamin Wilde, Lukas Amon, Sebastian Dolff, Robert Cesnjevar, Andreas Kribben, Joachim Woelfle, Wolfgang Rascher, Peter F. Hoyer, Diana Dudziak, Oliver Witzke, André Hoerning
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Allograft-specific regulatory T cells (Treg cells) are crucial for long-term graft acceptance after transplantation. Although adoptive Treg cell transfer has been proposed, major challenges include graft-specificity and stability. Thus, ther
Externí odkaz:
https://doaj.org/article/aed570743c9f4d9fb446c26967b40fc2