Zobrazeno 1 - 6
of 6
pro vyhledávání: '"H P Brok"'
Autor:
Stefan Nierkens, Tonke K Raaijmakers, Renske J E van den Bijgaart, Martijn H den Brok, Melissa Wassink, Annemarie de Graaf, Jori A Wagenaars, Marleen Ansems, Gert Jan Scheffer, Gosse J Adema
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Tumor ablation techniques, like cryoablation, are successfully used in the clinic to treat tumors. The tumor debris remaining in situ after ablation is a major antigen depot, including neoantigens, which are presented by dendritic cells (D
Externí odkaz:
https://doaj.org/article/1d10133bed404d1486826c6a9612772a
Autor:
Martijn H. den Brok, Christian Büll, Melissa Wassink, Annemarie M. de Graaf, Jori A. Wagenaars, Marthe Minderman, Mayank Thakur, Sebastian Amigorena, Eric O. Rijke, Carla C. Schrier, Gosse J. Adema
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Saponin-based adjuvants are being explored as vaccine components as they induce high levels of antigen cross-presentation, but it is unknown how. Here the authors show that these adjuvants enhance cross-presentation by driving production of lipid bod
Externí odkaz:
https://doaj.org/article/5b83830e5f2e45ffac906cc79476ab4a
Autor:
Stefan Nierkens, Martijn H den Brok, Thijs Roelofsen, Jori A L Wagenaars, Carl G Figdor, Theo J Ruers, Gosse J Adema
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8368 (2009)
BackgroundThe TLR9 agonist CpG is increasingly applied in preclinical and clinical studies as a therapeutic modality to enhance tumor immunity. The clinical application of CpG appears, however, less successful than would be predicted from animal stud
Externí odkaz:
https://doaj.org/article/9b71579ac2cc4de8ab648b64648303bf
Publikováno v:
The Journal of Immunology. 151:6451-6459
Lethally irradiated C3H/Law mice were injected (i.v.) with C57BL/Rij allogeneic bone marrow cells to induce a delayed type graft-vs-host disease (GVHD). Signs of GVHD first became apparent in the third week after transplantation. The disease resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1fd27f5802273cea8dd4927a8110838
https://doi.org/10.4049/jimmunol.151.11.6451
https://doi.org/10.4049/jimmunol.151.11.6451
Publikováno v:
Immunological reviews. 183
The phylogenetic proximity between non-human primate species and humans is reflected by a high degree of immunological similarity. Non-human primates therefore provide important experimental models for disorders in the human population that are cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::283a807c3f2ef0aa383eee96cf3e6c24
https://pubmed.ncbi.nlm.nih.gov/11782256
https://pubmed.ncbi.nlm.nih.gov/11782256
Publikováno v:
Cytometry. 45(4)
New World monkeys are valuable animal models to study human diseases. To determine the phenotype of cells involved in immune responses, we used flow cytometry to screen a large panel of anti-human monoclonal antibodies (mAb) for cross-reactivity with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c54c76b2312f769c88adfcc01a8ada50
https://pubmed.ncbi.nlm.nih.gov/11746099
https://pubmed.ncbi.nlm.nih.gov/11746099