Zobrazeno 1 - 10
of 140
pro vyhledávání: '"H O Sjögren"'
Publikováno v:
The Journal of Immunology. 155:1132-1140
We have earlier shown that stimulation of human CD4+ T cells with SEA presented on Chinese hamster ovary (CHO)-DR transfectants coexpressing either B7 or LFA-3 resulted in distinct cytokine profiles. We now demonstrate that B7, but not LFA-3, strongl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::189a9914b6e3c76c38815bfb4441d0bb
https://doi.org/10.4049/jimmunol.155.3.1132
https://doi.org/10.4049/jimmunol.155.3.1132
Publikováno v:
The Journal of Immunology. 148:1993-1998
The role of the accessory molecule ICAM-1 in activation of subpopulations of human T cells was examined using the bacterial superantigen staphylococcal enterotoxin A (SEA) as a MHC class II and TCR-dependent polyclonal T cell activator. Human T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e54c9a76e7998fc25692ec40c58cf606
https://doi.org/10.4049/jimmunol.148.7.1993
https://doi.org/10.4049/jimmunol.148.7.1993
Autor:
G Hedlund, M Dohlsten, T Herrmann, G Buell, P A Lando, S Segrén, J Schrimsher, H R MacDonald, H O Sjögren, T Kalland
Publikováno v:
The Journal of Immunology. 147:4082-4085
Binding of staphylococcal enterotoxin A (SEA) to MHC class II encoded proteins is a prerequisite for its subsequent activation of a large fraction of T lymphocytes through interaction with variable segments of the TCR-beta chain. We cloned SEA in Esc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ac28e7882ee906a1e323199f365dde
https://doi.org/10.4049/jimmunol.147.12.4082
https://doi.org/10.4049/jimmunol.147.12.4082
Publikováno v:
The Journal of Immunology. 145:3767-3772
The lymphokines IL-2 and IL-4 promoted the growth of human PHA-triggered T cells, but only IL-2 induced the production of IFN-gamma and TNF. The addition of purified monocytes strongly enhanced the production of IFN-gamma in IL-2-stimulated T cell cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cab71d5ac1adda7f7902ab2758519a4
https://doi.org/10.4049/jimmunol.145.11.3767
https://doi.org/10.4049/jimmunol.145.11.3767
Autor:
C, Kjellman, S P, Olofsson, O, Hansson, T, Von Schantz, M, Lindvall, I, Nilsson, L G, Salford, H O, Sjögren, B, Widegren
Publikováno v:
International journal of cancer. 89(3)
Human gliomas express TGF-beta but, so far the expression of downstream mediators has been investigated in only a few cell lines. We have examined tissue specimens of 23 gliomas: 3 astrocytomas grade II (AST), 8 anaplastic astrocytomas grade III (AAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::285394ea34f6d893669885b80d587a95
https://pubmed.ncbi.nlm.nih.gov/10861501
https://pubmed.ncbi.nlm.nih.gov/10861501
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5
Extracorporeal whole blood immunoadsorption (ECIA) accelerates the clearance of radiolabeled monoclonal antibodies (mAbs) without significantly affecting tumor uptake by removing the excess of these mAbs from the blood, thus increasing tumor:normal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4833eee80aab326d828e326d590c1f2f
https://pubmed.ncbi.nlm.nih.gov/10541344
https://pubmed.ncbi.nlm.nih.gov/10541344
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(12)
Based on the biodistribution and kinetics of biotinylated 188Re-chimeric BR96 (chiBR96), the enhancement of the tumor-to-normal tissue (T/N) radioactivity ratio using extracorporeal immunoadsorption (ECIA) was evaluated and compared with that of avid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::edad878eec4b5bd7ed96776bae23e257
https://pubmed.ncbi.nlm.nih.gov/9430473
https://pubmed.ncbi.nlm.nih.gov/9430473
Publikováno v:
Cancer research. 57(20)
The internalizing monoclonal antibody BR96 was conjugated to the anticancer drug doxorubicin (DOX) using an acid-labile hydrazone bond to DOX and a thioether bond to the monoclonal antibody. The resulting conjugate, termed BR96-DOX, binds to a tumor-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::733f03436ddd1f517f214c86bacdf170
https://pubmed.ncbi.nlm.nih.gov/9377565
https://pubmed.ncbi.nlm.nih.gov/9377565
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 38(6)
This study investigates the efficacy of tumor radioimmunotargeting with 125I-labeled BR96-biotin monoclonal antibody using a new method, whole-blood immunoadsorption (WBIA), based on direct adsorption of unbound monoclonal antibody (MAb) from blood w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53cdf91d2fc408866cfbd8cc89b7d54f
https://pubmed.ncbi.nlm.nih.gov/9189138
https://pubmed.ncbi.nlm.nih.gov/9189138
Publikováno v:
Cancer research. 55
The present study investigates whether tumor:normal tissue uptake ratios of radiolabeled monoclonal antibodies can be further improved by a combination of extracorporeal immunoadsorption (ECIA) and preload with unlabeled idiotypic monoclonal antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2eded1ad6adea249b79038f76f60df9b
https://pubmed.ncbi.nlm.nih.gov/7493363
https://pubmed.ncbi.nlm.nih.gov/7493363