Zobrazeno 1 - 10
of 20
pro vyhledávání: '"H O, Voorma"'
Publikováno v:
The International journal of developmental biology. 44(8)
A number of growth factors, whose spatio-temporal expression is essential for embryonic development, are encoded by mRNAs with a complex 5'UTR. Human insulin-like growth factor 2 mRNA contains a long (592 nucleotides) 5'UTR (IGFl1) with one upstream
Publikováno v:
The International journal of developmental biology. 44(8)
The properties of the architecturally complex Xenopus laevis TGFbeta5, PDGF-A and PDGF-alpha receptor 5'UTRs were investigated. 5' extended cDNAs were obtained by 5'RACE, resulting in long 5'UTRs (478-710 nt) with multiple upstream AUGs (3-13), andth
Publikováno v:
Biochemistry international. 27(1)
Unwinding of double-stranded RNA by nuclear helicases can lead to modification of adenosine-residues, resulting in inosine. During initiation of protein synthesis the 5' untranslated region of an mRNA is unwound by eukaryotic initiation factors (eIF)
Publikováno v:
The Journal of biological chemistry. 267(11)
Two mechanisms of initiation of protein synthesis are known. The 5' cap-dependent model requires the activity of cap-binding eukaryotic initiation factors (eIF)1-4E and -4F, inducing unwinding of mRNA secondary structures. The internal initiation mod
Publikováno v:
The New biologist. 4(4)
Publikováno v:
The Journal of biological chemistry. 266(11)
We studied the mRNA-binding properties of eukaryotic initiation factor (eIF) 2. This Met-tRNA-binding factor interacts with the cap structure of reoviral mRNA in an ATP-independent manner. Both the beta- and gamma-subunit of eIF-2 are involved in the
Publikováno v:
The Journal of Immunology. 142:2847-2854
PBMC from healthy adult individuals seropositive for measles virus (MV) were tested for their capacity to proliferate to UV-inactivated MV (UV-MV) or to autologous MV-infected EBV-transformed B cell lines (EBV-BC). MV-specific T cell responses were o
Autor:
H. O. Voorma
Publikováno v:
Proceedings in Life Sciences ISBN: 9783642699146
The sequence of events in the initiation of protein synthesis in eukaryotes has been depicted for a number of years as shown in Fig. 1 (Thomas et al. 1981). The initiator Met-tRNA forms a ternary complex with eukaryotic initiation factor eIF-2 and GT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::931ec3d1118d94d63cb38ff911b01dbd
https://doi.org/10.1007/978-3-642-69912-2_10
https://doi.org/10.1007/978-3-642-69912-2_10
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 142(8)
PBMC from healthy adult individuals seropositive for measles virus (MV) were tested for their capacity to proliferate to UV-inactivated MV (UV-MV) or to autologous MV-infected EBV-transformed B cell lines (EBV-BC). MV-specific T cell responses were o
Publikováno v:
Biochemistry international. 16(3)
The interaction of GTP with initiation factor eIF-2 in different complexes was studied by affinity labeling using a derivative of [3H]GTP carrying a photoreactive group in the alpha-phosphate moiety. In the binary complex [eIF-2.GTP analogue], in the