Zobrazeno 1 - 10 of 433 pro vyhledávání: '"H O, McDevitt"'
3
CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice
Autor: B Balasa, T Krahl, G Patstone, J Lee, R Tisch, H O McDevitt, N Sarvetnick
Publikováno v: The Journal of Immunology. 159:4620-4627
The nonobese diabetic (NOD) mouse spontaneously develops T cell-dependent autoimmune diabetes. Here, we investigate the role of CD40 ligand (CD40L)-CD40 costimulation in the initiation and progression of this disease. Anti-CD40L mAb treatment of 3- t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2998c8ddd19cb102e2eeef102f4b5867
https://doi.org/10.4049/jimmunol.159.9.4620
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6
A sequential model for peptide binding and transport by the transporters associated with antigen processing
Autor: Roland Tisch, Peter van Endert, Thomas H. Meyer, Robert Tampé, Jean François Bach, H O McDevitt
Publikováno v: Immunity. 1:491-500
The TAP proteins translocate antigenic peptides into the endoplasmic reticulum. Investigation of the specificity of this process has been complicated by TAP-independent factors that influence the amount of peptide that accumulates in the ER in transp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71181bc8440b114ad4386a418a0edeb
https://doi.org/10.1016/1074-7613(94)90091-4
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8
Inhibition of experimental autoimmune encephalomyelitis by a nonimmunogenic non-self peptide that binds to I-Au
Autor: A M Gautam, C I Pearson, A A Sinha, D E Smilek, L Steinman, H O McDevitt
Publikováno v: The Journal of Immunology. 148:3049-3054
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory neurologic disease initiated by myelin basic protein-reactive CD4+ T cells, which are restricted by a particular MHC class II molecule. Recent studies have utilized inhibitor peptides
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b21c8c69b6c620d1d4c906289b3ef5d
https://doi.org/10.4049/jimmunol.148.10.3049
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9
An immune response defect due to low levels of class II cell surface expression. Analysis of antigen presentation and positive selection
Autor: S Gilfillan, S Aiso, D Smilek, D L Woodland, E Palmer, H O McDevitt
Publikováno v: The Journal of Immunology. 147:4074-4081
The effects of quantitative differences in class II cell surface expression have been difficult to address in intact animals. This study uses several lines of H-2s/s mice carrying an A beta k transgene that differ significantly in terms of class II c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f81b428b6854a0b830b152b9056d8c7
https://doi.org/10.4049/jimmunol.147.12.4074
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10
Monoclonal Anti-La Antibody Therapy in Animal Models of Autoimmune Disease
Autor: H O McDevitt, L A Steinman, R Perry
Publikováno v: Ciba Foundation Symposium 129-Autoimmunity and Autoimmune Disease
Allele-specific monoclonal anti-I-A antibodies are capable of specifically suppressing the immune response to antigens under the control of the allele towards which the antibody is directed, without suppressing the response to antigens under the cont
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84998fc82fa032fac3e5a42f6bbc5699
https://doi.org/10.1002/9780470513484.ch12
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