Zobrazeno 1 - 10
of 60
pro vyhledávání: '"H O, Garland"'
Autor:
H. Bond, K. Hamilton, R. J. Balment, J. Denton, A. J. Freemont, H. O. Garland, J. D. Glazier, C. P. Sibley
Publikováno v:
Diabetologia. 48:1393-1400
We tested the hypothesis that diabetes in pregnancy can result in the in-utero reprogramming of renal calcium and magnesium handling and of bone formation in the offspring, which persists into adulthood. Male offspring of streptozotocin-treated diabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e5ee1a4813697bc43413d0fb9116c0
https://doi.org/10.1007/s00125-005-1804-5
https://doi.org/10.1007/s00125-005-1804-5
Publikováno v:
British Journal of Pharmacology. 130:441-449
In vivo renal micropuncture techniques were used to locate the nephron site of hypercalciuria induced by acute gentamicin infusion in anaesthetized Sprague Dawley rats. Three series of experiments were conducted. The effect of gentamicin on calcium r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::299308a2f3af3f910c07636c05c302ed
https://doi.org/10.1038/sj.bjp.0703329
https://doi.org/10.1038/sj.bjp.0703329
Autor:
K Hamilton, Colin P. Sibley, E. B. Mawer, H. O. Garland, J. L. Berry, Richard J. Balment, R.D.H. Boyd, M. Tein, Jocelyn D. Glazier
Publikováno v:
Journal of Endocrinology. 164:67-76
Offspring of rats with diabetes mellitus are at risk of reduced calcium and bone mineral content. Altered expression of the maternal calcium binding proteins, calbindin-D(9K) and calbindin-D(28K), which are involved in renal and placental calcium tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0b96f9ad4eebe6dfcc0b113abaa0f9
https://doi.org/10.1677/joe.0.1640067
https://doi.org/10.1677/joe.0.1640067
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 25:231-235
1. Rats with streptozotocin (STZ) diabetes are protected from gentamicin (GEN) nephrotoxicity. Because the chronic renal damage from GEN is preceded by acute renal functional changes (notably hypercalciuria), the present study aims to determine wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77eafc0e54c97cba998c2aa3ea0f665
https://doi.org/10.1111/j.1440-1681.1998.t01-8-.x
https://doi.org/10.1111/j.1440-1681.1998.t01-8-.x
Publikováno v:
British Journal of Pharmacology. 122:570-576
1 Standard renal clearance techniques were used to assess the dose-response relationship between acute gentamicin infusion and the magnitude of hypercalciuria and hypermagnesiuria in the anaesthetized Sprague-Dawley rat. Also investigated were whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53e5f65c4e36ff85013223f7f12da4f1
https://doi.org/10.1038/sj.bjp.0701403
https://doi.org/10.1038/sj.bjp.0701403
Publikováno v:
Journal of Endocrinology. 153:357-363
Hypercalciuria may be a contributory factor to the disturbed calcium homoeostasis seen in diabetic pregnant rats and their offspring. In diabetes, essential fatty acid metabolism is impaired. We have therefore investigated whether feeding a diet supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9771d234d02ca1a5682c72addfa8fc
https://doi.org/10.1677/joe.0.1530357
https://doi.org/10.1677/joe.0.1530357
Autor:
K Hamilton, John C. Pickup, Clifford J. Bailey, G Chusney, Caroline Day, H. O. Garland, Alison Samuel, Richard J. Balment
Publikováno v:
Life Sciences. 57:1383-1391
An elevated circulating sialic acid concentration is a risk factor for cardiovascular disease. Serum sialic acid levels are elevated in NIDDM but not in uncomplicated IDDM. To study why sialic acid is increased in some types of diabetes, we assayed p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9abaff2e3f25865ba56ad99528b6808
https://doi.org/10.1016/0024-3205(95)02096-2
https://doi.org/10.1016/0024-3205(95)02096-2
Publikováno v:
Pediatric Research. 35:376-380
The effect of maternal diabetes mellitus on placental unidirectional maternofetal flux of calcium (Ca) and magnesium (Mg), calbindin9K mRNA expression, and net fetal Ca and Mg accretion has been investigated using control (C), untreated diabetic (D(O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3902b24fc112ae66a8ae4bb7a177b2d9
https://doi.org/10.1203/00006450-199403000-00022
https://doi.org/10.1203/00006450-199403000-00022
Autor:
C. G. Davidge, H. O. Garland, J. T. McLaughlin, L. M. Oakes, E. S. Harpur, T. J. Birdsey, A. J. Smith
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 21:109-115
1. Standard renal clearance techniques were used to compare the acute effects of gentamicin, neomycin and tobramycin on renal calcium and magnesium handling in Sprague-Dawley and Fischer 344 rats. 2. Significant hypercalciuric and hypermagnesiuric re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74eba70ee0406b99b92aaaf7899267e7
https://doi.org/10.1111/j.1440-1681.1994.tb02476.x
https://doi.org/10.1111/j.1440-1681.1994.tb02476.x
Publikováno v:
Journal of Endocrinology. 131:373-380
In-vivo microperfusion was used to localize the reabsorptive defect responsible for the hypercalciuria of diabetes mellitus and to investigate possible causative factors. Unidirectional proximal calcium absorption was not significantly different in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::251b7bd8fa5ee5efb948310c7fbf3260
https://doi.org/10.1677/joe.0.1310373
https://doi.org/10.1677/joe.0.1310373