Zobrazeno 1 - 4
of 4
pro vyhledávání: '"H N, Stevens"'
Publikováno v:
Pharmaceutical research. 9(5)
Captopril has been administered to eight healthy male subjects by means of a pulsatile delivery system that was designed to release the drug in the colonic region of the intestine. The gastrointestinal transit and pulsatile release were followed usin
Publikováno v:
Pharmaceutical research. 5(4)
The stability-pH profile of the gamma-aminobutyric acid prodrug. Progabide, was found to be bell shaped, with maximum stability occurring at pH 6 to 7 with a t1/2 of 126 min. Of its metabolic derivatives, the deamidated product PGA degraded in a simi
Publikováno v:
The Journal of pharmacy and pharmacology.
Publikováno v:
Pharmaceutical research. 4(1)
A reversed-phase high-performance liquid chromatography (HPLC) assay procedure for Progabide, its active acid metabolite (PGA), and its hydrolytic degradation product (SL79.182) has been developed. This highly specific technique has allowed the simul