Zobrazeno 1 - 10
of 50
pro vyhledávání: '"H N, Jayaram"'
Autor:
Sunesh Kumar Jain, Neerja Bhatla, Ayan Banerjee, H. N. Jayaram, Deepti Bajpai, Neeta Singh, Sujata Pathak
Publikováno v:
Nutrition and cancer. 66(5)
Most cases of cervical cancer are associated with human papilloma virus (HPV) infection of high risk types. In folate deficiency, heterogeneous nuclear ribonucleoprotein E1 (hnRNP-E1) interferes with HPV16 viral capsid protein synthesis. We aimed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2709c339144a03a34e7e9b5786d9150b
https://pubmed.ncbi.nlm.nih.gov/24848140
https://pubmed.ncbi.nlm.nih.gov/24848140
Publikováno v:
Current Medicinal Chemistry. 6:629-634
Abstracts: Mycophenolic acid (MPA) is the most potent and specific inhibitor of inosine monophosphate dehydrogenase (IMPDH). This compound was reported to bind the NAD site of IMPDH and mimic the binding of nicotinamide moiety of nicotinamide adenine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3294a60c77938c77b0b5b0cc83942bc
https://doi.org/10.2174/092986730607220401124820
https://doi.org/10.2174/092986730607220401124820
Autor:
G. Perra, T. Sint, G. Abu Sheikha, S. Poma, Mario Grifantini, Barry M. Goldstein, Loredana Cappellacci, Palmarisa Franchetti, P. La Colla, H. N. Jayaram, Bryan P. Schneider, V. V. Gurudutt
Publikováno v:
Nucleosides and Nucleotides. 16:1045-1048
The synthesis of 5-β-D-ribofuranosylselenophene-3-carboxamide (selenophenfurin) is reported. Selenophenfurin was found active as cytotoxic agent and as inosine monophosphate dehydrogenase inhibitor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7fa8ada3802be426c9f98dca43128de
https://doi.org/10.1080/07328319708006129
https://doi.org/10.1080/07328319708006129
Autor:
Barry M. Goldstein, H. Yang, A. Barzi, H. N. Jayaram, C. Carrell, Giuseppe Nocentini, Mario Grifantini, Palmarisa Franchetti, A. Oconnor, Loredana Cappellacci
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c897e55f59a617d1f958b8bc1710737d
https://doi.org/10.1002/chin.199603242
https://doi.org/10.1002/chin.199603242
Autor:
Loredana Cappellacci, V. V. Gurudutt, A. G. Loi, Ghassan Abu Sheikha, Mario Grifantini, A. De Montis, Bryan P. Schneider, T. Sint, H. N. Jayaram, William D. Jones, P. La Colla, Graziella Perra, Barry M. Goldstein, Palmarisa Franchetti
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3021c1aab4904b0d8b6dfde8738050ee
https://doi.org/10.1002/chin.199739258
https://doi.org/10.1002/chin.199739258
Autor:
Loredana Cappellacci, Palmarisa Franchetti, F. R. Collart, Eliezer Huberman, Bryan P. Schneider, V. V. Gurudutt, T. Sint, Ghassan Abu Sheikha, H. N. Jayaram, Mario Grifantini
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2886e6c9dcdff9b645d8ad16337bb373
https://doi.org/10.1002/chin.199812206
https://doi.org/10.1002/chin.199812206
Publikováno v:
Biochemical Pharmacology. 41:281-286
Tiazofurin is an oncolytic agent which has shown therapeutic activity in end-stage acute nonlymphocytic leukemia (ANLL) and blast crisis of chronic granulocytic leukemia (CGL-BC). Tiazofurin is anabolized to the active metabolite, thiazole-4-carboxam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a529987e53538ee7e2721d7d1dde9158
https://doi.org/10.1016/0006-2952(91)90487-p
https://doi.org/10.1016/0006-2952(91)90487-p
Publikováno v:
Life sciences. 75(2)
Benzamide riboside (BR) is a novel anticancer agent exhibiting pronounced activity against several human tumor cell lines via the inhibition of inosine 5'-monophosphate dehydrogenase (IMPDH), thereby restricting the biosynthesis of guanylates. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b1736f4b47bef64674dd1c848102f8
https://pubmed.ncbi.nlm.nih.gov/15120570
https://pubmed.ncbi.nlm.nih.gov/15120570
Publikováno v:
ACS Symposium Series ISBN: 9780841237803
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60d697b3c0ac92b0e65a3031bf0988c
http://hdl.handle.net/11581/113610
http://hdl.handle.net/11581/113610
Autor:
P, Franchetti, S, Marchetti, L, Cappellacci, J A, Yalowitz, H N, Jayaram, B M, Goldstein, M, Grifantini
Publikováno v:
Bioorganicmedicinal chemistry letters. 11(1)
2-Beta-D-ribofuranosylimidazole-4-carboxamide, an imidazole analogue of the antitumor agent tiazofurin, was synthesized and evaluated for the growth inhibitory activity of human myelogenous leukemia K562 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bef83bf48d5b1535d6e6a1eb5f3b6fe7
https://pubmed.ncbi.nlm.nih.gov/11140736
https://pubmed.ncbi.nlm.nih.gov/11140736