Zobrazeno 1 - 10
of 2 509
pro vyhledávání: '"H Mody"'
Autor:
Elaine Dumoulin, Christina S. Thornton, John H. MacGregor, Alain Tremblay, Chrystal Chan, Paul R. MacEachern, Margaret M. Kelly, Ranjani Somayaji, Michael D. Parkins, Christopher H. Mody
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 18 (2024)
Intracavitary pulmonary aspergilloma is a persistent and life-threatening infection that carries a mortality rate of up to 15%. It occurs when Aspergillus species gain entry to an existing lung cavity. In the absence of definitive treatment, patients
Externí odkaz:
https://doaj.org/article/614f2fb9929e449fb7ebd6d581be6ac7
Publikováno v:
Asian Journal of Transfusion Science, Vol 15, Iss 2, Pp 189-194 (2021)
BACKGROUND AND OBJECTIVES: Platelet concentrates (PCs) can be prepared in several different ways, and they can be stored over few days before the use. Regulated on activation, normal T cells expressed and secreted (RANTES) levels in these concentrate
Externí odkaz:
https://doaj.org/article/6d60bfd91ec94807a010eeaa8b6994dc
Autor:
David D Feehan, Khusraw Jamil, Maria J Polyak, Henry Ogbomo, Mark Hasell, Shu Shun Li, Richard F Xiang, Michael Parkins, Joseph A Trapani, Joe J Harrison, Christopher H Mody
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010325 (2022)
Pseudomonas aeruginosa is an opportunistic pathogen that often infects individuals with the genetic disease cystic fibrosis, and contributes to airway blockage and loss of lung function. Natural killer (NK) cells are cytotoxic, granular lymphocytes t
Externí odkaz:
https://doaj.org/article/b778c7014af347808053473fb513adcf
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting side effect that occurs in up to 63% of patients and has no known effective treatment. A majority of studies do not effectively assess sex differences in the onset and persist
Externí odkaz:
https://doaj.org/article/a19a1e7f1c004208a6ec6d5839579696
Autor:
Khusraw Jamil, Maria J. Polyak, David D. Feehan, Philip Surmanowicz, Danuta Stack, Shu Shun Li, Henry Ogbomo, Michal Olszewski, Anutosh Ganguly, Christopher H. Mody
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Cryptococcus gattii is a major cause of life-threatening mycosis in immunocompetent individuals and responsible for the ongoing epidemic outbreak of cryptococcosis in the Pacific Northwest of North America. This deadly fungus is known to eva
Externí odkaz:
https://doaj.org/article/92baed861cf74c3389130aba7d91830a
Autor:
Henry Ogbomo, Martina Timm-McCann, Tavish Barnes, Richard F. Xiang, Khusraw Jamil, Anutosh Ganguly, Danuta Stack, Shaunna M. Huston, Shu Shun Li, Pina Colarusso, Christopher H. Mody
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 3017-3032 (2018)
Summary: Cryptococcus is the most important cause of fungal meningitis in immunocompromised individuals. Host defense against Cryptococcus involves direct killing by NK cells. That NK cells from HIV-infected patients fail to polarize perforin to the
Externí odkaz:
https://doaj.org/article/ca9f21426ae948e5b6e639613c33ec38
Autor:
Sachin R. Pendharkar, Maria B. Ospina, Danielle A. Southern, Naushad Hirani, Jim Graham, Peter Faris, Mohit Bhutani, Richard Leigh, Christopher H. Mody, Michael K. Stickland
Publikováno v:
BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Variation in hospital management of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) may prolong length of stay, increasing the risk of hospital-acquired complications and worsening quality of lif
Externí odkaz:
https://doaj.org/article/167abe10156448c9bdc8898b68c61297
Autor:
Shu Shun Li, Henry Ogbomo, Michael K. Mansour, Richard F. Xiang, Lian Szabo, Fay Munro, Priyanka Mukherjee, Roy A. Mariuzza, Matthias Amrein, Jatin M. Vyas, Stephen M. Robbins, Christopher H. Mody
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Natural killer (NK) cells has been show to mediate fungi killing via the activating receptor NKp30, but the fungal target for NKp30 is still unclear. Here the authors show, using atomic force microscopy and live cell imaging, that β-1,3-glucan is ex
Externí odkaz:
https://doaj.org/article/2544882c0af34f56b6d9c66dfded2082
Autor:
Alexandra K. Mossman, Julianna Svishchuk, Barbara Jean M. Waddell, Conrad S. Izydorczyk, Peter T. Buckley, Jamese J. Hilliard, Gabriel Al-Ghalith, Lingjie Zheng, Anthony S. Lynch, Christopher H. Mody, Luiz F. Lisboa, Daniel B. Gregson, Michael D. Parkins
Publikováno v:
Annals of the American Thoracic Society. 19:1285-1293
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b2b23fa25ec0e834441e7d94524e19d
https://doi.org/10.1513/annalsats.202108-965oc
https://doi.org/10.1513/annalsats.202108-965oc
Publikováno v:
Journal of Fungi, Vol 7, Iss 6, p 484 (2021)
Humans have developed complex immune systems that defend against invading microbes, including fungal pathogens. Many highly specialized cells of the immune system share the ability to store antimicrobial compounds in membrane bound organelles that ca
Externí odkaz:
https://doaj.org/article/7f380957b9204864aaf36567f09358ad