Assessment of left ventricular mechanics in right ventricular overload using in silico rat models

Autor: H Martinez-Navarro, E K S Espe, O O Odeigah, I Sjaastad, J Sundnes

Publikováno v: European Heart Journal - Digital Health. 2

Background To preserve cardiac function in overload conditions, the RV adapts by developing muscular hypertrophy through progressive tissue remodelling. This process may lead to a vicious cycle with detrimental effects on RV diastolic and systolic fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d250d42555b95c6ca993892effa2256d
https://doi.org/10.1093/ehjdh/ztab104.3074

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Cardiac conduction system regeneration prevents arrhythmias after myocardial infarction.

Autor: Sayers JR; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Martinez-Navarro H; Department of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, UK., Sun X; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., de Villiers C; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Sigal S; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Weinberger M; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Rodriguez CC; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Riebel LL; Department of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, UK., Berg LA; Department of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, UK., Camps J; Department of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, UK., Herring N; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Rodriguez B; Department of Computer Science, British Heart Foundation Centre of Research Excellence, University of Oxford, Oxford, UK., Sauka-Spengler T; Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Stowers Institute for Medical Research, Kansas City, MO, USA., Riley PR; Institute of Developmental and Regenerative Medicine, University of Oxford, Oxford, UK. paul.riley@idrm.ox.ac.uk.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. paul.riley@idrm.ox.ac.uk.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2025 Jan 03. Date of Electronic Publication: 2025 Jan 03.