Výsledky vyhledávání - "H M Vordermeier"

The expression of Indoleamine 2, 3-dioxygenase (IDO) is reduced in granulomas from BCG vaccinated cattle compared to granulomas from unvaccinated controls after experimental challenge with Mycobacterium bovis

Autor: Waldo L. García-Jiménez, Duncan Grainger, Francisco J. Salguero, H. M. Vordermeier, Bernardo Villarreal-Ramos, R. Glyn Hewisnon

Publikováno v: Veterinary immunology and immunopathology. 203

Bovine tuberculosis (bTB), mainly caused by Mycobacterium bovis (M. bovis), is a major economic disease of livestock worldwide. Vaccination is considered as a potentially sustainable adjunct to the current control strategy. Cattle vaccination with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93cb9e7008c2d1b0bfb792811969e06d
https://pubmed.ncbi.nlm.nih.gov/30243373

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Vaccination of calves with Mycobacterium bovis Bacillus Calmette-Guerin reduces the frequency and severity of lesions of bovine tuberculosis under a natural transmission setting in Ethiopia

Autor: Tsegaye Hailu, A. Zewde, Gobena Ameni, M. Tilahun, Francisco J. Salguero, Stefan Berg, Asegedech Sirak, Abraham Aseffa, Tadesse Eguale, R. G. Hewinson, K. Tafess, H. M. Vordermeier

Publikováno v: Transboundary and Emerging Diseases

Summary Bovine tuberculosis (bTB) is highly prevalent in intensive dairy farms of the urban “milk‐sheds” in Ethiopia, and vaccination could be a cost‐effective disease control strategy. In the present study, the efficacy of Bacillus Calmette�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2336e570a2a6d17e6f57f613c40d4e
https://pubmed.ncbi.nlm.nih.gov/28168855

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Differential Cell Composition and Cytokine Expression Within Lymph Node Granulomas from BCG-Vaccinated and Non-vaccinated Cattle Experimentally Infected with Mycobacterium bovis

Autor: Waldo L. García-Jiménez, Tony S Strickland, S Gibson, Francisco J. Salguero, Bernardo Villarreal-Ramos, H. M. Vordermeier, J Gough

Publikováno v: Transboundary and emerging diseases. 64(6)

Cattle vaccination against bovine tuberculosis (bTB) has been proposed as a supplementary method to help control the incidences of this disease. Bacillus Calmette-Guérin (BCG) is currently the only viable candidate vaccine for immunisation of cattle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e1c3617c61e60725a58e2a1392636a
https://pubmed.ncbi.nlm.nih.gov/27615603

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Lack of correlation between BCG-induced tuberculin skin test sensitisation and protective immunity in cattle

Autor: Michael Coad, Derek Clifford, H. M. Vordermeier, B.L. Upadhyay, Adam O. Whelan, R. G. Hewinson

Publikováno v: Vaccine. 29:5453-5458

Vaccination of cattle with Mycobacterium bovis Bacille Calmette-Guérin (BCG) can provide significant protection against bovine tuberculosis (TB). However, BCG vaccination sensitises animals to respond to the tuberculin skin-test. This provides a pot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e18216a4c61c4b847c83c0b53f0c89
https://doi.org/10.1016/j.vaccine.2011.05.057

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Identification of Surrogates and Correlates of Protection in Protective Immunity against Mycobacterium bovis Infection Induced in Neonatal Calves by Vaccination with M. bovis BCG Pasteur and M. bovis BCG Danish

Autor: Derek Clifford, M. McAulay, M.L. Thom, R. G. Hewinson, H. M. Vordermeier, E. Mead, Jayne Hope, Bernardo Villarreal-Ramos

Publikováno v: Clinical and Vaccine Immunology. 18:373-379

Vaccination of neonatal calves with Mycobacterium bovis bacillus Calmette-Guérin (BCG) induces a significant degree of protection against infection with virulent M. bovis , the causative agent of bovine tuberculosis (bTB). We compared two strains o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::24f038e27b51ce112c8a8c09641652a5
https://doi.org/10.1128/cvi.00543-10

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Simultaneous Measurement of Antigen-Stimulated Interleukin-1β and Gamma Interferon Production Enhances Test Sensitivity for the Detection of Mycobacterium bovis Infection in Cattle

Autor: R. G. Hewinson, Chris Pirson, Gareth Jones, H. M. Vordermeier

Publikováno v: Clinical and Vaccine Immunology. 17:1946-1951

In order to identify cytokines that may be useful as candidates for inclusion in diagnostic tests for Mycobacterium bovis infection in cattle, we compared the levels of gamma interferon (IFN-γ), interleukin 1β (IL-1β), IL-4, IL-10, IL-12, macropha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201b70353e9b1387a467f0bec2940ca3
https://doi.org/10.1128/cvi.00377-10

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Adjuvants Induce Distinct Immunological Phenotypes in a Bovine Tuberculosis Vaccine Model

Autor: Philip J. Hogarth, G. S. Dean, Ida Rosenkrands, R. G. Hewinson, H. M. Vordermeier, Else Marie Agger, Peter Andersen, Daryan A. Kaveh

Publikováno v: ResearcherID

Tuberculosis (TB) remains one of the most important infectious diseases of humans and animals. Mycobacterium bovis BCG, the only currently available TB vaccine, demonstrates variable levels of efficacy; therefore, a replacement or supplement to BCG i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc6507095822d695d8a6b6268e36c48
https://doi.org/10.1128/cvi.00229-09

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Assessment of Mycobacterium tuberculosis OmpATb as a Novel Antigen for the Diagnosis of Bovine Tuberculosis

Autor: W. R. Waters, Tyler C. Thacker, Bruno Oesch, Irene Schiller, Beatrice Marg-Haufe, Alex Raeber, Adam O. Whelan, Mitchell V. Palmer, R. Hardegger, H. M. Vordermeier

Publikováno v: Clinical and Vaccine Immunology. 16:1314-1321

In the search for better tools to control bovine tuberculosis, the development of diagnostic tests with improved specificity and sensitivity has a high priority. We chose to search for novel immunodiagnostic reagents. In this study, Rv0899 (outer mem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2d7b7a249204d2fc9cd70807f6cf38
https://doi.org/10.1128/cvi.00151-09

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Isoniazid treatment of Mycobacterium bovis in cattle as a model for human tuberculosis

Autor: E. Mead, Paul R. Wheeler, B. Villareal-Ramos, H. M. Vordermeier, Shelley G. Rhodes, Linda K. Johnson, Derek Clifford, Adam O. Whelan, Michael Coad, R. G. Hewinson, G. S. Dean

Publikováno v: Tuberculosis. 88:586-594

Cattle infected with Mycobacterium bovis spoligotype 9 were treated with Isoniazid (INH) from three to 14 weeks post infection, rested for fourweeks to allow INH depletion and then challenged with M. bovis spoligotype 35. Post mortem examination (PME

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f6705fee23199ed0b379e8a71bfb18
https://doi.org/10.1016/j.tube.2008.01.004

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The effect of tuberculin testing on the development of cell-mediated immune responses during Mycobacterium bovis infection

Autor: Jayne Hope, H. M. Vordermeier, Tracey J. Coffey, S.A. Stephens, M.L. Thom, M. McAulay, Chris J. Howard, Bernardo Villarreal-Ramos

Publikováno v: Veterinary Immunology and Immunopathology. 114:25-36

Protection against tuberculosis (TB) is associated with Th1-type cell-mediated immunity (CMI). Whilst the intradermal injection of partially purified derivatives of tuberculin (PPD) represents the classic test assessing the delayed type hypersensitiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3cdd3d8fb300f59e9a611ad47a48bd6
https://doi.org/10.1016/j.vetimm.2006.07.001

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