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This article is a revision of the previous edition article by Sharmilee P. Sawant and Harihara M. Mehendale, volume 1, pp 206–207, © 2005, Elsevier Inc.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459e409a01e1808f26cb0eabebf6c2ec
https://doi.org/10.1016/b978-0-12-386454-3.00244-x
https://doi.org/10.1016/b978-0-12-386454-3.00244-x
Publikováno v:
Hepatology. 26:1250-1257
The mechanisms of liver injury from cold storage and reperfusion are not completely understood. The aim of the present study was to investigate: 1) whether the inactivation of Kupffer cells (KCs) by gadolinium chloride (GadCl) modulates cold ischemia
Publikováno v:
Medical Hypotheses. 46:261-268
Survival after hepatocellular injury and necrosis may depend on the ability of the remaining hepatocytes to divide and restore an adequate population of functioning cells. Although adequate nutritional support is necessary for liver regeneration afte
Autor:
M. G. SONI, H. M. MEHENDALE
Publikováno v:
Toxicological Sciences. 21:442-450
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 29(8)
Earlier studies have shown highly exaggerated mechanism-based liver injury of thioacetamide (TA) in rats following moderate diet restriction (DR) and in diabetes. The objective of the present study was to investigate the mechanism of higher liver inj
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(2)
Thioacetamide (TA)-induced hepatotoxicity is potentiated in streptozotocin (STZ)-induced diabetic rats. The relative roles of CYP2E1 and FMO1 in the mechanism of TA-associated liver injury were investigated. In the STZ-induced diabetic rat, hepatic C
Autor:
M G Soni, H M Mehendale
Publikováno v:
Environmental Health Perspectives
It is widely recognized that exposure to combinations or mixtures of chemicals may result in highly exaggerated toxicity even though individual chemicals might not be toxic at low doses. Chemical mixtures may also cause additive or less than additive
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 45(2)
Although, diet restriction (DR) has been shown to substantially increase longevity while reducing or delaying the onset of age-related diseases, little is known about the mechanisms underlying the beneficial effects of DR on acute toxic outcomes. An
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 42(2)
Trichloroethylene (TCE), a widely used organic solvent and degreasing agent, is regarded as a hepatotoxicant. The objective of the present studies was to investigate whether the extent and timeliness of tissue repair has a determining influence on th
Publikováno v:
Archives of toxicology. 70(11)
Fischer 344 (F344) rats are reportedly 75-fold more sensitive than Sprague Dawley (S-D) rats to 1,2-dichlorobenzene (o-DCB) hepatotoxicity. Lethality studies were conducted since no information was available regarding the ultimate consequence of this