The EU chemicals strategy for sustainability: in support of the BfR position

Autor: H. M. Bolt, Helmut Greim, Christopher J. Borgert, Daniel R. Dietrich, Emanuela Testai, Pat Heslop-Harrison, Hans Marquardt, Alan R. Boobis, Olavi Pelkonen, Bas J. Blaauboer, Angela Mally, Gio Batta Gori, Sam Kacew, Corrado L. Galli, Jan G. Hengstler, José L. Domingo, Wolfgang Dekant, Kai Savolainen, Nico P. E. Vermeulen, Sir Colin Berry, Frank A. Barile, Aristides M. Tsatsakis

Publikováno v: Barile, F A, Berry, S C, Blaauboer, B, Boobis, A, Bolt, H M, Borgert, C, Dekant, W, Dietrich, D, Domingo, J L, Galli, C L, Gori, G B, Greim, H, Hengstler, J G, Heslop-Harrison, P, Kacew, S, Marquardt, H, Mally, A, Pelkonen, O, Savolainen, K, Testai, E, Tsatsakis, A & Vermeulen, N P 2021, ' The EU chemicals strategy for sustainability: in support of the BfR position ', Archives of Toxicology, vol. 95, no. 9, pp. 3133-3136 . https://doi.org/10.1007/s00204-021-03125-w
Archives of Toxicology, 95(9), 3133-3136. Springer Verlag
Archives of Toxicology

The EU chemicals strategy for sustainability (CSS) asserts that both human health and the environment are presently threatened and that further regulation is necessary. In a recent Guest Editorial, members of the German competent authority for risk a

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https://doi.org/10.1007/s00204-021-03125-w

Critique of the 'Comment' etitled 'Pyrethroid exposure: Not so harmless after all' by Demeneix et al. (2020) published in the lancet diabetes endocrinology

Autor: Gio Batta Gori, H. M. Bolt, Olavi Pelkonen, Alan R. Boobis, Helmut Greim, Wolfgang Dekant, Bas J. Blaauboer, José L. Domingo, Hans Marquardt, Jan G. Hengstler, Sam Kacew, Daniel R. Dietrich, Pat Heslop-Harrison, Sir Colin Berry, Kai Savolainen, Frank A. Barile, Nico P. E. Vermeulen, Aristides M. Tsatsakis, Christopher J. Borgert

Publikováno v: Toxicology Letters, 340, 1-3. Elsevier BV
Barile, F A, Berry, S C, Blaauboer, B, Boobis, A, Bolt, H, Borgert, C J, Dekant, W, Dietrich, D, Domingo, J L, Gori, G B, Greim, H, Hengstler, J, Kacew, S, Marquardt, H, Pelkonen, O, Savolainen, K, Heslop-Harrison, P, Tsatsakis, A & Vermeulen, N P 2021, ' Critique of the “Comment” etitled “Pyrethroid exposure: Not so harmless after all” by Demeneix et al. (2020) published in the lancet diabetes endocrinology ', Toxicology Letters, vol. 340, pp. 1-3 . https://doi.org/10.1016/j.toxlet.2020.12.020

The authors regret that the letter inaccurately refers to “the lancet diabetes endocrinology” and “The Lancet” while it should read: “The Lancet Diabetes & Endocrinology”. The correct title of the letter should read: “Critique of the �

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https://research.vu.nl/en/publications/10ef17b1-78ab-432e-864d-a3e12098fa80

Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs?

Autor: Olavi Pelkonen, Daniel R. Dietrich, Herman Autrup, H. M. Bolt, Sir Colin Berry, Bas J. Blaauboer, Frank A. Barile, Wolfgang Dekant, Gio Batta Gori, José L. Domingo, Christopher J. Borgert, Pat Heslop-Harrison, Jan G. Hengstler, Alan R. Boobis, Hans Marquardt, Sam Kacew, Helmut Greim, Kai Savolainen, Nico P. E. Vermeulen

Publikováno v: Toxicology in Vitro, 67:104861, 1-6. Elsevier Limited
Autrup, H, Barile, F A, Colin Berry, S, Blaauboer, B J, Boobis, A, Bolt, H, Borgert, C J, Dekant, W, Dietrich, D, Domingo, J L, Batta Gori, G, Greim, H, Hengstler, J, Kacew, S, Marquardt, H, Pelkonen, O, Savolainen, K, Heslop-Harrison, P & Vermeulen, N P 2020, ' Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs? ', Computational Toxicology, vol. 14, 100124, pp. 1-6 . https://doi.org/10.1016/j.comtox.2020.100124
Autrup, H, Barile, F A, Berry, S C, Blaauboer, B J, Boobis, A, Bolt, H, Borgert, C J, Dekant, W, Dietrich, D, Domingo, J L, Gori, G B, Greim, H, Hengstler, J, Kacew, S, Marquardt, H, Pelkonen, O, Savolainen, K, Heslop-Harrison, P & Vermeulen, N P 2020, ' Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs? ', Journal of Toxicology and Environmental Health, Part A, vol. 83, no. 13-14, pp. 485-494 . https://doi.org/10.1080/15287394.2020.1756592
Autrup, H, Barile, F A, Berry, S C, Blaauboer, B J, Boobis, A, Bolt, H, Borgert, C J, Dekant, W, Dietrich, D, Domingo, J L, Gori, G B, Greim, H, Hengstler, J, Kacew, S, Marquardt, H, Pelkonen, O, Savolainen, K, Heslop-Harrison, P & Vermeulen, N P 2020, ' Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity : how to evaluate the risk of the S-EDCs? ', Archives of Toxicology, vol. 94, no. 7, pp. 2549-2557 . https://doi.org/10.1007/s00204-020-02800-8
Toxicology Letters, 331, 259-264. Elsevier BV
Autrup, H, Barile, F A, Berry, S C, Blaauboer, B J, Boobis, A, Bolt, H, Borgert, C J, Dekant, W, Dietrich, D, Domingo, J L, Gori, G B, Greim, H, Hengstler, J, Kacew, S, Marquardt, H, Pelkonen, O, Savolainen, K, Heslop-Harrison, P & Vermeulen, N P 2020, ' Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs? ', Environmental Toxicology and Pharmacology, vol. 78, 103396, pp. 1-6 . https://doi.org/10.1016/j.etap.2020.103396
Archives of Toxicology
Autrup, H, Barile, F A, Berry, S C, Blaauboer, B J, Boobis, A, Bolt, H, Borgert, C J, Dekant, W, Dietrich, D, Domingo, J L, Gori, G B, Greim, H, Hengstler, J, Kacew, S, Marquardt, H, Pelkonen, O, Savolainen, K, Heslop-Harrison, P & Vermeulen, N P 2020, ' Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity : How to evaluate the risk of the S-EDCs? ', Chemico-Biological Interactions, vol. 326, 109099, pp. 1-6 . https://doi.org/10.1016/j.cbi.2020.109099
Archives of toxicology, 94:2549-2557
Journal of Toxicology and Environmental Health, Part A, 83(13-14), 485-494. Taylor and Francis Ltd.
Archives of Toxicology, 94(7), 2549-2557. Springer Verlag
Chemico-Biological Interactions, 326:109099, 1-6. Elsevier Ireland Ltd
Autrup, H, Barile, F A, Berry, S C, Blaauboer, B J, Boobis, A, Bolt, H, Borgert, C J, Dekant, W, Dietrich, D, Domingo, J L, Gori, G B, Greim, H, Hengstler, J, Kacew, S, Marquardt, H, Pelkonen, O, Savolainen, K, Heslop-Harrison, P & Vermeulen, N P 2020, ' Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs? ', Environmental Toxicology and Pharmacology, vol. 78, 103396 . https://doi.org/10.1016/j.etap.2020.103396
Environmental Toxicology and Pharmacology, 78:103396, 1-6. Elsevier
Autrup, H, Barile, F A, Berry, S C, Blaauboer, B J, Boobis, A, Bolt, H, Borgert, C J, Dekant, W, Dietrich, D, Domingo, J L, Gori, G B, Greim, H, Hengstler, J, Kacew, S, Marquardt, H, Pelkonen, O, Savolainen, K, Heslop-Harrison, P & Vermeulen, N P 2020, ' Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs? ', Toxicology in Vitro, vol. 67, 104861, pp. 1-6 . https://doi.org/10.1016/j.tiv.2020.104861
Computational Toxicology, 14:100124, 1-6. Elsevier
Autrup, H, Barile, F A, Berry, S C, Blaauboer, B J, Boobis, A, Bolt, H, Borgert, C J, Dekant, W, Dietrich, D, Domingo, J L, Gori, G B, Greim, H, Hengstler, J, Kacew, S, Marquardt, H, Pelkonen, O, Savolainen, K, Heslop-Harrison, P & Vermeulen, N P 2020, ' Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs? ', Toxicology Letters, vol. 331, pp. 259-264 . https://doi.org/10.1016/j.toxlet.2020.04.008

Theoretically, both synthetic endocrine disrupting chemicals (S-EDCs) and natural (exogenous and endogenous) endocrine disrupting chemicals (N-EDCs) can interact with endocrine receptors and disturb hormonal balance. However, compared to endogenous h

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https://doi.org/10.1016/j.comtox.2020.100124

Highlight report: Occupational urinary bladder cancer

Autor: H M, Bolt

Publikováno v: EXCLI Journal

EXCLI Journal; 16:Doc1319; ISSN 1611-2156

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The cytoprotective and the dark side of Nrf2

Autor: H. M. Bolt, Rosemarie Marchan

Publikováno v: Archives of Toxicology. 87:2047-2050

where it induces transcription of a number of cytoprotec-tive genes.In their comprehensive review, Baird and Dinkova-Kostova (2011) present different models of regulation, such as the ‘sequester and release model’ for Keap1-Nrf2, the role of cull

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https://doi.org/10.1007/s00204-013-1165-7