Zobrazeno 1 - 5
of 5
pro vyhledávání: '"H M, Scherch"'
Autor:
E D, Hall, P K, Andrus, S L, Smith, T J, Fleck, H M, Scherch, B S, Lutzke, G A, Sawada, J S, Althaus, P F, Vonvoigtlander, G E, Padbury, P G, Larson, J R, Palmer, G L, Bundy
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(2)
A novel group of antioxidant compounds, the pyrrolopyrimidines, has been discovered recently. Many of these possess significantly improved oral bioavailability (56-70% in rats), increased efficacy and potency in protecting cultured neurons against ir
Autor:
E D, Hall, P K, Andrus, S L, Smith, J A, Oostveen, H M, Scherch, B S, Lutzke, T J, Raub, G A, Sawada, J R, Palmer, L S, Banitt, J S, Tustin, K L, Belonga, D E, Ayer, G L, Bundy
Publikováno v:
Acta neurochirurgica. Supplement. 66
The 21-aminosteroid (lazaroid) tirilazad mesylate has been demonstrated to be a potent inhibitor of lipid peroxidation and to reduce traumatic and ischemic damage in a number of experimental models. Currently, tirilazad is being actively investigated
Publikováno v:
Research communications in chemical pathology and pharmacology. 83(3)
Nitric oxide (NO) is made by NO synthase during the conversion of arginine to citrulline. Researchers have found that they can block the actions of excitotoxins by inhibiting NO synthase. Released from excitable cells during trauma, NO may react with
Autor:
E D, Hall, J M, Braughler, P A, Yonkers, S L, Smith, K L, Linseman, E D, Means, H M, Scherch, P F, Von Voigtlander, R A, Lahti, E J, Jacobsen
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 258(2)
U-78517F (2-[4-[2,6-di-(1-pyrrolidinyl)-4-pyridinyl)-1-piperazinyl] methyl]-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol, dihydrochloride), which combines the antioxidant ring portion of alpha-tocopherol together with the amine of the previou
Publikováno v:
Annals of the New York Academy of Sciences. 553:588-589