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Lipolytic action of cholera toxin on fat cells. Re-examination of the concept implicating GM1 ganglioside as the native membrane receptor

Autor: T P Carter, J N Kanfer, H M Katzen

Publikováno v: Journal of Biological Chemistry. 251:7610-7619

The possible role of galactosyl-N-acetylgalactosaminyl-[N-acetylneuraminyl]-galactosylglucosylceramide (GM1) ganglioside in the lipolytic activity of cholera toxin on isolated fat cells has been examined. Analyses of the ganglioside content and compo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4be44f569cdfc7ab465c2aefc177d462
https://doi.org/10.1016/s0021-9258(17)32895-8

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Carbohydrate inhibitors of concanavalin A that inhibit binding of insulin-sepharose to fat cells and antagonize and mimic insulin's bioactivity. A possible role for membrane carbohydrate in insulin's action

Autor: H M, Katzen

Publikováno v: The Journal of biological chemistry. 254(8)

A consistent pattern of insulin-like properties is expressed by a variety of glycoside inhibitors of concanavalin A (Con A), and is suggestive of a common mechanism of action to explain these effects. Various exogenously added glycoside derivatives i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::037d1b5450c4d1d4d7657ddc96511a8d
https://pubmed.ncbi.nlm.nih.gov/429330

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The effects of somatostatin and selected analogs on lipid absorption in animals

Autor: E E, Slater, H M, Katzen, R F, Nutt, R, Saperstein, S L, Steelman

Publikováno v: Advances in experimental medicine and biology. 188

Based upon the clinical finding that a Merck somatostatin-14 (S-14) analog induced steatorrhea in man, we sought to develop animal models to study the effects of S-14 and a series of synthetic analogs on absorption. Rats were trained to eat a diet (p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::684026fee400262918ff4e2157aa9b1a
https://pubmed.ncbi.nlm.nih.gov/2863942

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Lipolytic action of cholera toxin on fat cells. Re-examination of the concept implicating GM1 ganglioside as the native membrane receptor

Autor: J N, Kanfer, T P, Carter, H M, Katzen

Publikováno v: The Journal of biological chemistry. 251(23)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1b18a5ea1b5afae571e18ca2d8a7e843
https://pubmed.ncbi.nlm.nih.gov/1002701

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