Zobrazeno 1 - 10
of 303
pro vyhledávání: '"H Lee, Sweeney"'
Autor:
Rebecca J. Willcocks, Alison M. Barnard, Michael J. Daniels, Sean C. Forbes, William T. Triplett, John F. Brandsema, Erika L. Finanger, William D. Rooney, Sarah Kim, Dah‐Jyuu Wang, Donovan J. Lott, Claudia R. Senesac, Glenn A. Walter, H. Lee Sweeney, Krista Vandenborne
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 1, Pp 67-78 (2024)
Abstract Objective Magnetic resonance (MR) measures of muscle quality are highly sensitive to disease progression and predictive of meaningful functional milestones in Duchenne muscular dystrophy (DMD). This investigation aimed to establish the repro
Externí odkaz:
https://doaj.org/article/4a848dd8b4bb4a98b68cbbe201dd5627
Autor:
Louise Canon, Carlos Kikuti, Vicente J. Planelles-Herrero, Tianming Lin, Franck Mayeux, Helena Sirkia, Young il Lee, Leila Heidsieck, Léonid Velikovsky, Amandine David, Xiaoyan Liu, Dihia Moussaoui, Emma Forest, Peter Höök, Karl J. Petersen, Tomos E. Morgan, Aurélie Di Cicco, Julia Sirés-Campos, Emmanuel Derivery, Daniel Lévy, Cédric Delevoye, H. Lee Sweeney, Anne Houdusse
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Myosin VI (Myo6) is the only minus-end directed nanomotor on actin, allowing it to uniquely contribute to numerous cellular functions. As for other nanomotors, the proper functioning of Myo6 relies on precise spatiotemporal control of motor
Externí odkaz:
https://doaj.org/article/9c1a197ee24d4bfc8261601e8244d9ad
Publikováno v:
Cells, Vol 13, Iss 14, p 1168 (2024)
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease caused by mutations to the dystrophin gene, resulting in deficiency of dystrophin protein, loss of myofiber integrity in skeletal and cardiac muscle, and eventual cell death and
Externí odkaz:
https://doaj.org/article/3052f6ea53aa4bc48939dd60b4ae7440
Autor:
Sandra Zampieri, Ines Bersch, Piera Smeriglio, Elena Barbieri, Massimo Ganassi, Christiaan Leeuwenburg, Riccardo Rosati, Paolo Gargiulo, Amber Pond, H. Lee Sweeney, Ugo Carraro
Publikováno v:
European Journal of Translational Myology (2023)
At the end of the 2023 Padua Days of Muscle and Mobility Medicine the next year's meeting was scheduled from 27 February to 2 March 2024 (2024Pdm3). During the summer and autumn the program was confirmed with Scientific Sessions that will take place
Externí odkaz:
https://doaj.org/article/ad5d23ccd4a04c318690fd64cfc4e885
Autor:
Daria Neyroud, Orlando Laitano, Aneesha Dasgupta, Christopher Lopez, Rebecca E. Schmitt, Jessica Z. Schneider, David W. Hammers, H. Lee Sweeney, Glenn A. Walter, Jason Doles, Sarah M. Judge, Andrew R. Judge
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Cancer-induced muscle wasting reduces quality of life, complicates or precludes cancer treatments, and predicts early mortality. Herein, we investigate the requirement of the muscle-specific E3 ubiquitin ligase, MuRF1, for muscle wasting ind
Externí odkaz:
https://doaj.org/article/325bfe808b054fee84c0ec177166dbea
Autor:
Alan J. Russell, Mike DuVall, Ben Barthel, Ying Qian, Angela K. Peter, Breanne L. Newell-Stamper, Kevin Hunt, Sarah Lehman, Molly Madden, Stephen Schlachter, Ben Robertson, Ashleigh Van Deusen, Hector M. Rodriguez, Carlos Vera, Yu Su, Dennis R. Claflin, Susan V. Brooks, Peter Nghiem, Alexis Rutledge, Twlya I. Juehne, Jinsheng Yu, Elisabeth R. Barton, Yangyi E. Luo, Andreas Patsalos, Laszlo Nagy, H. Lee Sweeney, Leslie A. Leinwand, Kevin Koch
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 10 (2023)
Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by absence of the protein dystrophin, which acts as a structural link between the basal lamina and contractile machinery to stabilize muscle membranes in response to mechanical stres
Externí odkaz:
https://doaj.org/article/e747694ac75a437988e03985ae826a25
Evaluation of the DBA/2J mouse as a potential background strain for genetic models of cardiomyopathy
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 1, Iss , Pp 100012- (2022)
The potential use of the D2.mdx mouse (the mdx mutation on the DBA/2J genetic background) as a preclinical model of the cardiac aspects of Duchenne muscular dystrophy (DMD) has been criticized based on speculation that the DBA/2J genetic background d
Externí odkaz:
https://doaj.org/article/d5874e8fce8a4c6b95171c1ed9ba578d
Publikováno v:
European Journal of Translational Myology (2022)
In the autumn of 2021, the 2022 Padua Days of Muscle and Mobility Medicine (PDM3) was planned to be held from March 30 to April 2, 2022. Despite the fact that Coronavirus COVID-19 outbreak continued to impose restrictions all over the world, the prog
Externí odkaz:
https://doaj.org/article/d0cb61ae54f941a7bbeae3954b98310e
Publikováno v:
eLife, Vol 10 (2021)
The molecular motor myosin undergoes a series of major structural transitions during its force-producing motor cycle. The underlying mechanism and its coupling to ATP hydrolysis and actin binding are only partially understood, mostly due to sparse st
Externí odkaz:
https://doaj.org/article/7a02ba89d5714ea9b1e6fe77d851f4db
Autor:
David W Hammers, Cora C Hart, Michael K Matheny, Ernest G Heimsath, Young il Lee, John A Hammer III, Richard E Cheney, H Lee Sweeney
Publikováno v:
eLife, Vol 10 (2021)
Skeletal muscle fibers are multinucleated cellular giants formed by the fusion of mononuclear myoblasts. Several molecules involved in myoblast fusion have been discovered, and finger-like projections coincident with myoblast fusion have also been im
Externí odkaz:
https://doaj.org/article/d55126ce59ca4aeab1c75999d010f99e