Zobrazeno 1 - 10
of 130
pro vyhledávání: '"H Lassen"'
Autor:
Nechama Wieder, Elston N. D’Souza, Alexandra C. Martin-Geary, Frederik H. Lassen, Jonathan Talbot-Martin, Maria Fernandes, Sonia P. Chothani, Owen J. L. Rackham, Sebastian Schafer, Julie L. Aspden, Daniel G. MacArthur, Robert W. Davies, Nicola Whiffin
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Untranslated regions (UTRs) are important mediators of post-transcriptional regulation. The length of UTRs and the composition of regulatory elements within them are known to vary substantially across genes, but little is known ab
Externí odkaz:
https://doaj.org/article/419dbeb079c94514871454c4158e40f1
Autor:
Qiuyu Martin Zhu, Yu-Han H. Hsu, Frederik H. Lassen, Bryan T. MacDonald, Stephanie Stead, Edyta Malolepsza, April Kim, Taibo Li, Taiji Mizoguchi, Monica Schenone, Gaelen Guzman, Benjamin Tanenbaum, Nadine Fornelos, Steven A. Carr, Rajat M. Gupta, Patrick T. Ellinor, Kasper Lage
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Population-based association studies have identified many genetic risk loci for coronary artery disease (CAD), but it is often unclear how genes within these loci are linked to CAD. Here, we perform interaction proteomics for 11 CAD-risk gen
Externí odkaz:
https://doaj.org/article/33f24fe85b5e427da89e1cdd0af7dd9f
Autor:
Zhu Liang, Andreas Damianou, Iolanda Vendrell, Edward Jenkins, Frederik H. Lassen, Sam J. Washer, Athina Grigoriou, Guihai Liu, Gangshun Yi, Hantao Lou, Fangyuan Cao, Xiaonan Zheng, Ricardo A. Fernandes, Tao Dong, Edward W. Tate, Elena Di Daniel, Benedikt M. Kessler
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114152- (2024)
Summary: Activation of the NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome complex is an essential innate immune signaling mechanism. To reveal how human NLRP3 inflammasome assembly and activation are controlled, in particular b
Externí odkaz:
https://doaj.org/article/a5167cfa972c4f8d8edd1f27601d7520
Autor:
Greta Pintacuda, Frederik H. Lassen, Yu-Han H. Hsu, April Kim, Jacqueline M. Martín, Edyta Malolepsza, Justin K. Lim, Nadine Fornelos, Kevin C. Eggan, Kasper Lage
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Genetic variation can impact protein complexes and interaction networks, but reconciling genetic and proteomic information remains challenging. To address this need, the authors develop Genoppi —a computational tool for integrating genetics and cel
Externí odkaz:
https://doaj.org/article/6220d61e41354d62afdc46a4aa7d453e
Autor:
Mats C. H. Lassen, Atif N. Qasim, Tor Biering-Sørensen, Jacob L. T. Reeh, Terry Watnick, Stephen L. Seliger, Huanwen Chen, Mariem A. Sawan, Daniel Nguyen, Yongfang Li, Susie N. Hong, Meyeon Park
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background Patients with autosomal dominant polycystic kidney disease (ADPKD) have an increased risk of cardiovascular morbidity and mortality. Impaired left ventricular (LV) global longitudinal strain (GLS) can be a sign of subclinical card
Externí odkaz:
https://doaj.org/article/2ba5499ccd0c43baa351d8835f7d4633
Autor:
Kieran L, Quinn, Husam, Abdel-Qadir, Kali, Barrett, Emily, Bartsch, Andrea, Beaman, Tor, Biering-Sørensen, Michael, Colacci, Alex, Cressman, Allan, Detsky, Alexi, Gosset, Mats H, Lassen, Chris, Kandel, Yaariv, Khaykin, Lauren, Lapointe-Shaw, Erik, Lovblom, Derek R, MacFadden, Bruce, Perkins, Kenneth J, Rothman, Kristoffer G, Skaarup, Nathan, Stall, Terence, Tang, Chris, Yarnell, Jonathan, Zipursky, Matthew T, Warkentin, Mike, Fralick, Rachael, Weagle
Publikováno v:
Journal of Hospital Medicine. 17:793-802
There is wide variation in mortality among patients hospitalized with COVID-19. Whether this is related to patient or hospital factors is unknown.To compare the risk of mortality for patients hospitalized with COVID-19 and to determine whether the ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975094e343c1e63ffd27428118ddb376
https://doi.org/10.1002/jhm.12946
https://doi.org/10.1002/jhm.12946
Autor:
Nechama Wieder, Elston N. D’Souza, Alexandra C. Martin-Geary, Frederik H. Lassen, Jonathan Talbot-Martin, Maria Fernandes, Sonia P. Chothani, Owen J.L. Rackham, Sebastian Schafer, Julie L. Aspden, Daniel G. MacArthur, Robert W. Davies, Nicola Whiffin
BackgroundUntranslated regions (UTRs) are important mediators of post-transcriptional regulation. The length of UTRs and the composition of regulatory elements within them are known to vary substantially across genes, but little is known about the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fd08583ee4317e803c8a2491067c221
https://doi.org/10.1101/2023.05.15.540809
https://doi.org/10.1101/2023.05.15.540809
Autor:
Tor Biering-Sørensen, Maja Cikes, Mats C H Lassen, Brian Claggett, Masatoshi Minamisawa, Angela B S Santos, Elisabeth Pieske-Kraigher, Amil M Shah, Michael R Zile, John J V McMurray, Scott D Solomon, Susan Cheng
Publikováno v:
European Heart Journal - Cardiovascular Imaging.
Aims Hypertensive heart disease (HHD) is recognized as a key clinical precursor to heart failure with preserved ejection fraction (HFPEF). However, pathophysiological transition from HHD to HFPEF is not well understood. We sought determine whether re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::243499021c939d1069a8f9cf26f9861c
https://doi.org/10.1093/ehjci/jead062
https://doi.org/10.1093/ehjci/jead062
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.