ABSTRACTS FOR ORAL PRESENTATION, SESSION 3, HRC 2013

Autor: G. Lee, R. Hunter, M. Lovell, M. Finlay, V. Sawhney, W. Ullah, I. Diab, M. Dhinoja, M. Earley, S. Sporton, R. J. Schilling, S. E. Williams, N. W. F. Linton, J. Harrison, M. Wright, M. O'Neill, S. Jamil-Copley, N. Linton, M. Koa-Wing, P. B. Lim, S. Hayat, N. Qureshi, Z. Whinnett, W. Davies, N. Peters, D. Francis, P. Kanagaratnam, B. Ryan, P. Kojodjojo, A. Kyriacou, B. Sandler, A. Sohaib, I. Wright, N. A. Qureshi, W. Bai, B. Ariff, A. Williams, C. Monro, S. Kim, M. Kao-Wing, N. S. Fu, D. W. Davies, D. Lefroy, N. S. Peters, M. J. Ryan, V. A. Ezzat, J. O'Leary, C. Bull, A. Chow, P. Lambiase, M. D. Lowe, A. S. Anwar, S. Collitt, P. Iddon, N. Rice, M. Dodd, A. Dunsdale, S. Petkar, J. Mudd, N. Linker, A. P. Fitzpatrick, S. Fraser, W. K. Choo, G. Padfield, G. Rushworth, C. Bloe, P. Forsyth, S. J. Cross, S. J. Leslie, T. T. Phan, M. Dewhurst, D. Lee, D. Williams, S. James, A. Thornley, M. de Belder, A. Turley, N. G. Campbell, E. Cantor, E. R. Duncan, C. Demartini, V. Baker, I. G. Diab, M. J. Earley, L. C. Davies, S. J. Pettit, D. A. Randles, M. Shaw, N. M. Hawkins, D. J. Wright, P. D. Lambiase, C. Barr, R. Knops, P. Neuzil, D. Theuns, J. B. Johansen, M. Hood, S. Pederson, H. L. Reeve, L. Boersma

Publikováno v: Europace. 15:iv14-iv18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca2b1f9cdda13eda97601c05396fc6d9
https://doi.org/10.1093/europace/eut316

Molecular Identification of O2 Sensors and O2-Sensitive Potassium Channels in the Pulmonary Circulation

Autor: Evangelos D. Michelakis, H. L. Reeve, Stephen L. Archer, Edward K Weir

Publikováno v: Oxygen Sensing ISBN: 9780306463679

Small, muscular pulmonary arteries (PAs) constrict within seconds of the onset of alveolar hypoxia, diverting blood flow to better-ventilated lobes, thereby matching ventilation to perfusion and optimizing systemic PO2. This hypoxic pulmonary vasocon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7f3e94ace0189c58912ac84cdd817a0
https://doi.org/10.1007/0-306-46825-5_21

Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells

Autor: E D, Michelakis, E K, Weir, D P, Nelson, H L, Reeve, S, Tolarova, S L, Archer

Publikováno v: The Journal of pharmacology and experimental therapeutics. 291(3)

Appetite suppressants, such as dexfenfluramine (dex), are associated with primary pulmonary hypertension, valvular heart disease, and systemic vascular complications, such as coronary, cerebral, or mesenteric ischemia. These drugs suppress appetite b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eb86ccf06f280fc3aa79e6300e896189
https://pubmed.ncbi.nlm.nih.gov/10565835

Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture

Autor: E K, Weir, H L, Reeve, D A, Peterson, E D, Michelakis, D P, Nelson, S L, Archer

Publikováno v: Chest. 114

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0322cf8393e06cc7e9da4d6cbc5cbbe9
https://pubmed.ncbi.nlm.nih.gov/9676606

Potassium channel diversity in vascular smooth muscle cells

Autor: E D, Michelakis, H L, Reeve, J M, Huang, S, Tolarova, D P, Nelson, E K, Weir, S L, Archer

Publikováno v: Canadian journal of physiology and pharmacology. 75(7)

Several recent observations suggest that the vascular medium is a mosaic of functionally and morphologically unique cell types. This diversity includes differences in cell phenotype and expression of cytoskeletal and contractile proteins as well as h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9905b58e5fa2d9e2dd20bd22ee8ffe8c
https://pubmed.ncbi.nlm.nih.gov/9315358