Výsledky vyhledávání - "H L, Bonkovsky"

Association of filamin A and vimentin with hepatitis C virus proteins in infected human hepatocytes

Autor: S, Ghosh, W A, Ahrens, S U, Phatak, S, Hwang, L W, Schrum, H L, Bonkovsky

Publikováno v: Journal of viral hepatitis. 18(10)

Chronic hepatitis C (CHC) infection caused by hepatitis C virus (HCV) is a major cause of liver disease and remains a major therapeutic challenge. A variety of host proteins interact with HCV proteins. The definitive role of cytoskeletal (CS) protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf99988280734ddb6d90c4c676f60d5f
https://pubmed.ncbi.nlm.nih.gov/21914078

Zobrazit plný text záznamu

Changes in quality of life and sexual health are associated with low-dose peginterferon therapy and disease progression in patients with chronic hepatitis C

Autor: K K, Snow, H L, Bonkovsky, R J, Fontana, H-Y, Kim, R K, Sterling, A M, Di Bisceglie, T R, Morgan, J L, Dienstag, M G, Ghany

Publikováno v: Alimentary pharmacologytherapeutics. 31(7)

Primary analysis of the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis (HALT-C) Trial showed long-term peginterferon therapy did not reduce complications in patients with chronic hepatitis C and advanced fibrosis or cirrhosis.To assess t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2d61960371caa3ad11d95721a5f65820
https://pubmed.ncbi.nlm.nih.gov/20070284

Zobrazit plný text záznamu

Plný text ve formátu HTML

Induction of heme oxygenase-1 by phenylarsine oxide. Studies in cultured primary liver cells

Autor: O S, Gildemeister, J A, Pepe, R W, Lambrecht, H L, Bonkovsky

Publikováno v: Molecular and cellular biochemistry. 226(1-2)

Heme oxygenase-1, the major inducible isoform of heme oxygenase (HO), can be induced by heme and numerous other physical and chemical factors, many of which cause cellular 'stress'. This has led to the realization that HO-1 is a major highly conserve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a4970d485293fe378fa01be2ae0e3a4
https://pubmed.ncbi.nlm.nih.gov/11768235

Zobrazit plný text záznamu

Comparative effects of different doses of ribavirin plus interferon-alpha2b for therapy of chronic hepatitis C: results of a controlled, randomized trial

Autor: H L, Bonkovsky, D, Stefancyk, K, McNeal, B F, Banner, Q, Liu, G M, Zucker, J, Israel, J, Stagias, J, Colker

Publikováno v: Digestive diseases and sciences. 46(10)

Compared to either drug alone, therapy with the combination of ribavirin and interferon-alpha leads to improved rates of response in patients with chronic hepatitis C. Side effects often mandate downward dose adjustment or cessation of therapy, and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0cdcd31972b21f22615ecfdb98295d58
https://pubmed.ncbi.nlm.nih.gov/11680575

Zobrazit plný text záznamu

Upstream regulatory elements in chick heme oxygenase-1 promoter: a study in primary cultures of chick embryo liver cells

Autor: T H, Lu, Y, Shan, J, Pepe, R W, Lambrecht, H L, Bonkovsky

Publikováno v: Molecular and cellular biochemistry. 209(1-2)

Previously, chick heme oxygenase-1 (cHO-1) gene was cloned by us and two regions important for induction by sodium arsenite were identified. These two regions were found to contain consensus sequences of an AP-1 (-1580 to -1573) and a MRE/cMyc comple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::800d85f07575046852c8c5462a4af55b
https://pubmed.ncbi.nlm.nih.gov/10942197

Zobrazit plný text záznamu

Iron reduction before and during interferon therapy of chronic hepatitis C: results of a multicenter, randomized, controlled trial

Autor: R J, Fontana, J, Israel, P, LeClair, B F, Banner, K, Tortorelli, N, Grace, R A, Levine, G, Fiarman, M, Thiim, A S, Tavill, H L, Bonkovsky

Publikováno v: Hepatology (Baltimore, Md.). 31(3)

Patients with chronic hepatitis C and low serum and hepatic iron stores may have an improved response to interferon (IFN). We tested whether iron reduction before and during IFN therapy would lead to an improved sustained biochemical and virological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc88622857dca779550ebcb32cd18926
https://pubmed.ncbi.nlm.nih.gov/10706565

Zobrazit plný text záznamu

Effects of antidepressants and benzodiazepine-type anxiolytic agents on hepatic porphyrin accumulation in primary cultures of chick embryo liver cells

Autor: R W, Lambrecht, O S, Gildemeister, J A, Pepe, K D, Tortorelli, A, Williams, H L, Bonkovsky

Publikováno v: The Journal of pharmacology and experimental therapeutics. 291(3)

Patients with any of the acute porphyrias may suffer from acute attacks. If these patients are treated with certain drugs, such as barbiturates, the likelihood of developing an attack is increased. Patients treated with antidepressants or benzodiazep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f665b858eef9233178279029ead400dc
https://pubmed.ncbi.nlm.nih.gov/10565836

Zobrazit plný text záznamu

Heme oxygenase: recent advances in understanding its regulation and role

Autor: K K, Elbirt, H L, Bonkovsky

Publikováno v: Proceedings of the Association of American Physicians. 111(5)

Heme oxygenase (HO) is responsible for the physiological breakdown of heme into equimolar amounts of biliverdin, carbon monoxide, and iron. Three isoforms (HO-1, HO-2, and HO-3) have been identified. HO-1 is ubiquitous and its mRNA and activity can b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7d3f0347db566f2266b3d6409e293992
https://pubmed.ncbi.nlm.nih.gov/10519165

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání